This is a Validated Antibody Database (VAD) review about human KMT2B, based on 4 published articles (read how Labome selects the articles), using KMT2B antibody in all methods. It is aimed to help Labome visitors find the most suited KMT2B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KMT2B synonym: CXXC10; DYT28; HRX2; MLL1B; MLL2; MLL4; TRX2; WBP-7; WBP7

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D6X2E)
  • western blot knockout validation; human; loading ...; fig s8a
Cell Signaling Technology KMT2B antibody (Cell signaling, D6X2E) was used in western blot knockout validation on human samples (fig s8a). Science (2020) ncbi
Abcam
domestic goat polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 5e
  • chromatin immunoprecipitation; human; loading ...; fig 5c
Abcam KMT2B antibody (abcam, ab104444) was used in immunohistochemistry - paraffin section on human samples (fig 5e) and in chromatin immunoprecipitation on human samples (fig 5c). PLoS ONE (2016) ncbi
domestic goat polyclonal
  • western blot; mouse; 1:500; fig 2
Abcam KMT2B antibody (Abcam, ab104444) was used in western blot on mouse samples at 1:500 (fig 2). Nat Commun (2016) ncbi
MilliporeSigma
mouse monoclonal (4C10)
  • immunoprecipitation; human; fig 6
MilliporeSigma KMT2B antibody (Sigma-Aldrich, WH0009757M2) was used in immunoprecipitation on human samples (fig 6). elife (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6X2E)
  • western blot knockout validation; human; loading ...; fig s8a
Cell Signaling Technology KMT2B antibody (Cell signaling, D6X2E) was used in western blot knockout validation on human samples (fig s8a). Science (2020) ncbi
Articles Reviewed
  1. Uckelmann H, Kim S, Wong E, Hatton C, Giovinazzo H, Gadrey J, et al. Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia. Science. 2020;367:586-590 pubmed publisher
  2. Su C, Lin I, Tzeng T, Hsieh W, Hsu M. Regulation of IL-20 Expression by Estradiol through KMT2B-Mediated Epigenetic Modification. PLoS ONE. 2016;11:e0166090 pubmed publisher
  3. Fulcoli F, Franzese M, Liu X, Zhang Z, Angelini C, Baldini A. Rebalancing gene haploinsufficiency in vivo by targeting chromatin. Nat Commun. 2016;7:11688 pubmed publisher
  4. Thandapani P, Song J, Gandin V, Cai Y, Rouleau S, Garant J, et al. Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. elife. 2015;4: pubmed publisher