This is a Validated Antibody Database (VAD) review about human MAGEA1, based on 6 published articles (read how Labome selects the articles), using MAGEA1 antibody in all methods. It is aimed to help Labome visitors find the most suited MAGEA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAGEA1 synonym: CT1.1; MAGE1; melanoma-associated antigen 1; MAGE-1 antigen; antigen MZ2-E; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; melanoma antigen MAGE-1; melanoma antigen family A 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma-associated antigen MZ2-E

Invitrogen
mouse monoclonal (MA454)
  • flow cytometry; human; fig 2a
In order to identify NFATc2 as a regulator of human melanoma dedifferentiation, Invitrogen MAGEA1 antibody (Life Technologies, MA5-11338) was used in flow cytometry on human samples (fig 2a). Oncogene (2016) ncbi
mouse monoclonal (6C1)
  • western blot; human; 1:200; fig 1
In order to investigate the effect of SGI-110 on cancer testis antigen gene-regulated expression, Invitrogen MAGEA1 antibody (Invitrogen, 35-6300) was used in western blot on human samples at 1:200 (fig 1). Leuk Res (2014) ncbi
mouse monoclonal (6C1)
  • western blot; human; 1:250; fig s3
In order to investigate the role of CT16 in melanoma cell survival, Invitrogen MAGEA1 antibody (Thermo Fischer Scientific, 6C1) was used in western blot on human samples at 1:250 (fig s3). PLoS ONE (2012) ncbi
mouse monoclonal (MA454)
  • immunohistochemistry - paraffin section; human; fig 3
In order to identify and evaluate cancer-germline genes for therapeutic vaccine targets in various pediatric solid tumors, Invitrogen MAGEA1 antibody (Zymed, MA454) was used in immunohistochemistry - paraffin section on human samples (fig 3). Int J Cancer (2007) ncbi
Santa Cruz Biotechnology
mouse monoclonal (6A111)
  • western blot; human; 1:1000; fig 5
Santa Cruz Biotechnology MAGEA1 antibody (Santa Cruz, sc71537) was used in western blot on human samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (6C1)
  • immunohistochemistry - paraffin section; human; 1:100
  • immunoprecipitation; human
  • western blot; human
Santa Cruz Biotechnology MAGEA1 antibody (Santa Cruz Biotechnology, sc-20034) was used in immunohistochemistry - paraffin section on human samples at 1:100, in immunoprecipitation on human samples and in western blot on human samples . Oncogene (2014) ncbi
Articles Reviewed
  1. Gao Y, Mutter Rottmayer E, Greenwalt A, Goldfarb D, Yan F, Yang Y, et al. A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. Nat Commun. 2016;7:12105 pubmed publisher
  2. Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed publisher
  3. Srivastava P, Paluch B, Matsuzaki J, James S, Collamat Lai G, Karbach J, et al. Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells and xenografts. Leuk Res. 2014;38:1332-41 pubmed publisher
  4. Wong P, Yeoh C, Ahmad A, Chelala C, Gillett C, Speirs V, et al. Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer. Oncogene. 2014;33:4579-88 pubmed publisher
  5. Nylund C, Rappu P, Pakula E, Heino A, Laato L, Elo L, et al. Melanoma-associated cancer-testis antigen 16 (CT16) regulates the expression of apoptotic and antiapoptotic genes and promotes cell survival. PLoS ONE. 2012;7:e45382 pubmed publisher
  6. Jacobs J, Brasseur F, Hulsbergen van de Kaa C, van de Rakt M, Figdor C, Adema G, et al. Cancer-germline gene expression in pediatric solid tumors using quantitative real-time PCR. Int J Cancer. 2007;120:67-74 pubmed