This is a Validated Antibody Database (VAD) review about human MICB, based on 16 published articles (read how Labome selects the articles), using MICB antibody in all methods. It is aimed to help Labome visitors find the most suited MICB antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MICB synonym: PERB11.2

BioLegend
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig 1a
BioLegend MICB antibody (BioLegend, 320906) was used in flow cytometry on human samples (fig 1a). J Exp Clin Cancer Res (2021) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig 3
BioLegend MICB antibody (BioLegend, 320906) was used in flow cytometry on human samples (fig 3). Stem Cell Reports (2020) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig 2b
BioLegend MICB antibody (Biolegend, 320906) was used in flow cytometry on human samples (fig 2b). Biosci Rep (2019) ncbi
mouse monoclonal (6D4)
  • immunocytochemistry; human; loading ...; fig 1b
  • immunohistochemistry; human; loading ...; fig 2a
In order to study the expression of MHC class I chain-related protein A and B in tumour and normal tissue, BioLegend MICB antibody (BioLegend, 6D4) was used in immunocytochemistry on human samples (fig 1b) and in immunohistochemistry on human samples (fig 2a). Br J Cancer (2017) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig s3g
BioLegend MICB antibody (BioLegend, 6D4) was used in flow cytometry on human samples (fig s3g). Oncogene (2017) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; fig 4
BioLegend MICB antibody (Biolegend, 6D4) was used in flow cytometry on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; fig 7
In order to investigate the dynamics and characteristics of natural killer cell types in the human ocular mucosal surface in situ during infection with group D human adenoviruses, BioLegend MICB antibody (Biolegend, 6D4) was used in flow cytometry on human samples (fig 7). Mucosal Immunol (2016) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human
BioLegend MICB antibody (Biolegend, 6D4) was used in flow cytometry on human samples . Immunology (2014) ncbi
mouse monoclonal (6D4)
BioLegend MICB antibody (Biolegend, 6D4) was used . Int Immunol (2014) ncbi
R&D Systems
mouse monoclonal (236511)
  • flow cytometry; human; loading ...; fig 2b
R&D Systems MICB antibody (R&D Systems, 236511) was used in flow cytometry on human samples (fig 2b). BMC Biol (2021) ncbi
Invitrogen
mouse monoclonal (6D4)
  • immunocytochemistry; human
  • immunohistochemistry; human
Invitrogen MICB antibody (eBioscience, 6D4) was used in immunocytochemistry on human samples and in immunohistochemistry on human samples . Exp Mol Pathol (2014) ncbi
Miltenyi Biotec
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig s1d
Miltenyi Biotec MICB antibody (Miltenyi Biotec, 6D4) was used in flow cytometry on human samples (fig s1d). J Immunol (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-6)
  • immunohistochemistry - paraffin section; human; 1:800; fig 1
Santa Cruz Biotechnology MICB antibody (Santa Cruz Biotechnology, sc-137242) was used in immunohistochemistry - paraffin section on human samples at 1:800 (fig 1). Cancer Sci (2016) ncbi
BD Biosciences
mouse monoclonal (6D4)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences MICB antibody (BD, 558352) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; loading ...; fig 1a
BD Biosciences MICB antibody (BD Biosciences, 558352) was used in flow cytometry on human samples (fig 1a). J Immunol (2014) ncbi
mouse monoclonal (6D4)
  • flow cytometry; human; tbl 1
BD Biosciences MICB antibody (BD Pharmingen, 558352) was used in flow cytometry on human samples (tbl 1). Cell Transplant (2014) ncbi
Articles Reviewed
  1. Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed publisher
  2. Hirano M, Imai Y, Kaito Y, Murayama T, Sato K, Ishida T, et al. Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myeloma. J Exp Clin Cancer Res. 2021;40:110 pubmed publisher
  3. Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, et al. iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity. Stem Cell Reports. 2020;14:49-59 pubmed publisher
  4. Tang S, Fu H, Xu Q, Zhou Y. miR-20a regulates sensitivity of colorectal cancer cells to NK cells by targeting MICA. Biosci Rep. 2019;: pubmed publisher
  5. Walwyn Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald A, et al. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1. J Immunol. 2018;201:2028-2041 pubmed publisher
  6. Ghadially H, Brown L, Lloyd C, Lewis L, LEWIS A, Dillon J, et al. MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue. Br J Cancer. 2017;116:1208-1217 pubmed publisher
  7. Sauer M, Schuldner M, Hoffmann N, Cetintas A, Reiners K, Shatnyeva O, et al. CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells. Oncogene. 2017;36:933-941 pubmed publisher
  8. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  9. Ritter C, Fan K, Paulson K, Nghiem P, Schrama D, Becker J. Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma. Sci Rep. 2016;6:21678 pubmed publisher
  10. Tsukagoshi M, Wada S, Yokobori T, Altan B, Ishii N, Watanabe A, et al. Overexpression of natural killer group 2 member D ligands predicts favorable prognosis in cholangiocarcinoma. Cancer Sci. 2016;107:116-22 pubmed publisher
  11. Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
  12. Uhlenbrock F, Hagemann Jensen M, Kehlet S, Andresen L, Pastorekova S, Skov S. The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway. J Immunol. 2014;193:1654-65 pubmed publisher
  13. Ikeshita S, Miyatake Y, Otsuka N, Kasahara M. MICA/B expression in macrophage foam cells infiltrating atherosclerotic plaques. Exp Mol Pathol. 2014;97:171-5 pubmed publisher
  14. Vogel K, Thomann S, Vogel B, Schuster P, Schmidt B. Both plasmacytoid dendritic cells and monocytes stimulate natural killer cells early during human herpes simplex virus type 1 infections. Immunology. 2014;143:588-600 pubmed publisher
  15. Watanabe M, Kudo Y, Kawano M, Nakayama M, Nakamura K, Kameda M, et al. NKG2D functions as an activating receptor on natural killer cells in the common marmoset (Callithrix jacchus). Int Immunol. 2014;26:597-606 pubmed publisher
  16. Jacobs S, Plessers J, Pinxteren J, Roobrouck V, Verfaillie C, Van Gool S. Mutual interaction between human multipotent adult progenitor cells and NK cells. Cell Transplant. 2014;23:1099-110 pubmed publisher