This is a Validated Antibody Database (VAD) review about human LMNB2, based on 25 published articles (read how Labome selects the articles), using LMNB2 antibody in all methods. It is aimed to help Labome visitors find the most suited LMNB2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LMNB2 synonym: EPM9; LAMB2; LMN2

Invitrogen
mouse monoclonal (E-3)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5a
Invitrogen LMNB2 antibody (Thermo Fisher, 33-2100) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5a). Invest Ophthalmol Vis Sci (2022) ncbi
mouse monoclonal (E-3)
  • western blot; mouse; 1:500; loading ...; fig 3i
  • western blot; human; 1:500; fig 3h
Invitrogen LMNB2 antibody (ThermoFisher, 33-2100) was used in western blot on mouse samples at 1:500 (fig 3i) and in western blot on human samples at 1:500 (fig 3h). elife (2021) ncbi
mouse monoclonal (LN43)
  • western blot; hamsters; loading ...; fig s19a
In order to propose that local stresses applied to integrins propagate from the tensed actin cytoskeleton to the LINC complex and then through lamina-chromatin interactions to directly stretch chromatin and upregulate transcription, Invitrogen LMNB2 antibody (Thermo Fisher, MA1-06104) was used in western blot on hamsters samples (fig s19a). Nat Mater (2016) ncbi
mouse monoclonal (E-3)
  • immunocytochemistry; rat; 1:100; fig 1
  • western blot; rat; 1:1000; fig 1
In order to elucidate neuropathic pain and the critical role of intracellular mGluR5, Invitrogen LMNB2 antibody (Invitrogen, 33-2100) was used in immunocytochemistry on rat samples at 1:100 (fig 1) and in western blot on rat samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (E-3)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Invitrogen LMNB2 antibody (INVITROGEN, E-3) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (E-3)
  • immunohistochemistry; mouse; 1:100
  • western blot; mouse; 1:400
In order to investigate the role of B-type lamins in the maintenance of nuclear integrity of keratinocytes, Invitrogen LMNB2 antibody (Invitrogen, 33-2100) was used in immunohistochemistry on mouse samples at 1:100 and in western blot on mouse samples at 1:400. Mol Cell Biol (2014) ncbi
mouse monoclonal (E-3)
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
In order to assess functional redundancy of lamin B1 and B2 by way of a reciprocal knock-in mice, Invitrogen LMNB2 antibody (Invitrogen, 33-2100) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples . Mol Biol Cell (2014) ncbi
mouse monoclonal (E-3)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 6
  • western blot; mouse; 1:400; fig 1
In order to study the effects of B-type lamins farnesylation, Invitrogen LMNB2 antibody (Invitrogen, 33-2100) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6) and in western blot on mouse samples at 1:400 (fig 1). Proc Natl Acad Sci U S A (2013) ncbi
mouse monoclonal (E-3)
  • immunohistochemistry; rat; 1:100; fig 1
  • western blot; rat; 1:100; fig 5
In order to study the expression patterns of lamin subtypes in the adult rat retina, Invitrogen LMNB2 antibody (Invitrogen, 33-2100) was used in immunohistochemistry on rat samples at 1:100 (fig 1) and in western blot on rat samples at 1:100 (fig 5). Histochem Cell Biol (2011) ncbi
Abcam
domestic rabbit monoclonal (EPR9701(B))
  • immunohistochemistry; human; loading ...; fig 1d
  • western blot; human; 1:100; loading ...; fig 4a, 4b
Abcam LMNB2 antibody (Abcam, ab151735) was used in immunohistochemistry on human samples (fig 1d) and in western blot on human samples at 1:100 (fig 4a, 4b). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EPR9701(B))
  • immunocytochemistry; mouse; 1:250; loading ...; fig s5
Abcam LMNB2 antibody (Abcam, ab151735) was used in immunocytochemistry on mouse samples at 1:250 (fig s5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR9701(B))
