This is a Validated Antibody Database (VAD) review about human KCNQ2, based on 5 published articles (read how Labome selects the articles), using KCNQ2 antibody in all methods. It is aimed to help Labome visitors find the most suited KCNQ2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KCNQ2 synonym: BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2; potassium voltage-gated channel subfamily KQT member 2; neuroblastoma-specific potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; voltage-gated potassium channel subunit Kv7.2

Invitrogen
rabbit polyclonal
  • western blot; human; 1:200; loading ...; fig 2d
  • immunoprecipitation; rat; loading ...; fig 8
  • immunocytochemistry; rat; 1:200; loading ...; fig 1b
In order to demonstrate that fibroblast growth factor 14 affects KCNQ channel function and localization, Invitrogen KCNQ2 antibody (ThermoFisher Scientific, PA1-929) was used in western blot on human samples at 1:200 (fig 2d), in immunoprecipitation on rat samples (fig 8) and in immunocytochemistry on rat samples at 1:200 (fig 1b). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; rat; 1:50
Invitrogen KCNQ2 antibody (Pierce, PA1-929) was used in immunohistochemistry - free floating section on rat samples at 1:50. Acta Physiol (Oxf) (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 3e
In order to study the function of the giant exon of ankyrin-G, Invitrogen KCNQ2 antibody (Thermo Fisher, PA1-929) was used in immunohistochemistry - paraffin section on mouse samples (fig 3e). Proc Natl Acad Sci U S A (2015) ncbi
Neuromab
mouse monoclonal (N26A/23)
  • immunohistochemistry - free floating section; rat; 1:50
Neuromab KCNQ2 antibody (NeuroMab, 75-079) was used in immunohistochemistry - free floating section on rat samples at 1:50. Acta Physiol (Oxf) (2015) ncbi
mouse monoclonal (N26A/23)
  • immunoprecipitation; rat
  • western blot; rat; 1:200
In order to identify the molecular mechanisms that regulate the enrichment of KCNQ channels at the neuronal axon, Neuromab KCNQ2 antibody (Neuromab, N26A/23) was used in immunoprecipitation on rat samples and in western blot on rat samples at 1:200. PLoS ONE (2014) ncbi
mouse monoclonal (N26A/23)
  • immunohistochemistry - frozen section; rat
Neuromab KCNQ2 antibody (NeuroMab, N26A/23) was used in immunohistochemistry - frozen section on rat samples . J Comp Neurol (2008) ncbi
Articles Reviewed
  1. Pablo J, Pitt G. FGF14 is a regulator of KCNQ2/3 channels. Proc Natl Acad Sci U S A. 2017;114:154-159 pubmed publisher
  2. Salomonsson M, Brasen J, Braunstein T, Hagelqvist P, Holstein Rathlou N, Sorensen C. K(V)7.4 channels participate in the control of rodent renal vascular resting tone. Acta Physiol (Oxf). 2015;214:402-14 pubmed publisher
  3. Jenkins P, Kim N, Jones S, Tseng W, Svitkina T, Yin H, et al. Giant ankyrin-G: a critical innovation in vertebrate evolution of fast and integrated neuronal signaling. Proc Natl Acad Sci U S A. 2015;112:957-64 pubmed publisher
  4. Cavaretta J, Sherer K, Lee K, Kim E, Issema R, Chung H. Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit. PLoS ONE. 2014;9:e103655 pubmed publisher
  5. Buniel M, Glazebrook P, Ramirez Navarro A, Kunze D. Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body. J Comp Neurol. 2008;510:367-77 pubmed publisher