This is a Validated Antibody Database (VAD) review about human MAVS, based on 16 published articles (read how Labome selects the articles), using MAVS antibody in all methods. It is aimed to help Labome visitors find the most suited MAVS antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAVS synonym: CARDIF; IPS-1; IPS1; VISA

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (E-3)
  • western blot knockout validation; human; loading ...; fig 6c
Santa Cruz Biotechnology MAVS antibody (Santa, sc166583) was used in western blot knockout validation on human samples (fig 6c). elife (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-3)
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology MAVS antibody (Santa Cruz, sc-166583) was used in western blot knockout validation on human samples (fig 5a). Mol Cell Biol (2017) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 1h
Cell Signaling Technology MAVS antibody (Cell Signaling, 3993) was used in western blot knockout validation on human samples at 1:1000 (fig 1h). Nat Commun (2019) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1h
Cell Signaling Technology MAVS antibody (Cell Signaling, 3993) was used in western blot knockout validation on human samples (fig 1h). PLoS Pathog (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-3)
  • western blot knockout validation; human; loading ...; fig 6c
Santa Cruz Biotechnology MAVS antibody (Santa, sc166583) was used in western blot knockout validation on human samples (fig 6c). elife (2020) ncbi
mouse monoclonal (E-3)
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology MAVS antibody (Santa Cruz, sc-166583) was used in western blot knockout validation on human samples (fig 5a). Mol Cell Biol (2017) ncbi
mouse monoclonal (E-3)
  • western blot; human; loading ...; fig 4e
Santa Cruz Biotechnology MAVS antibody (Santa Cruz, E-3) was used in western blot on human samples (fig 4e). J Virol (2016) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig 4e
Santa Cruz Biotechnology MAVS antibody (Santa Cruz, E-3) was used in western blot on human samples (fig 4e). J Virol (2016) ncbi
mouse monoclonal (E-3)
  • western blot; human
Santa Cruz Biotechnology MAVS antibody (Santa Cruz, sc-166583) was used in western blot on human samples . Sci Rep (2015) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig 2c
Abcam MAVS antibody (Abcam, ab31334) was used in western blot on human samples at 1:5000 (fig 2c). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 5
Abcam MAVS antibody (Abcam, ab31334) was used in western blot on mouse samples at 1:500 (fig 5). Sci Rep (2016) ncbi
Enzo Life Sciences
domestic rabbit polyclonal
  • western blot; human; 1:2000; fig 3
Enzo Life Sciences MAVS antibody (Enzo Life Sciences, AT107) was used in western blot on human samples at 1:2000 (fig 3). Nat Immunol (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology MAVS antibody (Cell Signaling Technology, 3993) was used in western blot on human samples at 1:1000 (fig 1e). Signal Transduct Target Ther (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 1h
Cell Signaling Technology MAVS antibody (Cell Signaling, 3993) was used in western blot knockout validation on human samples at 1:1000 (fig 1h). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig s6c
  • western blot; mouse; loading ...; fig s6a
Cell Signaling Technology MAVS antibody (Cell Signaling, 4983) was used in immunoprecipitation on mouse samples (fig s6c) and in western blot on mouse samples (fig s6a). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s6s
Cell Signaling Technology MAVS antibody (Cell Signaling Technology, 3993) was used in western blot on human samples (fig s6s). Sci Adv (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology MAVS antibody (Cell Signaling, 3993) was used in western blot on human samples (fig 3f). PLoS ONE (2018) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 1h
Cell Signaling Technology MAVS antibody (Cell Signaling, 3993) was used in western blot knockout validation on human samples (fig 1h). PLoS Pathog (2017) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig s5h
  • western blot; mouse; 1:2000; loading ...; fig s5h
In order to describe the mechanism by which FBXW7 stabilizes RigI, Cell Signaling Technology MAVS antibody (Cell Signaling, 4983) was used in immunoprecipitation on mouse samples (fig s5h) and in western blot on mouse samples at 1:2000 (fig s5h). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology MAVS antibody (Cell Signaling, 4983) was used in western blot on mouse samples (fig 4a). Mol Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology MAVS antibody (Cell Signaling, 4983) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
Adipogen
monoclonal (Adri-1)
  • western blot; human; loading ...; fig 1d
Adipogen MAVS antibody (Adipogen, AG-20B-0004-C100) was used in western blot on human samples (fig 1d). Mol Cell Biochem (2019) ncbi
Articles Reviewed
  1. Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
  2. Zhou L, He R, Fang P, Li M, Yu H, Wang Q, et al. Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition. Nat Commun. 2021;12:98 pubmed publisher
  3. Colpitts C, Ridewood S, Schneiderman B, Warne J, Tabata K, Ng C, et al. Hepatitis C virus exploits cyclophilin A to evade PKR. elife. 2020;9: pubmed publisher
  4. Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
  5. Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  6. Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2019;453:187-196 pubmed publisher
  7. Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin F, et al. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses. Sci Adv. 2018;4:eaar2824 pubmed publisher
  8. Ghosh R, Roy S, Franco S. PARP1 depletion induces RIG-I-dependent signaling in human cancer cells. PLoS ONE. 2018;13:e0194611 pubmed publisher
  9. Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, et al. MAVS activates TBK1 and IKK? through TRAFs in NEMO dependent and independent manner. PLoS Pathog. 2017;13:e1006720 pubmed publisher
  10. Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
  11. Choi Y, Shembade N, Parvatiyar K, Balachandran S, Harhaj E. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017;37: pubmed publisher
  12. Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, et al. RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci U S A. 2016;113:9581-6 pubmed publisher
  13. Chan Y, Gack M. A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016;17:523-30 pubmed publisher
  14. Wu H, Shi L, Wang Q, Cheng L, Zhao X, Chen Q, et al. Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells. Sci Rep. 2016;6:19507 pubmed publisher
  15. Hwang K, Choi Y. Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1. J Virol. 2016;90:506-20 pubmed publisher
  16. Schmidt T, Schmid Burgk J, Hornung V. Synthesis of an arrayed sgRNA library targeting the human genome. Sci Rep. 2015;5:14987 pubmed publisher