This is a Validated Antibody Database (VAD) review about human MAP3K8, based on 2 published articles (read how Labome selects the articles), using MAP3K8 antibody in all methods. It is aimed to help Labome visitors find the most suited MAP3K8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAP3K8 synonym: AURA2; COT; EST; ESTF; MEKK8; TPL2; Tpl-2; c-COT; mitogen-activated protein kinase kinase kinase 8; Ewing sarcoma transformant; augmented in rheumatoid arthritis 2; cot (cancer Osaka thyroid) oncogene; proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; tumor progression locus 2

Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4d
In order to identify and study roles for MAP3K8 in high-grade serous ovarian carcinomas, Cell Signaling Technology MAP3K8 antibody (Cell Signalling, 4491) was used in western blot on human samples at 1:1000 (fig 4d). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology MAP3K8 antibody (Cell Signaling Technology, 4491) was used in western blot on human samples . Carcinogenesis (2014) ncbi
Articles Reviewed
  1. Gruosso T, Garnier C, Abélanet S, Kieffer Y, Lemesre V, Bellanger D, et al. MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas. Nat Commun. 2015;6:8583 pubmed publisher
  2. Kim K, Kim G, Kim J, Yun H, Lim S, Choi H. Interleukin-22 promotes epithelial cell transformation and breast tumorigenesis via MAP3K8 activation. Carcinogenesis. 2014;35:1352-61 pubmed publisher