This is a Validated Antibody Database (VAD) review about human LOXL2, based on 6 published articles (read how Labome selects the articles), using LOXL2 antibody in all methods. It is aimed to help Labome visitors find the most suited LOXL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOXL2 synonym: LOR; LOR2; WS9-14; lysyl oxidase homolog 2; lysyl oxidase related 2; lysyl oxidase-like 2 delta e13; lysyl oxidase-like 2 protein; lysyl oxidase-like protein 2; lysyl oxidase-related protein 2; lysyl oxidase-related protein WS9-14

Knockout validation
Abcam
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 6a
  • western blot knockout validation; mouse; 1:500; loading ...; fig s3f
Abcam LOXL2 antibody (Abcam, ab96233) was used in western blot on human samples at 1:500 (fig 6a) and in western blot knockout validation on mouse samples at 1:500 (fig s3f). Nat Commun (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:1500; loading ...; fig s3c
Abcam LOXL2 antibody (Abcam, ab96233) was used in western blot on human samples at 1:1500 (fig s3c). EBioMedicine (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 6a
  • western blot knockout validation; mouse; 1:500; loading ...; fig s3f
Abcam LOXL2 antibody (Abcam, ab96233) was used in western blot on human samples at 1:500 (fig 6a) and in western blot knockout validation on mouse samples at 1:500 (fig s3f). Nat Commun (2016) ncbi
rabbit monoclonal (EPR12733)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 8b
Abcam LOXL2 antibody (Abcam, ab179810) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 8b). Mol Med Rep (2016) ncbi
R&D Systems
goat polyclonal
  • western blot; mouse; fig 5b
In order to demonstrate of role for LOXL2 in tumor progression, R&D Systems LOXL2 antibody (R&D Systems, AF2639) was used in western blot on mouse samples (fig 5b). Oncogene (2017) ncbi
goat polyclonal
  • western blot; human; fig 1
R&D Systems LOXL2 antibody (R&D, AF2639) was used in western blot on human samples (fig 1). J Cell Mol Med (2016) ncbi
GeneTex
rabbit polyclonal
  • western blot; human; 1:1000
GeneTex LOXL2 antibody (GeneTex, GTX105085) was used in western blot on human samples at 1:1000. Tissue Eng Part A (2012) ncbi
Articles Reviewed
  1. Fregni G, Quinodoz M, Möller E, Vuille J, Galland S, Fusco C, et al. Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis. EBioMedicine. 2018;29:128-145 pubmed publisher
  2. Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed publisher
  3. Peng D, Ungewiss C, Tong P, Byers L, Wang J, Canales J, et al. ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis. Oncogene. 2017;36:1925-1938 pubmed publisher
  4. Wu L, Zhang Y, Zhu Y, Cong Q, Xiang Y, Fu L. The effect of LOXL2 in hepatocellular carcinoma. Mol Med Rep. 2016;14:1923-32 pubmed publisher
  5. de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed publisher
  6. Jung I, Park J, Kim J, Jeon D, Choi S, Cho K, et al. Novel application of human periodontal ligament stem cells and water-soluble chitin for collagen tissue regeneration: in vitro and in vivo investigations. Tissue Eng Part A. 2012;18:643-53 pubmed publisher