This is a Validated Antibody Database (VAD) review about human MCT1, based on 19 published articles (read how Labome selects the articles), using MCT1 antibody in all methods. It is aimed to help Labome visitors find the most suited MCT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MCT1 synonym: HHF7; MCT; MCT1; MCT1D

Santa Cruz Biotechnology
mouse monoclonal (H-1)
  • immunohistochemistry; human; 1:100; loading ...; fig 5b
Santa Cruz Biotechnology MCT1 antibody (SantaCruz, sc-365501) was used in immunohistochemistry on human samples at 1:100 (fig 5b). J Clin Med (2022) ncbi
mouse monoclonal (H-1)
  • western blot; human; 1:200; loading ...; fig 1
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, sc-365501) was used in western blot on human samples at 1:200 (fig 1). Pharmaceutics (2021) ncbi
mouse monoclonal (H-1)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4a
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, sc-365501) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 4a). Int J Mol Sci (2020) ncbi
mouse monoclonal (H-1)
  • western blot; human; loading ...; fig 6
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, sc-365501) was used in western blot on human samples (fig 6). Sci Rep (2019) ncbi
mouse monoclonal (H-1)
  • western blot; human; 1:500; loading ...; fig s16b
Santa Cruz Biotechnology MCT1 antibody (Santa, sc-365501) was used in western blot on human samples at 1:500 (fig s16b). Nat Commun (2018) ncbi
mouse monoclonal (H-1)
  • immunocytochemistry; human; 1:15; loading ...; fig 5a
  • western blot; human; 1:25; loading ...; fig 5e
In order to test if long-term exposure to short chain fatty acids affects the transport and metabolism of (poly)phenols by the intestinal epithelium, Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, sc-365501) was used in immunocytochemistry on human samples at 1:15 (fig 5a) and in western blot on human samples at 1:25 (fig 5e). J Nutr Biochem (2017) ncbi
mouse monoclonal (H-1)
  • western blot; human; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, SC-365501) was used in western blot on human samples at 1:1000 (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (H-1)
  • western blot; human; 1:1000; loading ...; fig 2a
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, H-1) was used in western blot on human samples at 1:1000 (fig 2a). Oncotarget (2016) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 2a
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, H-1) was used in western blot on human samples at 1:1000 (fig 2a). Oncotarget (2016) ncbi
mouse monoclonal (H-1)
  • immunocytochemistry; human; 1:50; fig 5
  • western blot; human; 1:25; fig 3
In order to characterize upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4) byan increase in transepithelial transport of ferulic acid by butyric acid, Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, sc-365501) was used in immunocytochemistry on human samples at 1:50 (fig 5) and in western blot on human samples at 1:25 (fig 3). Arch Biochem Biophys (2016) ncbi
mouse monoclonal (H-1)
  • immunocytochemistry; human; 1:200; fig 1
  • immunohistochemistry; human; 1:500; fig 5
  • western blot; human; 1:500; fig 2
Santa Cruz Biotechnology MCT1 antibody (santa Cruz, sc-365501) was used in immunocytochemistry on human samples at 1:200 (fig 1), in immunohistochemistry on human samples at 1:500 (fig 5) and in western blot on human samples at 1:500 (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (H-1)
  • western blot; human
In order to test if FAK is an intrinsic driver that promotes aerobic glycolysis and tumorigenesis, Santa Cruz Biotechnology MCT1 antibody (Santa Cruz Biotechnology, SC-365501) was used in western blot on human samples . Oncogene (2016) ncbi
mouse monoclonal (H-1)
  • flow cytometry; human
  • immunocytochemistry; human; 6.25 ug/ml
  • western blot; human; 1:1000
In order to develop an immunofluorescence method to assess MCT1 and MCT4 in circulating tumor cells and as them as biomarkers of AZD3965 in cancer patients, Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, sc-365501) was used in flow cytometry on human samples , in immunocytochemistry on human samples at 6.25 ug/ml and in western blot on human samples at 1:1000. BMC Cancer (2015) ncbi
mouse monoclonal (H-1)
  • immunohistochemistry; human; 1:500; fig 1
  • western blot; human; 1:500; fig 5
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, sc-365501) was used in immunohistochemistry on human samples at 1:500 (fig 1) and in western blot on human samples at 1:500 (fig 5). J Pathol (2015) ncbi
mouse monoclonal (H-1)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology MCT1 antibody (Santa Cruz, sc-365501) was used in immunocytochemistry on human samples and in western blot on human samples . J Cell Mol Med (2015) ncbi
Invitrogen
mouse monoclonal (P14612)
  • western blot; human; 1:1000; loading ...; fig 10a
