This is a Validated Antibody Database (VAD) review about human MAFA, based on 8 published articles (read how Labome selects the articles), using MAFA antibody in all methods. It is aimed to help Labome visitors find the most suited MAFA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAFA synonym: INSDM; RIPE3b1; hMafA; transcription factor MafA; pancreatic beta-cell-specific transcriptional activator; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A

Abcam
rabbit polyclonal
  • immunocytochemistry; mouse; loading ...; fig 3c
  • western blot; mouse; loading ...; fig 3f
Abcam MAFA antibody (Abcam, ab26405) was used in immunocytochemistry on mouse samples (fig 3c) and in western blot on mouse samples (fig 3f). J Clin Invest (2019) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 5c
Abcam MAFA antibody (abcam, ab17976) was used in immunohistochemistry - paraffin section on mouse samples (fig 5c). J Biol Chem (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 4h
In order to demonstrate that dCas9 activator controls human pluripotent stem cell differentiation into endodermal lineages, Abcam MAFA antibody (Abcam, AB26405) was used in immunocytochemistry on human samples at 1:500 (fig 4h). Stem Cell Reports (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig s4h
  • western blot; human; fig s4g
In order to identify analogs of harmine as a new class of human beta cell mitogenic compounds and identify the pathways they activate, Abcam MAFA antibody (Abcam, Ab26405) was used in immunocytochemistry on human samples (fig s4h) and in western blot on human samples (fig s4g). Nat Med (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Abcam MAFA antibody (Abcam, ab26405) was used in immunohistochemistry - paraffin section on human samples . PLoS ONE (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-6)
  • western blot; mouse; 1:500; loading ...; fig 2g
Santa Cruz Biotechnology MAFA antibody (Santa Cruz, sc-390491) was used in western blot on mouse samples at 1:500 (fig 2g). FASEB J (2017) ncbi
Novus Biologicals
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s1c
Novus Biologicals MAFA antibody (Novus Biologicals, NBP1-00121) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig s1c). Diabetes (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 1f
Novus Biologicals MAFA antibody (Novus, NBP1-00121) was used in western blot on mouse samples at 1:1000 (fig 1f). Mol Endocrinol (2015) ncbi
Articles Reviewed
  1. Bartolomé A, Zhu C, Sussel L, Pajvani U. Notch signaling dynamically regulates adult β cell proliferation and maturity. J Clin Invest. 2019;129:268-280 pubmed publisher
  2. Wei J, Ding D, Wang T, Liu Q, Lin Y. MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1. FASEB J. 2017;31:5184-5195 pubmed publisher
  3. Spaeth J, Gupte M, Perelis M, Yang Y, CYPHERT H, Guo S, et al. Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning. Diabetes. 2017;66:2830-2839 pubmed publisher
  4. Roth Flach R, Danai L, DiStefano M, Kelly M, Menendez L, Jurczyk A, et al. Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia. J Biol Chem. 2016;291:16221-30 pubmed publisher
  5. Galloway J, Bethea M, Liu Y, Underwood R, Mobley J, Hunter C. SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes. Mol Endocrinol. 2015;29:1774-86 pubmed publisher
  6. Balboa D, Weltner J, Eurola S, Trokovic R, Wartiovaara K, Otonkoski T. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation. Stem Cell Reports. 2015;5:448-59 pubmed publisher
  7. Wang P, Alvarez Perez J, Felsenfeld D, Liu H, Sivendran S, Bender A, et al. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication. Nat Med. 2015;21:383-8 pubmed publisher
  8. Bonnavion R, Jaafar R, Kerr Conte J, Assade F, Van Stralen E, Leteurtre E, et al. Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes. PLoS ONE. 2013;8:e72194 pubmed publisher