This is a Validated Antibody Database (VAD) review about human MDC1, based on 13 published articles (read how Labome selects the articles), using MDC1 antibody in all methods. It is aimed to help Labome visitors find the most suited MDC1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MDC1 synonym: NFBD1

Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1j, 1k
Abcam MDC1 antibody (Abcam, ab11171) was used in western blot on human samples at 1:1000 (fig 1j, 1k). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 4
In order to describe a novel irreversible DNA-damage response in antephase, Abcam MDC1 antibody (Abcam, ab11171) was used in immunocytochemistry on human samples at 1:500 (fig 4). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 4
Abcam MDC1 antibody (Abcam, ab11171) was used in immunocytochemistry on human samples (fig 4) and in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 5
Abcam MDC1 antibody (abcam, ab11169) was used in immunocytochemistry on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 5c
Abcam MDC1 antibody (Abcam, ab11171) was used in immunocytochemistry on human samples (fig 5c). Sci Rep (2016) ncbi
mouse monoclonal (MDC1-50)
  • proximity ligation assay; human; fig 1
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 3
Abcam MDC1 antibody (abcam, ab50003) was used in proximity ligation assay on human samples (fig 1), in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 3). Nucleus (2015) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig s1
In order to study how the Fanconi anemia pathway promotes homologous recombination at stalled replication forks, Abcam MDC1 antibody (Abcam, ab11169) was used in immunocytochemistry on human samples (fig s1). Nucleic Acids Res (2016) ncbi
mouse monoclonal (MDC1-50)
  • immunocytochemistry; human; fig 2a
  • western blot; human; fig 3a
Abcam MDC1 antibody (Abcam, ab50003) was used in immunocytochemistry on human samples (fig 2a) and in western blot on human samples (fig 3a). Genes Dev (2014) ncbi
mouse monoclonal (MDC1-50)
  • western blot; human
Abcam MDC1 antibody (Abcam, ab50003) was used in western blot on human samples . Cell Res (2014) ncbi
Novus Biologicals
domestic rabbit polyclonal (20F430)
  • immunohistochemistry; human; loading ...; fig 1d
Novus Biologicals MDC1 antibody (Novus Biologicals, NB100-397) was used in immunohistochemistry on human samples (fig 1d). Cell Death Differ (2019) ncbi
domestic rabbit polyclonal
Novus Biologicals MDC1 antibody (Novus, NB100-395) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 5
Novus Biologicals MDC1 antibody (Novus Biologicals, NB100-395) was used in immunocytochemistry on human samples (fig 5). Nucleic Acids Res (2016) ncbi
MilliporeSigma
mouse monoclonal (MDC1-50)
  • western blot; human; 1:1000; loading ...; fig 2e
MilliporeSigma MDC1 antibody (Sigma-Aldrich, M2444) was used in western blot on human samples at 1:1000 (fig 2e). Breast Cancer Res (2020) ncbi
Articles Reviewed
  1. Hong H, Jin Z, Qian T, Xu X, Zhu X, Fei Q, et al. Falcarindiol Enhances Cisplatin Chemosensitivity of Hepatocellular Carcinoma via Down-Regulating the STAT3-Modulated PTTG1 Pathway. Front Pharmacol. 2021;12:656697 pubmed publisher
  2. Baker L, Holliday H, Roden D, Krisp C, Wu S, Junankar S, et al. Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. Breast Cancer Res. 2020;22:63 pubmed publisher
  3. Huo D, Chen H, Cheng Y, Song X, Zhang K, Li M, et al. JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity. Cell Death Differ. 2019;: pubmed publisher
  4. Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed publisher
  5. Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed publisher
  6. Zhao M, Song Y, Niu H, Tian Y, Yang X, Xie K, et al. Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy. Oncotarget. 2016;7:8956-67 pubmed publisher
  7. Maculins T, Carter N, Dorval T, Hudson K, Nissink J, Hay R, et al. A Generic Platform for Cellular Screening Against Ubiquitin Ligases. Sci Rep. 2016;6:18940 pubmed publisher
  8. Rassoolzadeh H, Coucoravas C, Farnebo M. The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1. Nucleus. 2015;6:417-24 pubmed publisher
  9. Ge C, Che L, Du C. The UBC Domain Is Required for BRUCE to Promote BRIT1/MCPH1 Function in DSB Signaling and Repair Post Formation of BRUCE-USP8-BRIT1 Complex. PLoS ONE. 2015;10:e0144957 pubmed publisher
  10. Renaud E, Barascu A, Rosselli F. Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res. 2016;44:648-56 pubmed publisher
  11. Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
  12. Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, et al. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev. 2014;28:2726-38 pubmed publisher
  13. Gao M, Wei W, Li M, Wu Y, Ba Z, Jin K, et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res. 2014;24:532-41 pubmed publisher