This is a Validated Antibody Database (VAD) review about human MCM7, based on 32 published articles (read how Labome selects the articles), using MCM7 antibody in all methods. It is aimed to help Labome visitors find the most suited MCM7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MCM7 synonym: CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS146; PPP1R104; DNA replication licensing factor MCM7; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; protein phosphatase 1, regulatory subunit 104

Santa Cruz Biotechnology
mouse monoclonal (141.2)
  • western blot; human; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology MCM7 antibody (SantaCruz, sc-9966) was used in western blot on human samples at 1:1000 (fig 3b). Nat Commun (2018) ncbi
mouse monoclonal (141.2)
  • western blot; human; 1:2000; loading ...; fig 1d
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz Biotechnology, sc9966) was used in western blot on human samples at 1:2000 (fig 1d). Science (2017) ncbi
mouse monoclonal (141.2)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology MCM7 antibody (SantaCruz, sc-9966) was used in western blot on human samples (fig 3a). Oncogene (2017) ncbi
mouse monoclonal (DCS-141)
  • immunocytochemistry; mouse; fig 6a
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, DCS-141) was used in immunocytochemistry on mouse samples (fig 6a). Cell Death Differ (2017) ncbi
mouse monoclonal (141.2)
  • western blot; mouse; loading ...; fig 4h
In order to test if telomerase reverse transcriptase modulates proliferative vascular remodeling, Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in western blot on mouse samples (fig 4h). Arterioscler Thromb Vasc Biol (2017) ncbi
mouse monoclonal (47DC141)
  • immunocytochemistry; human; loading ...; fig 2d
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology MCM7 antibody (SantaCruz, sc-56324) was used in immunocytochemistry on human samples (fig 2d) and in western blot on human samples (fig 2a). Open Biol (2016) ncbi
mouse monoclonal (141.2)
  • chromatin immunoprecipitation; human; loading ...; fig 7a
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 5c
Santa Cruz Biotechnology MCM7 antibody (SantaCruz, Sc-9966) was used in chromatin immunoprecipitation on human samples (fig 7a), in immunocytochemistry on human samples (fig 5a) and in western blot on human samples (fig 5c). Biol Open (2016) ncbi
mouse monoclonal (141.2)
  • western blot; common platanna; 1:1000; fig 8
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in western blot on common platanna samples at 1:1000 (fig 8). Nat Commun (2016) ncbi
mouse monoclonal (141.2)
  • immunoprecipitation; human; fig 6
  • immunocytochemistry; human; fig 7
  • western blot; human; 1:1000; fig 1
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in immunoprecipitation on human samples (fig 6), in immunocytochemistry on human samples (fig 7) and in western blot on human samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (141.2)
  • western blot; human; 1:1000; fig 5
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz Biotechnology, sc-9966) was used in western blot on human samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (DCS-141)
  • western blot; human; fig 1
In order to analyze G2 checkpoint regulators for hypoxia-induced alterations, Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-65469) was used in western blot on human samples (fig 1). Mol Oncol (2016) ncbi
mouse monoclonal (47DC141)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology MCM7 antibody (SCBT, 47DC141) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (141.2)
  • western blot; human; fig 2
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc9966) was used in western blot on human samples (fig 2). Biochim Biophys Acta (2016) ncbi
mouse monoclonal (47DC141)
  • immunohistochemistry - paraffin section; mouse; fig 8
In order to study hepatocellular carcinoma and ectopic lymphoid structures function as microniches for tumor progenitor cells, Santa Cruz Biotechnology MCM7 antibody (Santa Cruz Biotechnology, sc-56324) was used in immunohistochemistry - paraffin section on mouse samples (fig 8). Nat Immunol (2015) ncbi
mouse monoclonal (141.2)
  • western blot; human; fig 6
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in western blot on human samples (fig 6). Oncogene (2015) ncbi
mouse monoclonal (H-5)
