This is a Validated Antibody Database (VAD) review about human LCX, based on 7 published articles (read how Labome selects the articles), using LCX antibody in all methods. It is aimed to help Labome visitors find the most suited LCX antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LCX synonym: CXXC6; LCX; bA119F7.1; methylcytosine dioxygenase TET1; CXXC finger 6; CXXC zinc finger 6; CXXC-type zinc finger protein 6; TET1 splice variant VP_DE4; TET1 splice variant VP_DE456; leukemia-associated protein with a CXXC domain; ten-eleven translocation 1 gene protein; ten-eleven translocation-1; tet oncogene 1

GeneTex
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
GeneTex LCX antibody (GeneTex, GTX124207) was used in western blot on mouse samples (fig 4b). Cell Rep (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3g
GeneTex LCX antibody (Genetex, GTX124207) was used in western blot on mouse samples (fig 3g). Nucleic Acids Res (2018) ncbi
mouse monoclonal (GT1462)
  • immunohistochemistry - paraffin section; pig; 1:200; loading ...; fig s3d
In order to elucidate the inital stage of developmental events from human primordial germ cells, GeneTex LCX antibody (GeneTex, GTX627420) was used in immunohistochemistry - paraffin section on pig samples at 1:200 (fig s3d). Nature (2017) ncbi
rabbit polyclonal
  • western blot; baker's yeast; 1:10,000; fig 1
GeneTex LCX antibody (Genetex, GTX124207) was used in western blot on baker's yeast samples at 1:10,000 (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (GT1462)
  • immunocytochemistry; human; 1:250; fig 3ef
In order to identify SOX17 as a key regulator of human primordial germ cell fate, GeneTex LCX antibody (Genetex, GT1462) was used in immunocytochemistry on human samples at 1:250 (fig 3ef). Cell (2015) ncbi
OriGene
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4
OriGene LCX antibody (Origene, TA309902) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4). Biochem Biophys Res Commun (2016) ncbi
ProSci
rabbit polyclonal
  • western blot; human; 1:1000; fig 1d
ProSci LCX antibody (ProSci, 7733) was used in western blot on human samples at 1:1000 (fig 1d). J Biol Chem (2016) ncbi
Articles Reviewed
  1. Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Rep. 2018;25:3194-3203.e4 pubmed publisher
  2. Zhu F, Zhu Q, Ye D, Zhang Q, Yang Y, Guo X, et al. Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency. Nucleic Acids Res. 2018;46:6026-6040 pubmed publisher
  3. Kobayashi T, Zhang H, Tang W, Irie N, Withey S, Klisch D, et al. Principles of early human development and germ cell program from conserved model systems. Nature. 2017;546:416-420 pubmed publisher
  4. Weber A, Krawczyk C, Robertson A, Kuśnierczyk A, Vågbø C, Schuermann D, et al. Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism. Nat Commun. 2016;7:10806 pubmed publisher
  5. McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed publisher
  6. Kim H, Jang W, Kang M, Jeong J, Choi M, Sung Y, et al. TET1 contributes to neurogenesis onset time during fetal brain development in mice. Biochem Biophys Res Commun. 2016;471:437-43 pubmed publisher
  7. Irie N, Weinberger L, Tang W, Kobayashi T, Viukov S, Manor Y, et al. SOX17 is a critical specifier of human primordial germ cell fate. Cell. 2015;160:253-68 pubmed publisher