This is a Validated Antibody Database (VAD) review about human MICU2, based on 3 published articles (read how Labome selects the articles), using MICU2 antibody in all methods. It is aimed to help Labome visitors find the most suited MICU2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MICU2 synonym: 1110008L20Rik; EFHA1; calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EF-hand domain-containing family member A1; Smhs2 homolog

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; human; 1:500; fig s2
In order to elucidate the role of EMRE as a matrix Ca(2+) sensor that controls gatekeeping of the mitochondrial Ca(2+) uniporter, Abcam MICU2 antibody (abcam, ab101465) was used in western blot knockout validation on human samples at 1:500 (fig s2). Cell Rep (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; 1:500; fig 1
In order to characterize how mitochondrial Ca(21) uptake through MICU1 regulation dictates tissue regeneration and survival, Abcam MICU2 antibody (Abcam, ab101465) was used in western blot on mouse samples at 1:500 (fig 1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; human; 1:500; fig s2
In order to elucidate the role of EMRE as a matrix Ca(2+) sensor that controls gatekeeping of the mitochondrial Ca(2+) uniporter, Abcam MICU2 antibody (abcam, ab101465) was used in western blot knockout validation on human samples at 1:500 (fig s2). Cell Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4a
In order to report the crystal structure of the mitochondrial calcium uniporter N-terminal domain and assess its function, Abcam MICU2 antibody (Abcam, ab101465) was used in western blot on human samples (fig 4a). EMBO Rep (2015) ncbi
Articles Reviewed
  1. Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher
  2. Vais H, Mallilankaraman K, Mak D, Hoff H, Payne R, Tanis J, et al. EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter. Cell Rep. 2016;14:403-410 pubmed publisher
  3. Lee Y, Min C, Kim T, Song H, Lim Y, Kim D, et al. Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. EMBO Rep. 2015;16:1318-33 pubmed publisher