This is a Validated Antibody Database (VAD) review about human MAP4K4, based on 5 published articles (read how Labome selects the articles), using MAP4K4 antibody in all methods. It is aimed to help Labome visitors find the most suited MAP4K4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAP4K4 synonym: FLH21957; HEL-S-31; HGK; MEKKK4; NIK

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D19H10)
  • western blot knockout validation; human; loading ...; fig 2a
Cell Signaling Technology MAP4K4 antibody (CST, 5146) was used in western blot knockout validation on human samples (fig 2a). Sci Rep (2021) ncbi
Abnova
mouse monoclonal (2D4)
  • immunocytochemistry; bovine; 1:100; fig 3a
In order to elucidate the acquired motility and invasiveness of T. annulata-infected cells, Abnova MAP4K4 antibody (Abnova, H00009448-M01) was used in immunocytochemistry on bovine samples at 1:100 (fig 3a). PLoS Pathog (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D19H10)
  • western blot knockout validation; human; loading ...; fig 2a
Cell Signaling Technology MAP4K4 antibody (CST, 5146) was used in western blot knockout validation on human samples (fig 2a). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 3c
  • western blot; human; 1:300; loading ...; fig 2s1b
Cell Signaling Technology MAP4K4 antibody (Cell Signaling Technology, 3485S) was used in immunoprecipitation on human samples (fig 3c) and in western blot on human samples at 1:300 (fig 2s1b). elife (2020) ncbi
domestic rabbit monoclonal (D19H10)
  • western blot; human; 1:1000; loading ...; fig 2g
Cell Signaling Technology MAP4K4 antibody (Cell Signaling, 5146) was used in western blot on human samples at 1:1000 (fig 2g). elife (2019) ncbi
domestic rabbit monoclonal (D19H10)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology MAP4K4 antibody (Cell signaling, 5146) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
Articles Reviewed
  1. Garcia Garcia S, Rodrigo Faus M, Fonseca N, Manzano S, Gyorffy B, Ocana A, et al. HGK promotes metastatic dissemination in prostate cancer. Sci Rep. 2021;11:12287 pubmed publisher
  2. Kim J, Berrios C, Kim M, SCHADE A, Adelmant G, Yeerna H, et al. STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. elife. 2020;9: pubmed publisher
  3. Fearnley G, Young K, Edgar J, Antrobus R, Hay I, Liang W, et al. The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion. elife. 2019;8: pubmed publisher
  4. Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
  5. Ma M, Baumgartner M. Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton. PLoS Pathog. 2014;10:e1004003 pubmed publisher