  • western blot; human; fig 1b
Abcam LMNB2 antibody (Abcam, ab151735) was used in western blot on human samples (fig 1b). J Cancer (2016) ncbi
mouse monoclonal (LN43)
  • western blot; human; fig 3
Abcam LMNB2 antibody (Abcam, ab8983) was used in western blot on human samples (fig 3). Nature (2015) ncbi
mouse monoclonal (LN43)
  • immunocytochemistry; human; 1:500; fig s4
Abcam LMNB2 antibody (Abcam, ab8983) was used in immunocytochemistry on human samples at 1:500 (fig s4). Mol Biol Cell (2015) ncbi
domestic rabbit monoclonal (EPR9701(B))
  • immunocytochemistry; human; 1:500; loading ...; fig 4B
  • western blot; human; 1:500; loading ...; fig 5
Abcam LMNB2 antibody (Abcam, ab151735) was used in immunocytochemistry on human samples at 1:500 (fig 4B) and in western blot on human samples at 1:500 (fig 5). Mol Hum Reprod (2015) ncbi
mouse monoclonal (LN43)
  • western blot; human
In order to identify the unique SDS-PAGE pattern of nuclear proteasomes, Abcam LMNB2 antibody (Abcam, ab8983) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (LN43)
  • immunocytochemistry; human
  • immunohistochemistry; human
  • western blot; human
Abcam LMNB2 antibody (Abcam, LN43) was used in immunocytochemistry on human samples , in immunohistochemistry on human samples and in western blot on human samples . Oncogenesis (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (LN43)
  • western blot; mouse; 1:1000; loading ...; fig s4b
Santa Cruz Biotechnology LMNB2 antibody (Santa Cruz Biotechnology, sc-56146) was used in western blot on mouse samples at 1:1000 (fig s4b). J Cell Biol (2017) ncbi
mouse monoclonal (X223)
  • western blot; human; 1:500; loading ...; fig 8a
Santa Cruz Biotechnology LMNB2 antibody (Santa Cruz, sc-56147) was used in western blot on human samples at 1:500 (fig 8a). Development (2017) ncbi
mouse monoclonal (F-8)
  • western blot; human; fig s11
In order to identify an atheroprotective role for circular RNAs, Santa Cruz Biotechnology LMNB2 antibody (Santa Cruz, sc-377379) was used in western blot on human samples (fig s11). Nat Commun (2016) ncbi
mouse monoclonal (X223)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology LMNB2 antibody (SCBT, X223) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (LN43)
  • western blot; human; fig 1
Santa Cruz Biotechnology LMNB2 antibody (santa cruz, sc-56146) was used in western blot on human samples (fig 1). Carcinogenesis (2015) ncbi
mouse monoclonal (X223)
  • immunocytochemistry; Xenopus laevis; 1:25; fig 1
Santa Cruz Biotechnology LMNB2 antibody (santa Cruz, sc-56147) was used in immunocytochemistry on Xenopus laevis samples at 1:25 (fig 1). Protoplasma (2016) ncbi
mouse monoclonal (X223)
  • western blot; Xenopus laevis; loading ...; fig S8
Santa Cruz Biotechnology LMNB2 antibody (Santa Cruz, sc-56147) was used in western blot on Xenopus laevis samples (fig S8). Nat Commun (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8P3U)
  • western blot; human; 1:1000; loading ...; fig 4f
Cell Signaling Technology LMNB2 antibody (Cell Signaling, 12255) was used in western blot on human samples at 1:1000 (fig 4f). Nature (2018) ncbi
domestic rabbit monoclonal (D8P3U)
  • western blot; human; loading ...; fig 1h
  • western blot; rat; loading ...; fig 3g
  • western blot; mouse; loading ...; fig 2e
Cell Signaling Technology LMNB2 antibody (Cell signaling, 12255) was used in western blot on human samples (fig 1h), in western blot on rat samples (fig 3g) and in western blot on mouse samples (fig 2e). Biochem Pharmacol (2015) ncbi
Articles Reviewed
  1. Müller B, Serafin F, Laucke L, Rheinhard W, Wimmer T, Stieger K. Characterization of Double-Strand Break Repair Protein Ku80 Location Within the Murine Retina. Invest Ophthalmol Vis Sci. 2022;63:22 pubmed publisher
