This is a Validated Antibody Database (VAD) review about human KCNN4, based on 7 published articles (read how Labome selects the articles), using KCNN4 antibody in all methods. It is aimed to help Labome visitors find the most suited KCNN4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KCNN4 synonym: DHS2; IK; IK1; IKCA1; KCA4; KCa3.1; SK4; hIKCa1; hKCa4; hSK4

Santa Cruz Biotechnology
mouse monoclonal (D-5)
  • western blot; mouse; 1:100; loading ...; fig 1a
Santa Cruz Biotechnology KCNN4 antibody (Santa Cruz, sc-365265) was used in western blot on mouse samples at 1:100 (fig 1a). elife (2020) ncbi
mouse monoclonal (D-5)
  • immunocytochemistry; rat; 1:250; loading ...; fig 2a
Santa Cruz Biotechnology KCNN4 antibody (Santa, sc-365265) was used in immunocytochemistry on rat samples at 1:250 (fig 2a). Cell Rep (2019) ncbi
mouse monoclonal (D-5)
  • immunohistochemistry; human; fig s3a
Santa Cruz Biotechnology KCNN4 antibody (Santa Cruz, sc-365265) was used in immunohistochemistry on human samples (fig s3a). Front Endocrinol (Lausanne) (2017) ncbi
Alomone Labs
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig s2e
Alomone Labs KCNN4 antibody (Alomone, APC-064) was used in western blot on human samples at 1:500 (fig s2e). Int J Mol Sci (2021) ncbi
mouse monoclonal (6C1.)
  • immunocytochemistry; human; loading ...; fig 3a
Alomone Labs KCNN4 antibody (Alomone labs, 6C1) was used in immunocytochemistry on human samples (fig 3a). Front Pharmacol (2020) ncbi
mouse monoclonal (6C1.)
  • immunocytochemistry; mouse; 1:100; fig 3
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Alomone Labs KCNN4 antibody (Alomone, ALM-051) was used in immunocytochemistry on mouse samples at 1:100 (fig 3). PLoS ONE (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig 3c
In order to measure mRNA expression and functional changes altered in response to edema and increased intracranial pressure in human neurons, Invitrogen KCNN4 antibody (Thermo, PA5-33875) was used in immunohistochemistry on human samples at 1:100 (fig 3c). Acta Neuropathol Commun (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
  • western blot; mouse; 1:1000; fig 1
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Invitrogen KCNN4 antibody (Thermo Fisher Scientific, PA5-33875) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5) and in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
Articles Reviewed
  1. Centeio R, Ousingsawat J, Schreiber R, Kunzelmann K. CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A. Int J Mol Sci. 2021;22: pubmed publisher
  2. MacKay C, Leo M, Fernández Peña C, Hasan R, Yin W, Mata Daboin A, et al. Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure. elife. 2020;9: pubmed publisher
  3. Chimote A, Gawali V, Newton H, Wise Draper T, Conforti L. A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8+ T Cells in Head and Neck Cancer. Front Pharmacol. 2020;11:143 pubmed publisher
  4. Sahu G, Wazen R, Colarusso P, Chen S, Zamponi G, Turner R. Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability. Cell Rep. 2019;28:2427-2442.e6 pubmed publisher
  5. Lin B, Lin X, Stachel M, Wang E, Luo Y, Lader J, et al. Culture in Glucose-Depleted Medium Supplemented with Fatty Acid and 3,3',5-Triiodo-l-Thyronine Facilitates Purification and Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Front Endocrinol (Lausanne). 2017;8:253 pubmed publisher
  6. Faragó N, Kocsis Ã, Braskó C, Lovas S, Rózsa M, Baka J, et al. Human neuronal changes in brain edema and increased intracranial pressure. Acta Neuropathol Commun. 2016;4:78 pubmed publisher
  7. Li Y, Hu H, Butterworth M, Tian J, Zhu M, O Neil R. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. PLoS ONE. 2016;11:e0155006 pubmed publisher