This is a Validated Antibody Database (VAD) review about human LLGL1, based on 3 published articles (read how Labome selects the articles), using LLGL1 antibody in all methods. It is aimed to help Labome visitors find the most suited LLGL1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LLGL1 synonym: DLG4; HUGL; HUGL-1; HUGL1; LLGL; Lgl1; Mgl1

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D2B5A)
  • western blot knockout validation; mouse; loading ...; fig 3a
  • immunohistochemistry; mouse; loading ...; fig 1c
Cell Signaling Technology LLGL1 antibody (CST, 12159s) was used in western blot knockout validation on mouse samples (fig 3a) and in immunohistochemistry on mouse samples (fig 1c). Front Pharmacol (2022) ncbi
Abnova
mouse monoclonal (5G2)
  • western blot; human; loading ...; fig 3b
In order to investigate the role of CRB3 downregulation in maintaining breast cancer stem cells, Abnova LLGL1 antibody (Abnova, H00003996-M01) was used in western blot on human samples (fig 3b). Oncogenesis (2017) ncbi
mouse monoclonal (5G2)
  • western blot; human; loading ...; fig 1a
In order to propose that loss of Llgl1 results in epidermal growth factor receptor mislocalization and leads to pre-neoplastic changes, Abnova LLGL1 antibody (Abnova, H00003996-M01) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2B5A)
  • western blot knockout validation; mouse; loading ...; fig 3a
  • immunohistochemistry; mouse; loading ...; fig 1c
Cell Signaling Technology LLGL1 antibody (CST, 12159s) was used in western blot knockout validation on mouse samples (fig 3a) and in immunohistochemistry on mouse samples (fig 1c). Front Pharmacol (2022) ncbi
Articles Reviewed
  1. Zhang Y, Yuan P, Ma X, Deng Q, Gao J, Yang J, et al. Deletion of Smooth Muscle Lethal Giant Larvae 1 Promotes Neointimal Hyperplasia in Mice. Front Pharmacol. 2022;13:834296 pubmed publisher
  2. Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed publisher
  3. Greenwood E, Maisel S, Ebertz D, Russ A, Pandey R, SCHROEDER J. Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration. Oncotarget. 2016;7:60776-60792 pubmed publisher