  2. Dong C, Jiang T, Yin H, Song H, Zhang Y, Geng H, et al. LMNB2 promotes the progression of colorectal cancer by silencing p21 expression. Cell Death Dis. 2021;12:331 pubmed publisher
  3. Chen X, Yao H, Kashif M, Revêchon G, Eriksson M, Hu J, et al. A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells. elife. 2021;10: pubmed publisher
  4. Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed publisher
  5. Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed publisher
  6. Rauschenberger V, Bernkopf D, Krenn S, Jalal K, Heller J, Behrens J, et al. The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning. Development. 2017;144:2234-2247 pubmed publisher
  7. Tajik A, Zhang Y, Wei F, Sun J, Jia Q, Zhou W, et al. Transcription upregulation via force-induced direct stretching of chromatin. Nat Mater. 2016;15:1287-1296 pubmed publisher
  8. Holdt L, Stahringer A, Sass K, Pichler G, Kulak N, Wilfert W, et al. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans. Nat Commun. 2016;7:12429 pubmed publisher
  9. Tsichlaki E, FitzHarris G. Nucleus downscaling in mouse embryos is regulated by cooperative developmental and geometric programs. Sci Rep. 2016;6:28040 pubmed publisher
  10. Xu L, Liao W, Lu Q, Li C, Yuan Y, Xu Z, et al. ANG Promotes Proliferation and Invasion of the Cell of Lung Squamous Carcinoma by Directly Up-Regulating HMGA2. J Cancer. 2016;7:862-71 pubmed publisher
  11. Vincent K, Cornea V, Jong Y, Laferriere A, Kumar N, Mickeviciute A, et al. Intracellular mGluR5 plays a critical role in neuropathic pain. Nat Commun. 2016;7:10604 pubmed publisher
  12. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  13. Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed publisher
  14. Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper D. Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence. Carcinogenesis. 2015;36:1263-74 pubmed publisher
  15. Dubińska Magiera M, Chmielewska M, Kozioł K, Machowska M, Hutchison C, Goldberg M, et al. Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability. Protoplasma. 2016;253:943-56 pubmed publisher
  16. Eibauer M, Pellanda M, Turgay Y, Dubrovsky A, Wild A, Medalia O. Structure and gating of the nuclear pore complex. Nat Commun. 2015;6:7532 pubmed publisher
  17. Mackay D, Ullman K. ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission. Mol Biol Cell. 2015;26:2217-26 pubmed publisher
  18. Elkhatib R, Longepied G, Paci M, Achard V, Grillo J, Levy N, et al. Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform. Mol Hum Reprod. 2015;21:225-36 pubmed publisher
  19. Li J, Wan Y, Na S, Liu X, Dong G, Yang Z, et al. Sex-dependent regulation of hepatic CYP3A by growth hormone: Roles of HNF6, C/EBPα, and RXRα. Biochem Pharmacol. 2015;93:92-103 pubmed publisher
  20. Jung H, Tatar A, Tu Y, Nobumori C, Yang S, Goulbourne C, et al. An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin. Mol Cell Biol. 2014;34:4534-44 pubmed publisher
  21. Pitcher D, de Mattos Shipley K, Wang Z, Tzortzis K, Goudevenou K, Flynn H, et al. Nuclear proteasomes carry a constitutive posttranslational modification which derails SDS-PAGE (but not CTAB-PAGE). Biochim Biophys Acta. 2014;1844:2222-8 pubmed publisher
  22. Lee J, Tu Y, Tatar A, Wu D, Nobumori C, Jung H, et al. Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. Mol Biol Cell. 2014;25:1666-75 pubmed publisher
  23. Kuga T, Nie H, Kazami T, Satoh M, Matsushita K, Nomura F, et al. Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. Oncogenesis. 2014;3:e94 pubmed publisher
  24. Jung H, Nobumori C, Goulbourne C, Tu Y, Lee J, Tatar A, et al. Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration. Proc Natl Acad Sci U S A. 2013;110:E1923-32 pubmed publisher
  25. Wakabayashi T, Mori T, Hirahara Y, Koike T, Kubota Y, Takamori Y, et al. Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina. Histochem Cell Biol. 2011;136:427-36 pubmed publisher