This is a Validated Antibody Database (VAD) review about human LBR, based on 4 published articles (read how Labome selects the articles), using LBR antibody in all methods. It is aimed to help Labome visitors find the most suited LBR antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LBR synonym: DHCR14B; LMN2R; PHA; TDRD18; lamin-B receptor; integral nuclear envelope inner membrane protein; tudor domain containing 18

Abcam
rabbit monoclonal (E398L)
  • immunocytochemistry; human; 1:200; loading ...; fig s3b
In order to study the role of Repo-Man in interphase, Abcam LBR antibody (Abcam, ab32535) was used in immunocytochemistry on human samples at 1:200 (fig s3b). Nat Commun (2017) ncbi
rabbit monoclonal (E398L)
  • western blot; human; loading ...; fig 1c
In order to report the interactome of all dipeptide repeat proteins, Abcam LBR antibody (Abcam, ab32535) was used in western blot on human samples (fig 1c). Cell (2016) ncbi
rabbit monoclonal (E398L)
  • western blot; human
Abcam LBR antibody (Abcam, ab32535) was used in western blot on human samples . J Biol Chem (2014) ncbi
Invitrogen
rabbit polyclonal
  • immunocytochemistry; human; 1:1000; fig 5
In order to test if a disruption in the structure of the nucleus contributes to the development of lupus autoimmunity, Invitrogen LBR antibody (ThermoFisher Scientific, PA5-42709) was used in immunocytochemistry on human samples at 1:1000 (fig 5). Dis Model Mech (2016) ncbi
Articles Reviewed
  1. de Castro I, Budzak J, Di Giacinto M, Ligammari L, Gokhan E, Spanos C, et al. Repo-Man/PP1 regulates heterochromatin formation in interphase. Nat Commun. 2017;8:14048 pubmed publisher
  2. Lee K, Zhang P, Kim H, Mitrea D, Sarkar M, Freibaum B, et al. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell. 2016;167:774-788.e17 pubmed publisher
  3. Singh N, Johnstone D, Martin K, Tempera I, Kaplan M, Denny M. Alterations in nuclear structure promote lupus autoimmunity in a mouse model. Dis Model Mech. 2016;9:885-97 pubmed publisher
  4. Wang Y, Yang Y, Wu S, Pan S, Zhou C, Ma Y, et al. p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress. J Biol Chem. 2014;289:35795-805 pubmed publisher