This is a Validated Antibody Database (VAD) review about human KDM6A, based on 5 published articles (read how Labome selects the articles), using KDM6A antibody in all methods. It is aimed to help Labome visitors find the most suited KDM6A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KDM6A synonym: KABUK2; UTX; bA386N14.2

Knockout validation
Abcam
mouse monoclonal (3A2)
  • western blot knockout validation; human; 1:1000; fig s4
Abcam KDM6A antibody (Abcam, ab91231) was used in western blot knockout validation on human samples at 1:1000 (fig s4). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3Q1I)
  • western blot knockout validation; mouse; fig 3d
Cell Signaling Technology KDM6A antibody (Cell Signaling, 33510) was used in western blot knockout validation on mouse samples (fig 3d). Cancer Cell (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; mouse; 1:100; loading ...; fig 3a
Santa Cruz Biotechnology KDM6A antibody (Santa Cruz, sc-514859) was used in western blot on mouse samples at 1:100 (fig 3a). EMBO Mol Med (2019) ncbi
Abcam
mouse monoclonal (3A2)
  • western blot knockout validation; human; 1:1000; fig s4
Abcam KDM6A antibody (Abcam, ab91231) was used in western blot knockout validation on human samples at 1:1000 (fig s4). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; fig 5
  • western blot; human; fig 5
Abcam KDM6A antibody (Abcam, 36938) was used in chromatin immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 5). Stem Cell Reports (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3Q1I)
  • western blot; human; 1:1000; loading ...; fig s24d
Cell Signaling Technology KDM6A antibody (Cell Signaling Technology, 33510) was used in western blot on human samples at 1:1000 (fig s24d). Science (2019) ncbi
domestic rabbit monoclonal (D3Q1I)
  • western blot knockout validation; mouse; fig 3d
Cell Signaling Technology KDM6A antibody (Cell Signaling, 33510) was used in western blot knockout validation on mouse samples (fig 3d). Cancer Cell (2018) ncbi
Articles Reviewed
  1. Lin C, Hsu Y, Huang Y, Shih Y, Wang C, Chiang W, et al. A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction. EMBO Mol Med. 2019;11: pubmed publisher
  2. Chakraborty A, Laukka T, Myllykoski M, Ringel A, Booker M, Tolstorukov M, et al. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science. 2019;363:1217-1222 pubmed publisher
  3. Andricovich J, Perkail S, Kai Y, Casasanta N, Peng W, Tzatsos A. Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. Cancer Cell. 2018;33:512-526.e8 pubmed publisher
  4. Ahn J, Kim K, Park S, Ahn Y, Kim H, Yoon H, et al. Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer. Oncotarget. 2016;7:63252-63260 pubmed publisher
  5. Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al. Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. Stem Cell Reports. 2016;6:772-783 pubmed publisher