This is a Validated Antibody Database (VAD) review about human MKRN1, based on 4 published articles (read how Labome selects the articles), using MKRN1 antibody in all methods. It is aimed to help Labome visitors find the most suited MKRN1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MKRN1 synonym: RNF61; E3 ubiquitin-protein ligase makorin-1; RING finger protein 61; RING-type E3 ubiquitin transferase makorin-1

Knockout validation
Bethyl
rabbit polyclonal
  • immunoprecipitation; human; 1:1000; fig s5,s9
  • immunohistochemistry; human; 1:2000; fig 2a
  • western blot; human; 1:1000; fig 1c
  • western blot knockout validation; mouse; 1:1000; fig 1b
Bethyl MKRN1 antibody (Bethyl Laboratories, A300-990A) was used in immunoprecipitation on human samples at 1:1000 (fig s5,s9), in immunohistochemistry on human samples at 1:2000 (fig 2a), in western blot on human samples at 1:1000 (fig 1c) and in western blot knockout validation on mouse samples at 1:1000 (fig 1b). Nat Commun (2015) ncbi
Bethyl
rabbit polyclonal
  • RNA immunoprecipitation; human
In order to develop reagents to study RNA binding proteins, Bethyl MKRN1 antibody (Bethyl, A300-990A) was used in RNA immunoprecipitation on human samples . Mol Cell (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:1000; fig 2a,s1
Bethyl MKRN1 antibody (Bethyl Laboratories, A300-990A) was used in immunohistochemistry on human samples at 1:1000 (fig 2a,s1). Neurochem Int (2015) ncbi
rabbit polyclonal
  • immunoprecipitation; human; 1:1000; fig s5,s9
  • immunohistochemistry; human; 1:2000; fig 2a
  • western blot; human; 1:1000; fig 1c
  • western blot knockout validation; mouse; 1:1000; fig 1b
Bethyl MKRN1 antibody (Bethyl Laboratories, A300-990A) was used in immunoprecipitation on human samples at 1:1000 (fig s5,s9), in immunohistochemistry on human samples at 1:2000 (fig 2a), in western blot on human samples at 1:1000 (fig 1c) and in western blot knockout validation on mouse samples at 1:1000 (fig 1b). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig s1
Bethyl MKRN1 antibody (Bethyl Laboratories, A300-990A) was used in western blot on mouse samples (fig s1). Biochem Biophys Res Commun (2015) ncbi
Articles Reviewed
  1. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  2. Baburina Y, Azarashvili T, Grachev D, Krestinina O, Galvita A, Stricker R, et al. Mitochondrial 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) interacts with mPTP modulators and functional complexes (I-V) coupled with release of apoptotic factors. Neurochem Int. 2015;90:46-55 pubmed publisher
  3. Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed publisher
  4. Kim J, Jeong M, Lee S, Song J. Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ. Biochem Biophys Res Commun. 2015;463:1122-8 pubmed publisher