This is a Validated Antibody Database (VAD) review about human LRP5, based on 6 published articles (read how Labome selects the articles), using LRP5 antibody in all methods. It is aimed to help Labome visitors find the most suited LRP5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LRP5 synonym: BMND1; EVR1; EVR4; HBM; LR3; LRP-5; LRP-7; LRP7; OPPG; OPS; OPTA1; PCLD4; VBCH2

Santa Cruz Biotechnology
mouse monoclonal (B-9)
  • immunocytochemistry; human; 1:100; loading ...; fig 6c
Santa Cruz Biotechnology LRP5 antibody (Santa, sc390267) was used in immunocytochemistry on human samples at 1:100 (fig 6c). Oncogene (2019) ncbi
Abcam
domestic goat polyclonal
  • western blot; human; 1:50; loading ...; fig 6g
Abcam LRP5 antibody (Abcam, ab36121) was used in western blot on human samples at 1:50 (fig 6g). Nat Commun (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D80F2)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology LRP5 antibody (CST, 5731) was used in western blot on mouse samples at 1:1000 (fig 4b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D80F2)
  • western blot; rat; loading ...; fig 4a
Cell Signaling Technology LRP5 antibody (Cell Signaling, D80F2) was used in western blot on rat samples (fig 4a). Biomed Pharmacother (2018) ncbi
domestic rabbit monoclonal (D80F2)
  • western blot; human; 1:1000; loading ...; fig s6f
Cell Signaling Technology LRP5 antibody (Cell signaling, 5731S) was used in western blot on human samples at 1:1000 (fig s6f). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D23F7)
  • immunoprecipitation; human
  • western blot; human
Cell Signaling Technology LRP5 antibody (Cell Signaling Technology, D23F7) was used in immunoprecipitation on human samples and in western blot on human samples . Cell Mol Life Sci (2014) ncbi
Articles Reviewed
  1. van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
  2. Ji Q, Xu X, Kang L, Xu Y, Xiao J, Goodman S, et al. Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis. Nat Commun. 2019;10:313 pubmed publisher
  3. Wang H, Deng G, Ai M, Xu Z, Mou T, Yu J, et al. Hsp90ab1 stabilizes LRP5 to promote epithelial-mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression. Oncogene. 2019;38:1489-1507 pubmed publisher
  4. Chen Z, Li Y, Jiang G, Yang C, Wang Y, Wang X, et al. Knockdown of LRP6 activates Drp1 to inhibit survival of cardiomyocytes during glucose deprivation. Biomed Pharmacother. 2018;103:1408-1414 pubmed publisher
  5. Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed publisher
  6. Knoblich K, Wang H, Sharma C, Fletcher A, Turley S, Hemler M. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits ?-catenin degradation. Cell Mol Life Sci. 2014;71:1305-14 pubmed publisher