This is a Validated Antibody Database (VAD) review about human MAD2L2, based on 4 published articles (read how Labome selects the articles), using MAD2L2 antibody in all methods. It is aimed to help Labome visitors find the most suited MAD2L2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MAD2L2 synonym: FANCV; MAD2B; POLZ2; REV7; mitotic spindle assembly checkpoint protein MAD2B; MAD2 (mitotic arrest deficient, yeast, homolog)-like 2; MAD2 mitotic arrest deficient-like 2; MAD2-like protein 2; REV7 homolog; hREV7; mitotic arrest deficient 2-like protein 2; mitotic arrest deficient homolog-like 2; polymerase (DNA-directed), zeta 2, accessory subunit

Knockout validation
Abcam
rabbit monoclonal (EPR13657)
  • western blot knockout validation; mouse; loading ...; fig 1f
Abcam MAD2L2 antibody (Abcam, ab180579) was used in western blot knockout validation on mouse samples (fig 1f). Nature (2018) ncbi
Abcam
rabbit monoclonal (EPR13657)
  • western blot knockout validation; mouse; loading ...; fig 1f
Abcam MAD2L2 antibody (Abcam, ab180579) was used in western blot knockout validation on mouse samples (fig 1f). Nature (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (14)
  • western blot; mouse; 1:500; fig 3
In order to report the role of MAD2L2 in DNA repair at mammalian telomeres, Santa Cruz Biotechnology MAD2L2 antibody (Santa Cruz, sc135977) was used in western blot on mouse samples at 1:500 (fig 3). Nature (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1200; fig 4d
Proteintech Group MAD2L2 antibody (ProteinTech, 12683-1-AP) was used in western blot on human samples at 1:1200 (fig 4d). Nucleic Acids Res (2015) ncbi
BD Biosciences
mouse monoclonal (14/MAD2B/Rev7)
  • western blot; mouse; fig s3
BD Biosciences MAD2L2 antibody (BD Biosciences, 612266) was used in western blot on mouse samples (fig s3). Nature (2015) ncbi
Articles Reviewed
  1. Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, et al. 53BP1-RIF1-shieldin counteracts DSB resection through CST- and PolĪ±-dependent fill-in. Nature. 2018;560:112-116 pubmed publisher
  2. Xu G, Chapman J, Brandsma I, Yuan J, Mistrik M, Bouwman P, et al. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015;521:541-544 pubmed publisher
  3. Boersma V, Moatti N, Segura Bayona S, Peuscher M, van der Torre J, Wevers B, et al. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. Nature. 2015;521:537-540 pubmed publisher
  4. Tomida J, Takata K, Lange S, Schibler A, Yousefzadeh M, Bhetawal S, et al. REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ?. Nucleic Acids Res. 2015;43:1000-11 pubmed publisher