This is a Validated Antibody Database (VAD) review about human KPNB1, based on 14 published articles (read how Labome selects the articles), using KPNB1 antibody in all methods. It is aimed to help Labome visitors find the most suited KPNB1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KPNB1 synonym: IMB1; IPO1; IPOB; Impnb; NTF97; importin subunit beta-1; PTAC97; importin 1; importin 90; importin beta-1 subunit; karyopherin (importin) beta 1; nuclear factor p97; pore targeting complex 97 kDa subunit

Abcam
mouse monoclonal (3E9)
  • immunoprecipitation; human; loading ...; fig 3
  • western blot; human; 1:500; loading ...; fig 3
In order to discover karyopherin alpha 7 cargo proteins, Abcam KPNB1 antibody (Abcam, ab2811) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples at 1:500 (fig 3). Biochim Biophys Acta Mol Basis Dis (2017) ncbi
mouse monoclonal (3E9)
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; 1:3000; loading ...; fig 4a
Abcam KPNB1 antibody (Abcam, ab2811) was used in immunocytochemistry on human samples (fig 4b) and in western blot on human samples at 1:3000 (fig 4a). J Cell Sci (2016) ncbi
mouse monoclonal (3E9)
  • western blot; human; fig 1
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Abcam KPNB1 antibody (Abcam, ab2811) was used in western blot on human samples (fig 1). J Cell Biol (2016) ncbi
mouse monoclonal (3E9)
  • immunocytochemistry; human; 1:10,000; fig 7
  • western blot; human; 1:2000; fig 7
Abcam KPNB1 antibody (Abcam, ab2811) was used in immunocytochemistry on human samples at 1:10,000 (fig 7) and in western blot on human samples at 1:2000 (fig 7). Nat Commun (2015) ncbi
mouse monoclonal (3E9)
  • immunocytochemistry; human; fig 2
  • immunoprecipitation; mouse; fig 2
Abcam KPNB1 antibody (Abcam, ab2811) was used in immunocytochemistry on human samples (fig 2) and in immunoprecipitation on mouse samples (fig 2). elife (2015) ncbi
mouse monoclonal (3E9)
  • western blot; Leishmania; loading ...; fig 4d
Abcam KPNB1 antibody (Abcam, ab2811) was used in western blot on Leishmania samples (fig 4d). PLoS Pathog (2015) ncbi
mouse monoclonal (3E9)
  • immunocytochemistry; human
  • western blot; human
In order to study the role of nucleoporin RanBP2/Nup358 in chromosomal alignment and mitotic integrity, Abcam KPNB1 antibody (Abcam, ab2811) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Death Dis (2013) ncbi
mouse monoclonal (3E9)
  • western blot; mouse; 1:1,000
Abcam KPNB1 antibody (Abcam, ab2811) was used in western blot on mouse samples at 1:1,000. In Vitro Cell Dev Biol Anim (2013) ncbi
mouse monoclonal (3E9)
  • western blot; human
Abcam KPNB1 antibody (Abcam, ab2811) was used in western blot on human samples . PLoS ONE (2012) ncbi
rabbit polyclonal
  • western blot; human
Abcam KPNB1 antibody (Abcam, ab45938) was used in western blot on human samples . Pulm Circ (2012) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; fig 6
Bethyl KPNB1 antibody (bethyl, A300-482A) was used in western blot on human samples (fig 6). RNA (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Bethyl KPNB1 antibody (Bethyl Labratories, A300-482A) was used in western blot on human samples (fig 1). elife (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-7)
  • western blot; human; fig 1
Santa Cruz Biotechnology KPNB1 antibody (Santa Cruz, sc-137016) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
mouse monoclonal (H-7)
  • western blot; human; fig 3a
Santa Cruz Biotechnology KPNB1 antibody (Santa, sc-137016) was used in western blot on human samples (fig 3a). Oncotarget (2014) ncbi
mouse monoclonal (H-7)
  • immunoprecipitation; human
  • western blot; human
In order to study the role of nucleoporin RanBP2/Nup358 in chromosomal alignment and mitotic integrity, Santa Cruz Biotechnology KPNB1 antibody (Santa Cruz Biotechnology, sc-137016) was used in immunoprecipitation on human samples and in western blot on human samples . Cell Death Dis (2013) ncbi
GeneTex
mouse monoclonal (3E9)
  • western blot; human
GeneTex KPNB1 antibody (GeneTex, GTX 22811) was used in western blot on human samples . J Biomed Sci (2015) ncbi
Articles Reviewed
  1. Vuorinen E, Rajala N, Rauhala H, Nurminen A, Hytönen V, Kallioniemi A. Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth. Biochim Biophys Acta Mol Basis Dis. 2017;1863:211-219 pubmed publisher
  2. Madugula V, Lu L. A ternary complex comprising transportin1, Rab8 and the ciliary targeting signal directs proteins to ciliary membranes. J Cell Sci. 2016;129:3922-3934 pubmed
  3. Kalantari R, Hicks J, Li L, Gagnon K, Sridhara V, Lemoff A, et al. Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells. RNA. 2016;22:1085-98 pubmed publisher
  4. Pecháčková S, Burdova K, Benada J, Kleiblova P, Jenikova G, Macurek L. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. Oncotarget. 2016;7:14458-75 pubmed publisher
  5. Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed publisher
  6. Qian J, Beullens M, Huang J, De Munter S, Lesage B, Bollen M. Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch. Nat Commun. 2015;6:10215 pubmed publisher
  7. Lee Y, Jang A, Francey L, Sehgal A, Hogenesch J. KPNB1 mediates PER/CRY nuclear translocation and circadian clock function. elife. 2015;4: pubmed publisher
  8. Yang C, Chiang C, Chen C, Lee Y, Wu M, Tsou Y, et al. Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci. 2015;22:33 pubmed publisher
  9. Isnard A, Christian J, Kodiha M, Stochaj U, McMaster W, Olivier M. Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity. PLoS Pathog. 2015;11:e1004776 pubmed publisher
  10. Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
  11. Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
  12. You P, Peng Z, Wang Y, Tao T. Expression and subcellular distribution of imp13 are regulated in brain development. In Vitro Cell Dev Biol Anim. 2013;49:346-53 pubmed publisher
  13. Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed publisher
  14. Talati M, Seeley E, Ihida Stansbury K, Delisser H, McDonald H, Ye F, et al. Altered expression of nuclear and cytoplasmic histone H1 in pulmonary artery and pulmonary artery smooth muscle cells in patients with IPAH. Pulm Circ. 2012;2:340-51 pubmed publisher