This is a Validated Antibody Database (VAD) review about human MALT1, based on 11 published articles (read how Labome selects the articles), using MALT1 antibody in all methods. It is aimed to help Labome visitors find the most suited MALT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MALT1 synonym: IMD12; MLT; MLT1; PCASP1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; MALT1 protease; caspase-like protein; mucosa associated lymphoid tissue lymphoma translocation gene 1; paracaspase; paracaspase-1

Knockout validation
Abcam
rabbit monoclonal (EP603Y)
  • western blot knockout validation; human; loading ...; fig 3d
In order to study T cell receptor-induced conjugation of Bcl10 with linear-linked polyubiquitin chains, Abcam MALT1 antibody (Abcam, ab33921) was used in western blot knockout validation on human samples (fig 3d). J Biol Chem (2016) ncbi
Abcam
rabbit monoclonal (EP603Y)
  • western blot; human; loading ...; fig 2a
Abcam MALT1 antibody (Abcam, ab33921) was used in western blot on human samples (fig 2a). PLoS ONE (2017) ncbi
mouse monoclonal (MT1/410)
  • western blot; human; fig 3c
Abcam MALT1 antibody (Abcam, ab178581) was used in western blot on human samples (fig 3c). PLoS ONE (2017) ncbi
rabbit monoclonal (EP603Y)
  • western blot knockout validation; human; loading ...; fig 3d
In order to study T cell receptor-induced conjugation of Bcl10 with linear-linked polyubiquitin chains, Abcam MALT1 antibody (Abcam, ab33921) was used in western blot knockout validation on human samples (fig 3d). J Biol Chem (2016) ncbi
rabbit monoclonal (EP603Y)
  • western blot; human; loading ...; fig 3b
In order to show that CARD14 activates p38 and JNK MAP kinase pathways, Abcam MALT1 antibody (Abcam, ab33921) was used in western blot on human samples (fig 3b). EMBO Rep (2016) ncbi
rabbit monoclonal (EP603Y)
  • immunocytochemistry; human; loading ...; fig 3d
Abcam MALT1 antibody (Abcam, EP603Y) was used in immunocytochemistry on human samples (fig 3d). Nat Commun (2015) ncbi
rabbit monoclonal (EP603Y)
  • western blot; human; loading ...; fig 1c
Abcam MALT1 antibody (Abcam, ab33921) was used in western blot on human samples (fig 1c). PLoS ONE (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-12)
  • western blot; human; 1:1000; loading ...; fig 2c
Santa Cruz Biotechnology MALT1 antibody (Santa, B-12) was used in western blot on human samples at 1:1000 (fig 2c). Front Immunol (2018) ncbi
mouse monoclonal (B-12)
  • western blot; human; 1:1000; fig 1
Santa Cruz Biotechnology MALT1 antibody (Santa Cruz Biotechnology, B-12) was used in western blot on human samples at 1:1000 (fig 1). J Cell Sci (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology MALT1 antibody (Cell Signaling Technology, 2494) was used in western blot on mouse samples at 1:1000 (fig 5a). Nat Commun (2019) ncbi
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1a
  • immunoprecipitation; mouse; loading ...; fig 1b
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology MALT1 antibody (Cell Signaling, 2494S) was used in immunoprecipitation on human samples (fig 1a), in western blot on human samples (fig 1a), in immunoprecipitation on mouse samples (fig 1b) and in western blot on mouse samples (fig 1b). J Clin Invest (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 7
Cell Signaling Technology MALT1 antibody (Cell Signaling, 2494s) was used in western blot on mouse samples at 1:1000 (fig 7). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology MALT1 antibody (Cell Signaling, 2494) was used in western blot on mouse samples (fig 5b). J Immunol (2016) ncbi
Articles Reviewed
  1. Cho J, Xu Z, Parthasarathy U, Drashansky T, Helm E, Zuniga A, et al. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019;10:701 pubmed publisher
  2. Seeholzer T, Kurz S, Schlauderer F, Woods S, Gehring T, Widmann S, et al. BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation. Front Immunol. 2018;9:2695 pubmed publisher
  3. Ginster S, Bardet M, Unterreiner A, Malinverni C, Renner F, Lam S, et al. Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation. PLoS ONE. 2017;12:e0169026 pubmed publisher
  4. Yang Y, Yang C, Chan W, Wang Z, Deibel K, Pomerantz J. Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling. J Biol Chem. 2016;291:25921-25936 pubmed
  5. Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. J Clin Invest. 2016;126:3837-3851 pubmed publisher
  6. Afonina I, Van Nuffel E, Baudelet G, Driege Y, Kreike M, Staal J, et al. The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes. EMBO Rep. 2016;17:914-27 pubmed publisher
  7. Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed publisher
  8. Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed publisher
  9. Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  10. Klein T, Fung S, Renner F, Blank M, Dufour A, Kang S, et al. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nat Commun. 2015;6:8777 pubmed publisher
  11. Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed publisher