This is a Validated Antibody Database (VAD) review about human ITPR1, based on 18 published articles (read how Labome selects the articles), using ITPR1 antibody in all methods. It is aimed to help Labome visitors find the most suited ITPR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ITPR1 synonym: ACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s5a
Cell Signaling Technology ITPR1 antibody (Cell Signaling, 3763) was used in western blot knockout validation on human samples at 1:1000 (fig s5a). Cell Rep (2018) ncbi
Abcam
domestic rabbit monoclonal (EPR4537)
  • western blot; mouse; 1:200; loading ...; fig 1h
Abcam ITPR1 antibody (Abcam, AB108517) was used in western blot on mouse samples at 1:200 (fig 1h). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s6
Abcam ITPR1 antibody (Abcam, ab5804) was used in western blot on mouse samples (fig s6). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 3a
In order to show protein disulfide isomerases bind to N-methyl-D-aspartate receptor in the normal hippocampus, and that this binding is increased in chronic epileptic rats, Abcam ITPR1 antibody (Abcam, ab5804) was used in western blot on rat samples at 1:1000 (fig 3a). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 4
Abcam ITPR1 antibody (Abcam, ab5804) was used in western blot on rat samples at 1:1000 (fig 4). Chin Med J (Engl) (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-8)
  • western blot; rat; 1:500; loading ...; fig 6b
Santa Cruz Biotechnology ITPR1 antibody (Santa, sc-271197) was used in western blot on rat samples at 1:500 (fig 6b). J Inflamm (Lond) (2020) ncbi
mouse monoclonal (B-2)
  • western blot; human; 1:200; fig 1
Santa Cruz Biotechnology ITPR1 antibody (Santa Cruz Biotechnology, sc-377518) was used in western blot on human samples at 1:200 (fig 1). Stem Cells Dev (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 5a
In order to explore the effects of bisacodyl on glioblastoma stem-like cells, Invitrogen ITPR1 antibody (Thermo scientific, PA1-901) was used in immunocytochemistry on human samples at 1:100 (fig 5a). Biochim Biophys Acta Mol Cell Res (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1a
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to discuss newly identified autoantibodies associated with cerebellar disorders, Invitrogen ITPR1 antibody (ThermoFisher Scientific, PA1-901) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1a) and in western blot on mouse samples at 1:1000 (fig 1b). Neurol Neuroimmunol Neuroinflamm (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 1
In order to discuss potential technical problems while performing vivo electrophysiological recordings, Invitrogen ITPR1 antibody (Thermo Scientific, PA1-901) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 1). J Neurosci Methods (2016) ncbi
BioLegend
mouse monoclonal (L24/18)
BioLegend ITPR1 antibody (BioLegend, 817701) was used . EMBO Mol Med (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s5a
Cell Signaling Technology ITPR1 antibody (Cell Signaling, 3763) was used in western blot knockout validation on human samples at 1:1000 (fig s5a). Cell Rep (2018) ncbi
domestic rabbit monoclonal (D53A5)
  • western blot; human; fig e1d
In order to show the role of Pex3 and Pex14 in generating human peroxisomes, Cell Signaling Technology ITPR1 antibody (Cell Signalling, 8568) was used in western blot on human samples (fig e1d). Nature (2017) ncbi
domestic rabbit monoclonal (D53A5)
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology ITPR1 antibody (cell signalling, 8568) was used in western blot on human samples (fig 3c). EMBO Mol Med (2016) ncbi
domestic rabbit monoclonal (D10E3)
  • western blot; mouse; 1:2000; fig 4
Cell Signaling Technology ITPR1 antibody (Cell Signaling, 8548) was used in western blot on mouse samples at 1:2000 (fig 4). Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (D53A5)
  • western blot; human
Cell Signaling Technology ITPR1 antibody (Cell Signaling, 8568) was used in western blot on human samples . Biomed Chromatogr (2014) ncbi
domestic rabbit monoclonal (D10E3)
  • western blot; human
