This is a Validated Antibody Database (VAD) review about human ME3, based on 3 published articles (read how Labome selects the articles), using ME3 antibody in all methods. It is aimed to help Labome visitors find the most suited ME3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ME3 synonym: NADP-ME; NADP-dependent malic enzyme, mitochondrial; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malic enzyme 3, NADP(+)-dependent, mitochondrial; malic enzyme, NADP+-dependent, mitochondrial; mitochondrial NADP(+)-dependent malic enzyme 3; pyruvic-malic carboxylase

Abcam
rabbit monoclonal (EPR10378)
  • western blot; human; loading ...; fig 2b
Abcam ME3 antibody (Abcam, ab172972) was used in western blot on human samples (fig 2b). Nature (2017) ncbi
rabbit monoclonal (EPR10378)
  • western blot; mouse; 1:2000; loading ...; fig s9a
Abcam ME3 antibody (Abcam, ab172972) was used in western blot on mouse samples at 1:2000 (fig s9a). Nat Chem Biol (2016) ncbi
rabbit monoclonal (EPR10378)
  • western blot; rabbit; fig 1.2.7
Abcam ME3 antibody (Abcam, ab172972) was used in western blot on rabbit samples (fig 1.2.7). Mol Endocrinol (2015) ncbi
Articles Reviewed
  1. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  2. Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12:345-52 pubmed publisher
  3. Hasan N, Longacre M, Stoker S, Kendrick M, MacDonald M. Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells. Mol Endocrinol. 2015;29:396-410 pubmed publisher