This is a Validated Antibody Database (VAD) review about human ITK, based on 4 published articles (read how Labome selects the articles), using ITK antibody in all methods. It is aimed to help Labome visitors find the most suited ITK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ITK synonym: EMT; LPFS1; LYK; PSCTK2

Abcam
domestic rabbit monoclonal (Y401)
  • western blot; human; loading ...; fig 2b
Abcam ITK antibody (Abcam, ab32039) was used in western blot on human samples (fig 2b). Cancer Cell Int (2019) ncbi
Cell Signaling Technology
mouse monoclonal (2F12)
  • western blot; human; 1:1000; loading ...; fig 5m, s3c, s3d
Cell Signaling Technology ITK antibody (CST, 2380) was used in western blot on human samples at 1:1000 (fig 5m, s3c, s3d). Blood Cancer J (2022) ncbi
mouse monoclonal (2F12)
  • immunocytochemistry; human; fig s12
In order to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells, Cell Signaling Technology ITK antibody (Cell signaling, 2380BF) was used in immunocytochemistry on human samples (fig s12). Mol Biol Cell (2016) ncbi
mouse monoclonal (2F12)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology ITK antibody (Cell Signaling Technology, 2F12) was used in western blot on mouse samples (fig 5a). Eur J Immunol (2014) ncbi
Articles Reviewed
  1. Geng X, Wang C, Gao X, Chowdhury P, Weiss J, Villegas J, et al. GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms. Blood Cancer J. 2022;12:149 pubmed publisher
  2. Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed publisher
  3. Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  4. Shiheido H, Aoyama T, Takahashi H, Hanaoka K, Abe T, Nishida E, et al. Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLC?1 following T-cell stimulation. Eur J Immunol. 2014;44:1770-80 pubmed publisher