This is a Validated Antibody Database (VAD) review about human LIMK1, based on 20 published articles (read how Labome selects the articles), using LIMK1 antibody in all methods. It is aimed to help Labome visitors find the most suited LIMK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LIMK1 synonym: LIMK; LIMK-1; LIM domain kinase 1; LIM motif-containing protein kinase

Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig 3a
In order to assess the effects of thrombomodulin on monocyte differentiation, Abcam LIMK1 antibody (Abcam, ab38508) was used in western blot on human samples (fig 3a). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
Abcam LIMK1 antibody (Abcam, ab39641) was used in western blot on rat samples at 1:500. J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:500
Abcam LIMK1 antibody (Abcam, ab38508) was used in western blot on rat samples at 1:500. J Alzheimers Dis (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human
  • western blot; human
Abcam LIMK1 antibody (Abcam, ab39641) was used in immunohistochemistry on human samples and in western blot on human samples . Oncol Rep (2013) ncbi
OriGene
mouse monoclonal (OTI6B4)
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to elucidate the mechanism by which intronic hexanucleotide expansions in C9ORF72 contribute to amyotrophic lateral sclerosis, OriGene LIMK1 antibody (Origen, TA503012) was used in western blot on mouse samples at 1:1000 (fig 6a). Nat Neurosci (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:100; loading ...; fig 9a
Cell Signaling Technology LIMK1 antibody (Cell Signaling, RRID:AB_2281332) was used in western blot on mouse samples at 1:100 (fig 9a). elife (2019) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 9a
Cell Signaling Technology LIMK1 antibody (Cell Signaling, RRID:AB_2136943) was used in western blot on mouse samples at 1:500 (fig 9a). elife (2019) ncbi
rabbit polyclonal
  • proximity ligation assay; rat; 1:100; loading ...; fig 6d
  • western blot; rat; 1:1000; loading ...; fig 6a
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in proximity ligation assay on rat samples at 1:100 (fig 6d) and in western blot on rat samples at 1:1000 (fig 6a). EMBO J (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6a
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in western blot on mouse samples at 1:1000 (fig 6a). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6c
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on mouse samples at 1:1000 (fig 6c). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to elucidate the mechanism by which intronic hexanucleotide expansions in C9ORF72 contribute to amyotrophic lateral sclerosis, Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on mouse samples at 1:1000 (fig 6a). Nat Neurosci (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; fig 3
In order to investigate the temporally associated cessation of growth in the developing hippocampus by cofilin activation, Cell Signaling Technology LIMK1 antibody (Cell signaling, 3842) was used in western blot on rat samples at 1:1000 (fig 3). Cereb Cortex (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on mouse samples at 1:1000 (fig 6e). J Neurochem (2015) ncbi
rabbit polyclonal
  • other; mouse; 1:1000; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in other on mouse samples at 1:1000 (fig s1). Front Microbiol (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
In order to study the temporal and spatial relationship between dendritic protein synthesis and actin cytoskeleton reorganization, Cell Signaling Technology LIMK1 antibody (Cell Signaling Technology, #3842) was used in western blot on rat samples at 1:1000. J Neurosci (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig s1
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on human samples at 1:500 (fig s1). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; fig s1
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in western blot on human samples at 1:2000 (fig s1). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
In order to study how acute environmental hypoxia regulates blood glucose and downstream intramuscular insulin signaling after humans eat a meal, Cell Signaling Technology LIMK1 antibody (Cell signaling, 3842) was used in western blot on human samples (fig 5). Eur J Appl Physiol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 5
In order to study how acute environmental hypoxia regulates blood glucose and downstream intramuscular insulin signaling after humans eat a meal, Cell Signaling Technology LIMK1 antibody (Cell signaling, 3841) was used in western blot on human samples (fig 5). Eur J Appl Physiol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on human samples at 1:1000. Br J Cancer (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in western blot on human samples at 1:1000. Br J Cancer (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human; fig 1
  • western blot; human; fig 3
Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3842) was used in immunohistochemistry on human samples (fig 1) and in western blot on human samples (fig 3). Mol Cancer Ther (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
In order to investigate the role of ROCK1 and ROCK2 in cell detachment, Cell Signaling Technology LIMK1 antibody (Cell Signaling, 3841) was used in western blot on mouse samples (fig 3). Cell Death Dis (2013) ncbi
BD Biosciences
mouse monoclonal (42/LIMK1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences LIMK1 antibody (BD, 42) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (42/LIMK1)
  • immunocytochemistry; rat; 1:500
BD Biosciences LIMK1 antibody (BD Biosciences, 611748) was used in immunocytochemistry on rat samples at 1:500. J Neurosci (2015) ncbi
EMD Millipore
rat monoclonal (40/00-1B11-1-1)
  • immunohistochemistry - free floating section; mouse
  • immunocytochemistry; mouse
In order to examine the role of 14-3-3 proteins during brain development, EMD Millipore LIMK1 antibody (Millipore, MAB10750) was used in immunohistochemistry - free floating section on mouse samples and in immunocytochemistry on mouse samples . J Neurosci (2014) ncbi
Articles Reviewed
  1. Vaswani A, Weykopf B, Hagemann C, Fried H, Brüstle O, Blaess S. Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons. elife. 2019;8: pubmed publisher
  2. Rajgor D, Sanderson T, Amici M, Collingridge G, Hanley J. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018;37: pubmed publisher
  3. Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed publisher
  4. Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed publisher
  5. Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, et al. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016;19:1610-1618 pubmed publisher
  6. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  7. Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher
  8. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  9. Civiero L, Cirnaru M, Beilina A, Rodella U, Russo I, Belluzzi E, et al. Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. J Neurochem. 2015;135:1242-56 pubmed publisher
  10. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  11. Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
  12. Göttle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, et al. Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci. 2015;35:906-19 pubmed publisher
  13. Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed
  14. D Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
  15. Shi L, Zhang B, Sun X, Lu S, Liu Z, Liu Y, et al. MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1. Br J Cancer. 2014;111:2316-27 pubmed publisher
  16. Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher
  17. Toyo oka K, Wachi T, Hunt R, Baraban S, Taya S, Ramshaw H, et al. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014;34:12168-81 pubmed publisher
  18. Sun L, Guo C, Wang T, Li X, Li G, Luo Y, et al. LIMK1 is involved in the protective effects of bone morphogenetic protein 6 against amyloid-?-induced neurotoxicity in rat hippocampal neurons. J Alzheimers Dis. 2014;42:543-54 pubmed publisher
  19. Shi J, Wu X, Surma M, Vemula S, Zhang L, Yang Y, et al. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death Dis. 2013;4:e483 pubmed publisher
  20. Zhou Y, Su J, Shi L, Liao Q, Su Q. DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion. Oncol Rep. 2013;29:605-12 pubmed publisher