This is a Validated Antibody Database (VAD) review about human LETM1, based on 6 published articles (read how Labome selects the articles), using LETM1 antibody in all methods. It is aimed to help Labome visitors find the most suited LETM1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LETM1 synonym: SLC55A1; mitochondrial proton/calcium exchanger protein; LETM1 and EF-hand domain-containing protein 1, mitochondrial; Mdm38 homolog; leucine zipper-EF-hand containing transmembrane protein 1

Abnova
mouse monoclonal (6F7)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c, 1d, 1f
  • immunocytochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 4a, s2a
Abnova LETM1 antibody (Abnova, H00003954-M03) was used in immunohistochemistry - paraffin section on human samples (fig 1c, 1d, 1f), in immunocytochemistry on human samples (fig 3b) and in western blot on human samples (fig 4a, s2a). BMC Cancer (2019) ncbi
mouse monoclonal (6F7)
  • immunohistochemistry - paraffin section; human; 1:50
Abnova LETM1 antibody (Abnova, H00003954-M03) was used in immunohistochemistry - paraffin section on human samples at 1:50. Biomed Res Int (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-3)
  • western blot; human; 1:2000; loading ...; fig 1b
In order to determine the role of calcium regulation in sporadic inclusion body myositis, Santa Cruz Biotechnology LETM1 antibody (Santa Cruz, sc-271234) was used in western blot on human samples at 1:2000 (fig 1b). Acta Neuropathol Commun (2017) ncbi
mouse monoclonal (D-3)
  • immunohistochemistry - paraffin section; human; loading ...; fig 4h
  • immunocytochemistry; human; 1:100; loading ...; fig 4c
Santa Cruz Biotechnology LETM1 antibody (Santa Cruz Biotechnology, sc-271234) was used in immunohistochemistry - paraffin section on human samples (fig 4h) and in immunocytochemistry on human samples at 1:100 (fig 4c). Oncotarget (2016) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
Proteintech Group LETM1 antibody (Proteintech, 16024-1-AP) was used in western blot on mouse samples at 1:1000 (fig 1b). Nature (2017) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
MilliporeSigma LETM1 antibody (Sigma, HPA-011029) was used in western blot on human samples (fig 4d). Oncotarget (2016) ncbi
rabbit polyclonal
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, MilliporeSigma LETM1 antibody (Atlas, HPA011029) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Articles Reviewed
  1. Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019;19:898 pubmed publisher
  2. Luongo T, Lambert J, Gross P, Nwokedi M, Lombardi A, Shanmughapriya S, et al. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017;545:93-97 pubmed publisher
  3. Amici D, Pinal Fernández I, Mázala D, Lloyd T, Corse A, Christopher Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5:24 pubmed publisher
  4. Lee J, Lee W, Seol M, Lee S, Kim D, Kim H, et al. Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation. Oncotarget. 2016;7:66728-66739 pubmed publisher
  5. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  6. Chen L, Yang Y, Liu S, Piao L, Zhang Y, Lin Z, et al. High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma. Biomed Res Int. 2014;2014:850316 pubmed publisher