This is a Validated Antibody Database (VAD) review about human LLGL2, based on 3 published articles (read how Labome selects the articles), using LLGL2 antibody in all methods. It is aimed to help Labome visitors find the most suited LLGL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LLGL2 synonym: HGL; Hugl-2; LGL2; lethal(2) giant larvae protein homolog 2; human giant larvae homolog; lethal giant larvae homolog 2, scribble cell polarity complex component

Abnova
mouse monoclonal (4G2)
  • western blot; human; loading ...; fig 3b
In order to investigate the role of CRB3 downregulation in maintaining breast cancer stem cells, Abnova LLGL2 antibody (Abnova, H00003993-M06) was used in western blot on human samples (fig 3b). Oncogenesis (2017) ncbi
mouse monoclonal (4G2)
  • immunocytochemistry; human; 1:200; loading ...; fig s3c
  • western blot; human; loading ...; fig 9a
Abnova LLGL2 antibody (Abnova, H00003993-M06) was used in immunocytochemistry on human samples at 1:200 (fig s3c) and in western blot on human samples (fig 9a). J Cell Biol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-4)
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 1d
In order to elucidate the contribution of Scribble 1 to neural tube defects, Santa Cruz Biotechnology LLGL2 antibody (Santa Cruz, sc-376857) was used in immunohistochemistry - frozen section on mouse samples at 1:400 (fig 1d). Hum Mol Genet (2017) ncbi
Articles Reviewed
  1. Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed publisher
  2. Kharfallah F, Guyot M, El Hassan A, Allache R, Merello E, De Marco P, et al. Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization. Hum Mol Genet. 2017;26:2307-2320 pubmed publisher
  3. Dong W, Zhang X, Liu W, Chen Y, Huang J, Austin E, et al. A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia. J Cell Biol. 2015;211:273-86 pubmed publisher