  • immunocytochemistry; mouse
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz Biotechnology, sc-374403) was used in immunocytochemistry on mouse samples . J Cell Biochem (2015) ncbi
mouse monoclonal (141.2)
  • western blot; human; fig 3a
Santa Cruz Biotechnology MCM7 antibody (Santa, 141.2) was used in western blot on human samples (fig 3a). J Biol Chem (2014) ncbi
mouse monoclonal (DCS-141)
  • western blot; human; 1:500; fig 6
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc65469) was used in western blot on human samples at 1:500 (fig 6). Nat Cell Biol (2014) ncbi
mouse monoclonal (141.2)
  • immunocytochemistry; human; 1:200
In order to evaluate diagnostic markers for lung cancer with bronchial brushing specimens, Santa Cruz Biotechnology MCM7 antibody (Santa Cruz Biotechnology, sc-9966) was used in immunocytochemistry on human samples at 1:200. Cancer Cytopathol (2014) ncbi
mouse monoclonal (0.N.194)
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-71550) was used in western blot on human samples (fig 5a). J Invest Dermatol (2014) ncbi
mouse monoclonal (141.2)
  • western blot; human
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in western blot on human samples . FEBS J (2014) ncbi
mouse monoclonal (141.2)
  • western blot; human; 1:1000
Santa Cruz Biotechnology MCM7 antibody (Santa Cruz, sc-9966) was used in western blot on human samples at 1:1000. Nucleic Acids Res (2011) ncbi
Abcam
rabbit monoclonal (EP1974Y)
  • western blot; human; 1:5000; loading ...; fig 4a
Abcam MCM7 antibody (Abcam, ab52489) was used in western blot on human samples at 1:5000 (fig 4a). Nat Commun (2018) ncbi
rabbit monoclonal (EP1974Y)
  • immunohistochemistry - paraffin section; rat; 1:2000; loading ...; fig st11
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig st11
In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam MCM7 antibody (Abcam, ab52489) was used in immunohistochemistry - paraffin section on rat samples at 1:2000 (fig st11) and in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig st11). J Toxicol Pathol (2017) ncbi
rabbit monoclonal (EP1974Y)
  • immunohistochemistry - paraffin section; human; 1:100; fig s8
Abcam MCM7 antibody (Epitomics/Abcam, EP1974Y) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s8). Oncotarget (2016) ncbi
mouse monoclonal (47DC141)
  • western blot; mouse; fig 1d
Abcam MCM7 antibody (Abcam, ab2360) was used in western blot on mouse samples (fig 1d). PLoS Genet (2016) ncbi
rabbit monoclonal (EP1974Y)
  • immunocytochemistry; human
Abcam MCM7 antibody (Abcam, ab52489) was used in immunocytochemistry on human samples . Neoplasia (2014) ncbi
rabbit monoclonal (EP1974Y)
  • western blot; human; fig 2e
Abcam MCM7 antibody (Abcam, ab52489) was used in western blot on human samples (fig 2e). Cell Rep (2014) ncbi
mouse monoclonal (47DC141)
  • immunocytochemistry; human; loading ...; fig 2b
Abcam MCM7 antibody (Abcam, AB2360) was used in immunocytochemistry on human samples (fig 2b). J Invest Dermatol (2014) ncbi
Bethyl
goat polyclonal
  • western blot; human; loading ...; fig 3d
In order to demonstrate a role for CDC6 in cell survival and DNA replication, Bethyl MCM7 antibody (Bethyl Laboratories, A300-128A) was used in western blot on human samples (fig 3d). elife (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig s6a
In order to clarify break-induced telomere synthesis and show that it uses a specialized replisome involved in telomere maintenance, Bethyl MCM7 antibody (Bethyl, A302-584A) was used in immunocytochemistry on human samples (fig s6a). Nature (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (D10A11)
  • western blot; mouse; fig 1d
Cell Signaling Technology MCM7 antibody (Cell Signaling, 3735) was used in western blot on mouse samples (fig 1d). PLoS Genet (2016) ncbi
rabbit monoclonal (D10A11)
  • chromatin immunoprecipitation; human; fig 4
  • immunocytochemistry; human; fig 4c
Cell Signaling Technology MCM7 antibody (Cell Signaling Technology., 3735S) was used in chromatin immunoprecipitation on human samples (fig 4) and in immunocytochemistry on human samples (fig 4c). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology MCM7 antibody (Cell Signaling, 4018) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
Articles Reviewed
  1. Li M, Xu X, Chang C, Zheng L, Shen B, Liu Y. SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun. 2018;9:2706 pubmed publisher