Cell Signaling Technology ITPR1 antibody (Cell Signaling, 8548) was used in western blot on human samples . Biomed Chromatogr (2014) ncbi
EMD Millipore
domestic rabbit polyclonal
  • western blot; human; 1:800; loading ...; fig 4a
EMD Millipore ITPR1 antibody (EMD Millipore, 07-1213) was used in western blot on human samples at 1:800 (fig 4a). Mol Med Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 1a
EMD Millipore ITPR1 antibody (Millipore, 071210) was used in western blot on human samples at 1:1000 (fig 1a). PLoS ONE (2016) ncbi
mouse monoclonal
  • western blot; mouse; 1:400; loading ...; fig 3g
EMD Millipore ITPR1 antibody (Calbiochem, 407140) was used in western blot on mouse samples at 1:400 (fig 3g). Nat Commun (2014) ncbi
Articles Reviewed
  1. Bowie E, Goetz S. TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons. elife. 2020;9: pubmed publisher
  2. Wang G, Huang T, Hu Y, Wang K, Shi H, Yin L, et al. Corpus cavernosum smooth muscle cell dysfunction and phenotype transformation are related to erectile dysfunction in prostatitis rats with chronic prostatitis/chronic pelvic pain syndrome. J Inflamm (Lond). 2020;17:2 pubmed publisher
  3. Cohen T, Takahashi V, Bonnell J, Tovchigrechko A, Chaerkady R, Yu W, et al. Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice. J Clin Invest. 2019;129:2133-2144 pubmed publisher
  4. Atakpa P, Thillaiappan N, Mataragka S, Prole D, Taylor C. IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes. Cell Rep. 2018;25:3180-3193.e7 pubmed publisher
  5. Kim J, Ko A, Hyun H, Min S, Kim J. PDI regulates seizure activity via NMDA receptor redox in rats. Sci Rep. 2017;7:42491 pubmed publisher
  6. Sugiura A, Mattie S, Prudent J, McBride H. Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes. Nature. 2017;542:251-254 pubmed publisher
  7. Dong J, Aulestia F, Assad Kahn S, Zeniou M, Dubois L, El Habr E, et al. Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling. Biochim Biophys Acta Mol Cell Res. 2017;1864:1018-1027 pubmed publisher
  8. Fouka P, Alexopoulos H, Chatzi I, Dedos S, Samiotaki M, Panayotou G, et al. Antibodies to inositol 1,4,5-triphosphate receptor 1 in patients with cerebellar disease. Neurol Neuroimmunol Neuroinflamm. 2017;4:e306 pubmed
  9. Liu X, Song S, Wang Q, Yuan T, He J. A mutation in ?-amyloid precursor protein renders SH?SY5Y cells vulnerable to isoflurane toxicity: The role of inositol 1,4,5?trisphosphate receptors. Mol Med Rep. 2016;14:5435-5442 pubmed publisher
  10. Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, et al. Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS. EMBO Mol Med. 2016;8:1421-1437 pubmed publisher
  11. Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 2016;8:1019-38 pubmed publisher
  12. Wang Y, Li J, Ji G, Zhai K, Wang H, Liu X. The Involvement of Ca(2+) Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis. Chin Med J (Engl). 2016;129:1185-92 pubmed publisher
  13. Martínez Pizarro A, Desviat L, Ugarte M, Perez B, Richard E. Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects. PLoS ONE. 2016;11:e0150357 pubmed publisher
  14. White J, Lin T, Brown A, Arancillo M, Lackey E, Stay T, et al. An optimized surgical approach for obtaining stable extracellular single-unit recordings from the cerebellum of head-fixed behaving mice. J Neurosci Methods. 2016;262:21-31 pubmed publisher
  15. Zuccolo E, Bottino C, Diofano F, Poletto V, Codazzi A, Mannarino S, et al. Constitutive Store-Operated Ca(2+) Entry Leads to Enhanced Nitric Oxide Production and Proliferation in Infantile Hemangioma-Derived Endothelial Colony-Forming Cells. Stem Cells Dev. 2016;25:301-19 pubmed publisher
  16. Xu S, Nam S, Kim J, Das R, Choi S, Nguyen T, et al. Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stress. Cell Death Dis. 2015;6:e1976 pubmed publisher
  17. Feng X, Krogh K, Wu C, Lin Y, Tsai H, Thayer S, et al. Receptor-interacting protein 140 attenuates endoplasmic reticulum stress in neurons and protects against cell death. Nat Commun. 2014;5:4487 pubmed publisher
  18. Guo Y, Han S, Cao J, Liu Q, Zhang T. Screening of allergic components mediated by H(1)R in homoharringtonine injection through H(1)R/CMC-HPLC/MS. Biomed Chromatogr. 2014;28:1607-14 pubmed publisher