  • immunocytochemistry; mouse; 1:500; loading ...; fig 7a
  • western blot; mouse; 1:1000; loading ...; fig 5b
Invitrogen MCT1 antibody (ThermoFisher, MA5-18288) was used in western blot on human samples at 1:1000 (fig 10a), in immunocytochemistry on mouse samples at 1:500 (fig 7a) and in western blot on mouse samples at 1:1000 (fig 5b). Sci Data (2020) ncbi
mouse monoclonal (P14612)
  • western blot; human; 1:1000; loading ...; fig 1a
Invitrogen MCT1 antibody (ThermoFisher Scientific, MA5-18288) was used in western blot on human samples at 1:1000 (fig 1a). Cancer Cell Int (2019) ncbi
Abcam
mouse polyclonal
  • western blot; human; 1:2000; loading ...; fig 4h
Abcam MCT1 antibody (abcam, ab90582) was used in western blot on human samples at 1:2000 (fig 4h). Front Cell Dev Biol (2021) ncbi
mouse polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
Abcam MCT1 antibody (Abcam, ab90582) was used in western blot on mouse samples at 1:1000 (fig 1b). Cell Signal (2018) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; dogs; 1:500; loading ...; fig 1b
In order to characterize autosomal recessive bestrophinopathy mutations, Abcam MCT1 antibody (Abcam, ab85021) was used in immunocytochemistry on dogs samples at 1:500 (fig 1b). Dis Model Mech (2016) ncbi
Articles Reviewed
  1. Malinowski D, Grzeg xf3 x142 kowski P, Piotrowska K, S x142 ojewski M, Dro x17a dzik M. Membrane Transporters and Carriers in Human Seminal Vesicles. J Clin Med. 2022;11: pubmed publisher
  2. Guo Y, Liu B, Liu Y, Sun W, Gao W, Mao S, et al. Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma. Front Cell Dev Biol. 2021;9:690796 pubmed publisher
  3. Tavares Valente D, Sousa B, Schmitt F, Baltazar F, Queir xf3 s O. Disruption of pH Dynamics Suppresses Proliferation and Potentiates Doxorubicin Cytotoxicity in Breast Cancer Cells. Pharmaceutics. 2021;13: pubmed publisher
  4. Lee S, Hadipour Lakmehsari S, Kim D, Di Paola M, Kuzmanov U, Shah S, et al. Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium. Sci Data. 2020;7:425 pubmed publisher
  5. Drozdzik M, Szeląg Pieniek S, Grzegółkowska J, Łapczuk Romańska J, Post M, Domagała P, et al. Monocarboxylate Transporter 1 (MCT1) in Liver Pathology. Int J Mol Sci. 2020;21: pubmed publisher
  6. Hou L, Zhao Y, Song G, Ma Y, Jin X, Jin S, et al. Interfering cellular lactate homeostasis overcomes Taxol resistance of breast cancer cells through the microRNA-124-mediated lactate transporter (MCT1) inhibition. Cancer Cell Int. 2019;19:193 pubmed publisher
  7. Ferreira D, Silva A, Nóbrega F, Martins I, Barbosa Matos C, Granja S, et al. Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display. Sci Rep. 2019;9:3958 pubmed publisher
  8. Persi E, Duran Frigola M, Damaghi M, Roush W, Aloy P, Cleveland J, et al. Systems analysis of intracellular pH vulnerabilities for cancer therapy. Nat Commun. 2018;9:2997 pubmed publisher
  9. Schönrogge M, Kerndl H, Zhang X, Kumstel S, Vollmar B, Zechner D. α-cyano-4-hydroxycinnamate impairs pancreatic cancer cells by stimulating the p38 signaling pathway. Cell Signal. 2018;47:101-108 pubmed publisher
  10. Van Rymenant E, Abranko L, Tumova S, Grootaert C, Van Camp J, Williamson G, et al. Chronic exposure to short-chain fatty acids modulates transport and metabolism of microbiome-derived phenolics in human intestinal cells. J Nutr Biochem. 2017;39:156-168 pubmed publisher
  11. Knudsen E, Balaji U, Freinkman E, McCue P, Witkiewicz A. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential. Oncotarget. 2016;7:78396-78411 pubmed publisher
  12. Uggenti C, Briant K, Streit A, Thomson S, Koay Y, Baines R, et al. Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model. Dis Model Mech. 2016;9:1317-1328 pubmed
  13. Lee J, Lee I, Chang W, Ahn S, Lim S, Kim H, et al. MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis. Oncotarget. 2016;7:43492-43503 pubmed publisher
  14. Ziegler K, Kerimi A, Poquet L, Williamson G. Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4). Arch Biochem Biophys. 2016;599:3-12 pubmed publisher
  15. Morais Santos F, Granja S, Miranda Gonçalves V, Moreira A, Queirós S, Vilaça J, et al. Targeting lactate transport suppresses in vivo breast tumour growth. Oncotarget. 2015;6:19177-89 pubmed
  16. Zhang J, Gao Q, Zhou Y, Dier U, Hempel N, Hochwald S. Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis. Oncogene. 2016;35:1926-42 pubmed publisher
  17. Kershaw S, Cummings J, Morris K, Tugwood J, Dive C. Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells. BMC Cancer. 2015;15:387 pubmed publisher
  18. Pértega Gomes N, Felisbino S, Massie C, Vizcaíno J, Coelho R, Sandi C, et al. A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy. J Pathol. 2015;236:517-30 pubmed publisher
  19. Valença I, Pértega Gomes N, Vizcaino J, Henrique R, Lopes C, Baltazar F, et al. Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. J Cell Mol Med. 2015;19:723-33 pubmed publisher