This is a Validated Antibody Database (VAD) review about human LIN28B, based on 12 published articles (read how Labome selects the articles), using LIN28B antibody in all methods. It is aimed to help Labome visitors find the most suited LIN28B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LIN28B synonym: CSDD2

Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig ev3d
Cell Signaling Technology LIN28B antibody (Cell Signaling, 4196) was used in western blot on human samples (fig ev3d). EMBO J (2022) ncbi
domestic rabbit monoclonal (D4H1)
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology LIN28B antibody (Cell Signaling Technology, 11965) was used in western blot on human samples at 1:1000 (fig 2a). Oncogenesis (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig s1b
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology LIN28B antibody (Cell Signaling, 5422S) was used in immunohistochemistry on mouse samples (fig s1b) and in western blot on mouse samples (fig 1b). Cell Rep (2021) ncbi
domestic rabbit monoclonal (D4H1)
  • western blot; human; fig s3b
Cell Signaling Technology LIN28B antibody (CST, 11965) was used in western blot on human samples (fig s3b). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (D4H1)
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology LIN28B antibody (CST, 11965S) was used in western blot on human samples at 1:1000 (fig 5a). JCI Insight (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4i
Cell Signaling Technology LIN28B antibody (Cell Signaling, 4196) was used in western blot on human samples (fig 4i). Cancer Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology LIN28B antibody (Cell Signaling Technology, 4196S) was used in western blot on human samples (fig 1f). Cell Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4a
Cell Signaling Technology LIN28B antibody (Cell Signaling, 4196) was used in western blot on human samples (fig 4a). J Exp Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig s2c
  • western blot; human; loading ...; fig s2b
Cell Signaling Technology LIN28B antibody (Cell Signaling, 4196) was used in immunohistochemistry on human samples (fig s2c) and in western blot on human samples (fig s2b). Nature (2016) ncbi
domestic rabbit monoclonal (D4H1)
  • western blot; human; fig 2a
Cell Signaling Technology LIN28B antibody (Cell Signaling, D4H1) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology LIN28B antibody (Cell Signaling, 5422) was used in western blot on human samples (fig 6a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology LIN28B antibody (Cell Signaling, 4196) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
Articles Reviewed
  1. Paulmann C, Spallek R, Karpiuk O, Heider M, Sch xe4 ffer I, Zecha J, et al. The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma. EMBO J. 2022;41:e110871 pubmed publisher
  2. Shi J, Jin X, Wang Y, Zhu T, Zhang D, Li Q, et al. LIN28B inhibition sensitizes cells to p53-restoring PPI therapy through unleashed translational suppression. Oncogenesis. 2022;11:37 pubmed publisher
  3. Osborne J, Kinney M, Han A, Akinnola K, Yermalovich A, Vo L, et al. Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021;36:109408 pubmed publisher
  4. Szemes M, Melegh Z, Bellamy J, Park J, Chen B, Greenhough A, et al. Transcriptomic Analyses of MYCN-Regulated Genes in Anaplastic Wilms' Tumour Cell Lines Reveals Oncogenic Pathways and Potential Therapeutic Vulnerabilities. Cancers (Basel). 2021;13: pubmed publisher
  5. Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed publisher
  6. Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
  7. Wang X, Li Q, Liu C, Hall P, Jiang J, Katchis C, et al. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration. Cell Rep. 2018;24:2540-2552.e6 pubmed publisher
  8. Rowe R, Wang L, Coma S, Han A, Mathieu R, Pearson D, et al. Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis. J Exp Med. 2016;213:1497-512 pubmed publisher
  9. Powers J, Tsanov K, Pearson D, Roels F, Spina C, EBRIGHT R, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. 2016;535:246-51 pubmed publisher
  10. Hendrayani S, Al Harbi B, Al Ansari M, Silva G, Aboussekhra A. The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts. Oncotarget. 2016;7:41974-41985 pubmed publisher
  11. Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed publisher
  12. Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed publisher