This is a Validated Antibody Database (VAD) review about human LRPPRC, based on 9 published articles (read how Labome selects the articles), using LRPPRC antibody in all methods. It is aimed to help Labome visitors find the most suited LRPPRC antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LRPPRC synonym: CLONE-23970; GP130; LRP130; LSFC; leucine-rich PPR motif-containing protein, mitochondrial; 130 kDa leucine-rich protein; LRP 130; leucine-rich PPR-motif containing; mitochondrial leucine-rich PPR motif-containing protein

Santa Cruz Biotechnology
mouse monoclonal (F-7)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology LRPPRC antibody (SantaCruz, sc-166178) was used in western blot on human samples (fig 2a). Open Biol (2016) ncbi
mouse monoclonal (F-7)
  • western blot; human
Santa Cruz Biotechnology LRPPRC antibody (Santa Cruz, SC166178) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (F-7)
  • western blot; mouse; fig 1
Santa Cruz Biotechnology LRPPRC antibody (Santa Cruz, sc-166178) was used in western blot on mouse samples (fig 1). Mol Carcinog (2015) ncbi
mouse monoclonal (F-7)
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology LRPPRC antibody (Santa Cruz Biotechnology, SC166178) was used in immunoprecipitation on human samples , in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2014) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Proteintech Group LRPPRC antibody (Proteintech, 21175-1-AP) was used in western blot on human samples (fig 3c). Proc Natl Acad Sci U S A (2018) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; fig 4e
Proteintech Group LRPPRC antibody (Proteintech, 21175-1-AP) was used in immunoprecipitation on mouse samples (fig 4e). Nat Biotechnol (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 9f
In order to study the role of O-linked N-acetylglucosamine transferase in mitochondria, Abcam LRPPRC antibody (Abcam, ab97505) was used in western blot on human samples at 1:1000 (fig 9f). J Biol Chem (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 2a
Abcam LRPPRC antibody (Abcam, ab97505) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2a). Oncotarget (2015) ncbi
Invitrogen
rabbit polyclonal
  • immunoprecipitation; human
In order to study the interaction between BRCA1 tumor suppressor and inositol 1,4,5-trisphosphate receptors and its effect on apoptotic calcium release, Invitrogen LRPPRC antibody (Thermo Scientific, PA5-22034) was used in immunoprecipitation on human samples . J Biol Chem (2015) ncbi
Articles Reviewed
  1. Liang K, Li N, Wang X, Dai J, Liu P, Wang C, et al. Cryo-EM structure of human mitochondrial trifunctional protein. Proc Natl Acad Sci U S A. 2018;115:7039-7044 pubmed publisher
  2. Sacoman J, Dagda R, Burnham Marusich A, Dagda R, Berninsone P. Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells. J Biol Chem. 2017;292:4499-4518 pubmed publisher
  3. Samson A, Ho B, Au A, Schoenwaelder S, Smyth M, Bottomley S, et al. Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells. Open Biol. 2016;6: pubmed
  4. Liang X, Shen W, Sun H, Migawa M, Vickers T, Crooke S. Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames. Nat Biotechnol. 2016;34:875-80 pubmed publisher
  5. Yang M, Zhao H, Guo L, Zhang Q, Zhao L, Bai S, et al. Autophagy-based survival prognosis in human colorectal carcinoma. Oncotarget. 2015;6:7084-103 pubmed
  6. Hedgepeth S, Garcia M, Wagner L, Rodriguez A, Chintapalli S, Snyder R, et al. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. J Biol Chem. 2015;290:7304-13 pubmed publisher
  7. Zou J, Li W, Misra A, Yue F, Song K, Chen Q, et al. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015;290:7269-79 pubmed publisher
  8. Jiang X, Zhong W, Huang H, He H, Jiang F, Chen Y, et al. Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients. Mol Carcinog. 2015;54:1194-204 pubmed publisher
  9. Zou J, Yue F, Li W, Song K, Jiang X, Yi J, et al. Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin. PLoS ONE. 2014;9:e94903 pubmed publisher