This is a Validated Antibody Database (VAD) review about human METTL14, based on 10 published articles (read how Labome selects the articles), using METTL14 antibody in all methods. It is aimed to help Labome visitors find the most suited METTL14 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
METTL14 synonym: hMETTL14

Knockout validation
MilliporeSigma
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 3c
MilliporeSigma METTL14 antibody (Sigma-Aldrich, HPA038002) was used in western blot knockout validation on mouse samples (fig 3c). Cell Mol Gastroenterol Hepatol (2021) ncbi
Abcam
mouse monoclonal (CL4252)
  • western blot; human; loading ...; fig s4g
Abcam METTL14 antibody (Abcam, ab220030) was used in western blot on human samples (fig s4g). Mol Cancer (2021) ncbi
mouse monoclonal (CL4252)
  • western blot; human; fig s3f
Abcam METTL14 antibody (Abcam, Ab220030) was used in western blot on human samples (fig s3f). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (CL4252)
  • western blot; human; loading ...; fig s5i
Abcam METTL14 antibody (Abcam, ab220030) was used in western blot on human samples (fig s5i). Redox Biol (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1g
  • immunocytochemistry; human; loading ...; fig 7e
  • western blot; human; loading ...; fig 5a
MilliporeSigma METTL14 antibody (Sigma, HPA038002) was used in western blot on mouse samples (fig 1g), in immunocytochemistry on human samples (fig 7e) and in western blot on human samples (fig 5a). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 2d
  • western blot; mouse; loading ...; fig 2b
MilliporeSigma METTL14 antibody (Sigma-Aldrich, HPA038002) was used in immunohistochemistry on mouse samples (fig 2d) and in western blot on mouse samples (fig 2b). J Cell Mol Med (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 3c
MilliporeSigma METTL14 antibody (Sigma-Aldrich, HPA038002) was used in western blot knockout validation on mouse samples (fig 3c). Cell Mol Gastroenterol Hepatol (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s2d
MilliporeSigma METTL14 antibody (Sigma, HPA038002) was used in immunocytochemistry on mouse samples at 1:1000 (fig s2d). Nucleic Acids Res (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
MilliporeSigma METTL14 antibody (Sigma, HPA038002) was used in western blot on human samples (fig 2c). Mol Cell (2016) ncbi
domestic rabbit polyclonal
MilliporeSigma METTL14 antibody (Sigma, HPA038002) was used . Nature (2015) ncbi
domestic rabbit polyclonal
MilliporeSigma METTL14 antibody (Sigma, HPA038002) was used . Nature (2015) ncbi
Articles Reviewed
  1. Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed publisher
  2. Liu Z, Wang T, She Y, Wu K, Gu S, Li L, et al. N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer. Mol Cancer. 2021;20:105 pubmed publisher
  3. Teng Y, Liu Z, Chen X, Liu Y, Geng F, Le W, et al. Conditional deficiency of m6A methyltransferase Mettl14 in substantia nigra alters dopaminergic neuron function. J Cell Mol Med. 2021;25:8567-8572 pubmed publisher
  4. Hua Y, Zhang K, Sheng J, Ning Z, Li Y, Shi W, et al. NUCB1 Suppresses Growth and Shows Additive Effects With Gemcitabine in Pancreatic Ductal Adenocarcinoma via the Unfolded Protein Response. Front Cell Dev Biol. 2021;9:641836 pubmed publisher
  5. Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, et al. Mettl14-Mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12:633-651 pubmed publisher
  6. Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, et al. The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function. Redox Biol. 2021;38:101801 pubmed publisher
  7. Yu J, Chen M, Huang H, Zhu J, Song H, Zhu J, et al. Dynamic m6A modification regulates local translation of mRNA in axons. Nucleic Acids Res. 2018;46:1412-1423 pubmed publisher
  8. Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
  9. Zhou J, Wan J, Gao X, Zhang X, Jaffrey S, Qian S. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. 2015;526:591-4 pubmed publisher
  10. Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015;518:560-4 pubmed publisher