  2. Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed publisher
  3. Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed publisher
  4. He D, Ren B, Liu S, Tan L, Cieply K, Tseng G, et al. Oncogenic activity of amplified miniature chromosome maintenance 8 in human malignancies. Oncogene. 2017;36:3629-3639 pubmed publisher
  5. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  6. Pajalunga D, Franzolin E, Stevanoni M, Zribi S, Passaro N, Gurtner A, et al. A defective dNTP pool hinders DNA replication in cell cycle-reactivated terminally differentiated muscle cells. Cell Death Differ. 2017;24:774-784 pubmed publisher
  7. Endorf E, Qing H, Aono J, Terami N, Doyon G, Hyzny E, et al. Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. Arterioscler Thromb Vasc Biol. 2017;37:301-311 pubmed publisher
  8. Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
  9. Samson A, Ho B, Au A, Schoenwaelder S, Smyth M, Bottomley S, et al. Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells. Open Biol. 2016;6: pubmed
  10. Dilley R, Verma P, Cho N, Winters H, Wondisford A, Greenberg R. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature. 2016;539:54-58 pubmed publisher
  11. Lu F, Wu X, Yin F, Chia Fang Lee C, Yu M, Mihaylov I, et al. Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases. Biol Open. 2016;5:1449-1460 pubmed publisher
  12. Simon A, Sannino V, Costanzo V, Pellegrini L. Structure of human Cdc45 and implications for CMG helicase function. Nat Commun. 2016;7:11638 pubmed publisher
  13. Huang Y, Amin A, Qin Y, Wang Z, Jiang H, Liang L, et al. A Role of hIPI3 in DNA Replication Licensing in Human Cells. PLoS ONE. 2016;11:e0151803 pubmed publisher
  14. Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget. 2016;7:15065-92 pubmed publisher
  15. Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher
  16. Hasvold G, Lund Andersen C, Lando M, Patzke S, Hauge S, Suo Z, et al. Hypoxia-induced alterations of G2 checkpoint regulators. Mol Oncol. 2016;10:764-73 pubmed publisher
  17. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  18. Bai G, Smolka M, Schimenti J. Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS Genet. 2016;12:e1005787 pubmed publisher
  19. Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, et al. Direct non transcriptional role of NF-Y in DNA replication. Biochim Biophys Acta. 2016;1863:673-85 pubmed publisher
  20. Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat Immunol. 2015;16:1235-44 pubmed publisher
  21. Yun J, Song S, Kang J, Park J, Kim H, Han S, et al. Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability. Nucleic Acids Res. 2016;44:558-72 pubmed publisher
  22. Romani B, Shaykh Baygloo N, Aghasadeghi M, Allahbakhshi E. HIV-1 Vpr Protein Enhances Proteasomal Degradation of MCM10 DNA Replication Factor through the Cul4-DDB1[VprBP] E3 Ubiquitin Ligase to Induce G2/M Cell Cycle Arrest. J Biol Chem. 2015;290:17380-9 pubmed publisher
  23. Kanu N, Grönroos E, Martinez P, Burrell R, Yi Goh X, Bartkova J, et al. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015;34:5699-708 pubmed publisher
  24. Nguyen H, Ortega M, Ko M, Marh J, Ward W. ORC4 surrounds extruded chromatin in female meiosis. J Cell Biochem. 2015;116:778-86 pubmed publisher
  25. Quimbaya M, Raspé E, Denecker G, De Craene B, Roelandt R, Declercq W, et al. Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability. Neoplasia. 2014;16:694-709 pubmed publisher
  26. Wu M, Lu W, Santos R, Frattini M, Kelly T. Geminin inhibits a late step in the formation of human pre-replicative complexes. J Biol Chem. 2014;289:30810-21 pubmed publisher
  27. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  28. Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher
  29. Wang J, Xu X, Alontaga A, Chen Y, Liu Y. Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction. Cell Rep. 2014;7:848-58 pubmed publisher
  30. Dumit V, Kuttner V, Käppler J, Piera Velazquez S, Jimenez S, Bruckner Tuderman L, et al. Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts. J Invest Dermatol. 2014;134:2321-2330 pubmed publisher
  31. Kusunoki S, Ishimi Y. Interaction of human minichromosome maintenance protein-binding protein with minichromosome maintenance 2-7. FEBS J. 2014;281:1057-67 pubmed publisher
  32. Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed publisher