This is a Validated Antibody Database (VAD) review about human MIOS, based on 5 published articles (read how Labome selects the articles), using MIOS antibody in all methods. It is aimed to help Labome visitors find the most suited MIOS antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MIOS synonym: MIO; Sea4; Yulink; GATOR complex protein MIOS; H_DJ1159O04.1; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1; missing oocyte, meiosis regulator, homolog

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D12C6)
  • western blot knockout validation; human; loading ...; fig 2f
Cell Signaling Technology MIOS antibody (Cell Signaling, 13557) was used in western blot knockout validation on human samples (fig 2f). Nature (2017) ncbi
R&D Systems
mouse monoclonal (955413)
  • immunocytochemistry; human; 1:250; loading ...; fig s7a
  • western blot; human; 1:250; loading ...; fig s3f
R&D Systems MIOS antibody (R&D Systems, MAB9289-100) was used in immunocytochemistry on human samples at 1:250 (fig s7a) and in western blot on human samples at 1:250 (fig s3f). J Cell Sci (2018) ncbi
Cell Signaling Technology
rabbit monoclonal (D12C6)
  • western blot knockout validation; human; loading ...; fig 2f
Cell Signaling Technology MIOS antibody (Cell Signaling, 13557) was used in western blot knockout validation on human samples (fig 2f). Nature (2017) ncbi
rabbit monoclonal (D12C6)
  • western blot; human; fig 1c
Cell Signaling Technology MIOS antibody (Cell Signaling Technology, 13557) was used in western blot on human samples (fig 1c). Nature (2017) ncbi
rabbit monoclonal (D12C6)
  • western blot; human; fig 6
Cell Signaling Technology MIOS antibody (Cell Signaling Technology, D12C6) was used in western blot on human samples (fig 6). Cell Signal (2016) ncbi
rabbit monoclonal (D12C6)
  • western blot; mouse; fig 1
  • western blot; human; fig s1
Cell Signaling Technology MIOS antibody (Cell Signaling, 13557) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig s1). Sci Rep (2015) ncbi
Articles Reviewed
  1. Platani M, Samejima I, Samejima K, Kanemaki M, Earnshaw W. Seh1 targets GATOR2 and Nup153 to mitotic chromosomes. J Cell Sci. 2018;131: pubmed publisher
  2. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  3. Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
  4. Kimball S, Gordon B, Moyer J, Dennis M, Jefferson L. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Cell Signal. 2016;28:896-906 pubmed publisher
  5. Kim J, Ro S, Kim M, Park H, Semple I, Park H, et al. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Sci Rep. 2015;5:9502 pubmed publisher