This is a Validated Antibody Database (VAD) review about human KPNA1, based on 8 published articles (read how Labome selects the articles), using KPNA1 antibody in all methods. It is aimed to help Labome visitors find the most suited KPNA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KPNA1 synonym: IPOA5; NPI-1; RCH2; SRP1

Knockout validation
MBL International
rat monoclonal (2D9)
  • western blot knockout validation; mouse; 1:500; fig 1
MBL International KPNA1 antibody (MBL, D170-3) was used in western blot knockout validation on mouse samples at 1:500 (fig 1). FEBS J (2011) ncbi
Santa Cruz Biotechnology
mouse monoclonal (187.1)
  • western blot; mouse; 1:200; loading ...; fig 4a
In order to elucidate how nuclear editing of substrates contributes to neuronal function and brain development, Santa Cruz Biotechnology KPNA1 antibody (Santa Cruz, 187.1) was used in western blot on mouse samples at 1:200 (fig 4a). J Cell Sci (2017) ncbi
mouse monoclonal (187.1)
  • western blot; human; 1:1000; fig 2
Santa Cruz Biotechnology KPNA1 antibody (Santa Cruz, sc-101292) was used in western blot on human samples at 1:1000 (fig 2). PLoS Pathog (2016) ncbi
Proteintech Group
domestic rabbit polyclonal
  • immunoprecipitation; rat; loading ...; fig 2a
  • western blot; rat; loading ...; fig 2f
Proteintech Group KPNA1 antibody (Proteintech, 18137-1-AP) was used in immunoprecipitation on rat samples (fig 2a) and in western blot on rat samples (fig 2f). Cell Commun Signal (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Proteintech Group KPNA1 antibody (ProteinTech, 18137-1-AP) was used in western blot on human samples (fig 2a). elife (2018) ncbi
Abnova
mouse monoclonal (2A4-1B5)
  • western blot; human
Abnova KPNA1 antibody (Abnova, H00003836-M01) was used in western blot on human samples . Biochem Biophys Res Commun (2015) ncbi
Invitrogen
mouse monoclonal (114-E12)
  • western blot; human; 1:250; fig 3
In order to study nuclear localization and assembly of ORC(1-6) complexes, Invitrogen KPNA1 antibody (Invitrogen, 37-0800) was used in western blot on human samples at 1:250 (fig 3). J Biol Chem (2011) ncbi
GeneTex
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2e
In order to study the promotion of lysosomal biogenesis and autophagy by nucleus-translocated ACSS2, GeneTex KPNA1 antibody (Genetex, GTX112284) was used in western blot on human samples (fig 2e). Mol Cell (2017) ncbi
MBL International
rat monoclonal (2D9)
  • western blot knockout validation; mouse; 1:500; fig 1
MBL International KPNA1 antibody (MBL, D170-3) was used in western blot knockout validation on mouse samples at 1:500 (fig 1). FEBS J (2011) ncbi
Articles Reviewed
  1. Ayanlaja A, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, et al. Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression. Cell Commun Signal. 2020;18:24 pubmed publisher
  2. Kane M, Rebensburg S, Takata M, Zang T, Yamashita M, Kvaratskhelia M, et al. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2. elife. 2018;7: pubmed publisher
  3. Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher
  4. Behm M, Wahlstedt H, Widmark A, Eriksson M, Ohman M. Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development. J Cell Sci. 2017;130:745-753 pubmed publisher
  5. Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, et al. Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. PLoS Pathog. 2016;12:e1005764 pubmed publisher
  6. Moriyama T, Sangel P, Yamaguchi H, Obuse C, Miyamoto Y, Oka M, et al. Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box. Biochem Biophys Res Commun. 2015;462:201-7 pubmed publisher
  7. Ghosh S, Vassilev A, Zhang J, Zhao Y, DePamphilis M. Assembly of the human origin recognition complex occurs through independent nuclear localization of its components. J Biol Chem. 2011;286:23831-41 pubmed publisher
  8. Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, Yoneda Y. Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery. FEBS J. 2011;278:1561-72 pubmed publisher