This is a Validated Antibody Database (VAD) review about human ME1, based on 8 published articles (read how Labome selects the articles), using ME1 antibody in all methods. It is aimed to help Labome visitors find the most suited ME1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ME1 synonym: HUMNDME; MES; NADP-dependent malic enzyme; Malic enzyme, cytoplasmic; NADP-ME; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; pyruvic-malic carboxylase

Santa Cruz Biotechnology
mouse monoclonal (99.1)
  • western blot; mouse; 1:2000; loading ...; fig 5b
Santa Cruz Biotechnology ME1 antibody (Santa Cruz, sc-100569) was used in western blot on mouse samples at 1:2000 (fig 5b). Cancer Res (2017) ncbi
mouse monoclonal (99.1)
  • western blot; human; 1:1000; loading ...; fig 5a
Santa Cruz Biotechnology ME1 antibody (Santa Cruz Biotechnology, sc-100569) was used in western blot on human samples at 1:1000 (fig 5a). Cell Death Differ (2017) ncbi
mouse monoclonal (99.1)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology ME1 antibody (Santa Cruz Biotechnology, sc-100569) was used in western blot on human samples (fig 2b). Nature (2017) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5i
Abcam ME1 antibody (Abcam, ab97445) was used in western blot on mouse samples at 1:1000 (fig 5i). Nat Chem Biol (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig s4
  • western blot; human; 1:1000; fig 7
Abcam ME1 antibody (abcam, ab97445) was used in immunohistochemistry on human samples at 1:100 (fig s4) and in western blot on human samples at 1:1000 (fig 7). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:300; fig s6
Abcam ME1 antibody (Abcam, ab97445) was used in immunohistochemistry on mouse samples at 1:300 (fig s6). J Clin Invest (2015) ncbi
rabbit polyclonal
  • western blot; mouse
In order to study the metabolic responses during chronic pressure overloads in mouse hearts expressing ssTnI, Abcam ME1 antibody (Abcam, ab97445) was used in western blot on mouse samples . Circ Heart Fail (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5, 7
In order to identify the role of intestinal cytosolic malic enzyme 1, Abcam ME1 antibody (Abcam, ab97445) was used in western blot on mouse samples at 1:1000 (fig 5, 7). PLoS ONE (2014) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200
In order to identify the role of intestinal cytosolic malic enzyme 1, Proteintech Group ME1 antibody (Proteintech Group, 16619-1-AP) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Ngo H, Kim D, Cha Y, Na H, Surh Y. Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis. Cancer Res. 2017;77:4797-4808 pubmed publisher
  2. Shen H, Xing C, Cui K, Li Y, Zhang J, Du R, et al. MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1. Cell Death Differ. 2017;24:1253-1262 pubmed publisher
  3. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  4. Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12:345-52 pubmed publisher
  5. Gdynia G, Sauer S, Kopitz J, Fuchs D, Duglova K, Ruppert T, et al. The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun. 2016;7:10764 pubmed publisher
  6. Venkatesh A, Ma S, Le Y, Hall M, Rüegg M, Punzo C. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest. 2015;125:1446-58 pubmed publisher
  7. Carley A, Taglieri D, Bi J, Solaro R, Lewandowski E. Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I. Circ Heart Fail. 2015;8:119-27 pubmed publisher
  8. Al Dwairi A, Brown A, Pabona J, Van T, Hamdan H, Mercado C, et al. Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice. PLoS ONE. 2014;9:e113058 pubmed publisher