This is a Validated Antibody Database (VAD) review about human LIMK2, based on 3 published articles (read how Labome selects the articles), using LIMK2 antibody in all methods. It is aimed to help Labome visitors find the most suited LIMK2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LIMK2 synonym: LIM domain kinase 2

Abcam
rabbit monoclonal (EP969Y)
  • immunohistochemistry - free floating section; rat; 1:100; fig 1
In order to facilitate LIM kinase 2-mediated programmed necrotic neuronal death by mitochondrial translocation of high mobility group box 1, Abcam LIMK2 antibody (Abcam, ab45165) was used in immunohistochemistry - free floating section on rat samples at 1:100 (fig 1). Front Cell Neurosci (2016) ncbi
rabbit monoclonal (EP969Y)
  • immunohistochemistry - frozen section; rat; 1:100; fig 4
  • western blot; rat; 1:2000; fig 4
In order to study the role of endothelin-1 in LIMK2-mediated neuronal necrosis, Abcam LIMK2 antibody (Abcam, ab45165) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 4) and in western blot on rat samples at 1:2000 (fig 4). Mol Brain (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (8C11)
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology LIMK2 antibody (Cell Signaling, 3845) was used in western blot on human samples at 1:1000 (fig s1). Oncotarget (2015) ncbi
Articles Reviewed
  1. Hyun H, Ko A, Kang T. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci. 2016;10:99 pubmed publisher
  2. Ko A, Hyun H, Min S, Kim J, Kang T. Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity. Mol Brain. 2015;8:58 pubmed publisher
  3. Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed