This is a Validated Antibody Database (VAD) review about human KARS1, based on 25 published articles (read how Labome selects the articles), using KARS1 antibody in all methods. It is aimed to help Labome visitors find the most suited KARS1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
KARS1 synonym: CMTRIB; DFNB89; KARS; KARS2; KRS

Abcam
domestic rabbit monoclonal (EPR7921)
  • western blot; human; loading ...; fig 3
Abcam KARS1 antibody (Abcam, ab129080) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (EPR7921)
  • western blot; human
Abcam KARS1 antibody (Abcam, ab129080) was used in western blot on human samples . PLoS ONE (2013) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:1000; loading ...; fig 4i
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198S) was used in western blot on human samples at 1:1000 (fig 4i). Mol Neurodegener (2022) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; loading ...; fig s30b
Cell Signaling Technology KARS1 antibody (Cell Signaling, D3Z1E) was used in western blot on mouse samples (fig s30b). Nat Commun (2022) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; 1:1000; fig 2b
Cell Signaling Technology KARS1 antibody (Cell Signaling Technologies, 13198) was used in western blot on mouse samples at 1:1000 (fig 2b). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2b
Cell Signaling Technology KARS1 antibody (Cell Signaling Technologies, 2715) was used in western blot on mouse samples at 1:1000 (fig 2b). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:1000; loading ...; fig 7j
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on human samples at 1:1000 (fig 7j). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198S) was used in western blot on human samples (fig 2d). J Immunol (2019) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:2000; loading ...; fig 3a
  • western blot; mouse; 1:2000; loading ...; fig 3c
Cell Signaling Technology KARS1 antibody (Cell signaling, 13198) was used in western blot on human samples at 1:2000 (fig 3a) and in western blot on mouse samples at 1:2000 (fig 3c). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; 1:1000; loading ...; fig 6c
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on mouse samples at 1:1000 (fig 6c). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:300; loading ...; fig 7i
Cell Signaling Technology KARS1 antibody (Cell Signaling, D3Z1E) was used in western blot on human samples at 1:300 (fig 7i). Cell Mol Gastroenterol Hepatol (2018) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology KARS1 antibody (Cell Signaling Technology, 13198) was used in western blot on mouse samples (fig 3f). Neuron (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3a
Cell Signaling Technology KARS1 antibody (Cell Signaling, 2715) was used in western blot on human samples at 1:1000 (fig 3a). Mol Med Rep (2018) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:1000; fig 3a
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13,198) was used in western blot on human samples at 1:1000 (fig 3a). Mol Med Rep (2018) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; loading ...; fig 2c
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on mouse samples (fig 2c). Bone (2018) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on mouse samples (fig 6a). Mol Biol Cell (2017) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on human samples (fig 3c). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3a
In order to show that QS-21 directly activated human monocyte-derived dendritic cells and promoted a pro-inflammatory transcriptional program, Cell Signaling Technology KARS1 antibody (Cell Signaling, 2715) was used in western blot on human samples at 1:1000 (fig 3a). Front Immunol (2016) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; rat; 1:1000; loading ...; fig 3b
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on rat samples at 1:1000 (fig 3b). Brain Behav Immun (2017) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; loading ...; fig 5d
In order to report that therapeutic antibody-dependent tumor cell killing was FcgammaR-dependent and mediated by macrophages, Cell Signaling Technology KARS1 antibody (Cell Signalling, 13198) was used in western blot on human samples (fig 5d). Oncogene (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology KARS1 antibody (Cell Signalling, 2715) was used in western blot on human samples at 1:1000 (fig 6). elife (2016) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; fig 5
Cell Signaling Technology KARS1 antibody (CST, D3Z1E) was used in western blot on mouse samples (fig 5). Front Pharmacol (2016) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; fig 4a
Cell Signaling Technology KARS1 antibody (Cell Signaling, D3Z1E) was used in western blot on mouse samples (fig 4a). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; fig s1
Cell Signaling Technology KARS1 antibody (Cell Signalling, 13198) was used in western blot on human samples (fig s1). Eur J Immunol (2016) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology KARS1 antibody (Cell Signaling, 13198) was used in western blot on human samples at 1:1000 (fig 4a). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D3Z1E)
  • western blot; mouse; 1:1000; fig 6e
In order to explore a macrophage TLR9-BTK-calcineurin-NFAT signaling pathway involved in impair fungal immunity, Cell Signaling Technology KARS1 antibody (Cell signaling, 13198) was used in western blot on mouse samples at 1:1000 (fig 6e). EMBO Mol Med (2015) ncbi
BD Biosciences
mouse monoclonal (4D10)
  • flow cytometry; human
BD Biosciences KARS1 antibody (BD Biosciences, 552476) was used in flow cytometry on human samples . Eur J Immunol (2014) ncbi
Articles Reviewed
  1. Zhao P, Xu Y, Jiang L, Fan X, Ku Z, Li L, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Mol Neurodegener. 2022;17:44 pubmed publisher
  2. Satofuka H, Abe S, Moriwaki T, Okada A, Kazuki K, Tanaka H, et al. Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci. Nat Commun. 2022;13:1841 pubmed publisher
  3. Lian C, Zhao L, Qiu J, Wang Y, Chen R, Liu Z, et al. miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/SYK/VEGFR-2 downregulation. Aging (Albany NY). 2020;12:22599-22613 pubmed publisher
  4. van der Wel T, Hilhorst R, den Dulk H, van den Hooven T, Prins N, Wijnakker J, et al. Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis. Nat Commun. 2020;11:3216 pubmed publisher
  5. Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher
  6. Duan S, Koziol White C, Jester W, Nycholat C, Macauley M, Panettieri R, et al. CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen. J Clin Invest. 2019;129:1387-1401 pubmed publisher
  7. Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
  8. Duggan S, Garry C, Behan F, Phipps S, Kudo H, Kirca M, et al. siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth. Cell Mol Gastroenterol Hepatol. 2018;5:569-590 pubmed publisher
  9. Zhao Y, Wu X, Li X, Jiang L, Gui X, Liu Y, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 2018;97:1023-1031.e7 pubmed publisher
  10. Park G, Kim D. Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway. Mol Med Rep. 2018;17:3563-3574 pubmed publisher
  11. Fujita S, Mukai T, Mito T, Kodama S, Nagasu A, Kittaka M, et al. Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis. Bone. 2018;106:156-166 pubmed publisher
  12. Schwartz S, Cleyrat C, Olah M, Relich P, Phillips G, Hlavacek W, et al. Differential mast cell outcomes are sensitive to FcεRI-Syk binding kinetics. Mol Biol Cell. 2017;28:3397-3414 pubmed publisher
  13. Mondello P, Derenzini E, Asgari Z, Philip J, Brea E, SESHAN V, et al. Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma. Oncotarget. 2017;8:14017-14028 pubmed publisher
  14. Welsby I, Detienne S, N kuli F, Thomas S, Wouters S, Bechtold V, et al. Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21. Front Immunol. 2016;7:663 pubmed publisher
  15. Xie Y, Guo H, Wang L, Xu L, Zhang X, Yu L, et al. Human albumin attenuates excessive innate immunity via inhibition of microglial Mincle/Syk signaling in subarachnoid hemorrhage. Brain Behav Immun. 2017;60:346-360 pubmed publisher
  16. Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo S, et al. Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene. 2017;36:2366-2376 pubmed publisher
  17. Justa Schuch D, Silva Garcia M, Pilla E, Engelke M, Kilisch M, Lenz C, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. elife. 2016;5: pubmed publisher
  18. Huang Y, Li P, Wang J, Zhou H, Yang Z, Yang R, et al. Inhibition of Sophocarpine on Poly I: C/D-GalN-Induced Immunological Liver Injury in Mice. Front Pharmacol. 2016;7:256 pubmed publisher
  19. Wittmann A, Lamprinaki D, Bowles K, Katzenellenbogen E, Knirel Y, Whitfield C, et al. Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells. J Biol Chem. 2016;291:17629-38 pubmed publisher
  20. Elder M, Webster S, Williams D, Gaston J, Goodall J. TSLP production by dendritic cells is modulated by IL-1β and components of the endoplasmic reticulum stress response. Eur J Immunol. 2016;46:455-63 pubmed publisher
  21. Park S, Ahn H, Kim J, Lee C. Evaluation of Multi-tRNA Synthetase Complex by Multiple Reaction Monitoring Mass Spectrometry Coupled with Size Exclusion Chromatography. PLoS ONE. 2015;10:e0142253 pubmed publisher
  22. Callaway J, Smith S, McKinnon K, de Silva A, Crowe J, Ting J. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015;290:17306-20 pubmed publisher
  23. Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
  24. Cohen Kedar S, Baram L, Elad H, Brazowski E, Guzner Gur H, Dotan I. Human intestinal epithelial cells respond to β-glucans via Dectin-1 and Syk. Eur J Immunol. 2014;44:3729-40 pubmed publisher
  25. Kim K, Park S, Na S, Kim J, Choi H, Kim Y, et al. Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex. PLoS ONE. 2013;8:e81734 pubmed publisher