This is a Validated Antibody Database (VAD) review about human IRS-2, based on 12 published articles (read how Labome selects the articles), using IRS-2 antibody in all methods. It is aimed to help Labome visitors find the most suited IRS-2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IRS-2 synonym: IRS-2

Abcam
domestic rabbit monoclonal (EPR904(2))
  • immunoprecipitation; mouse; 1:100; loading ...; fig s9d
Abcam IRS-2 antibody (Abcam, ab13410) was used in immunoprecipitation on mouse samples at 1:100 (fig s9d). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR904(2))
  • immunohistochemistry; mouse
Abcam IRS-2 antibody (Abcam, ab134101) was used in immunohistochemistry on mouse samples . Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (EPR904(2))
  • western blot; human; 1:2000; loading ...; fig s5c
Abcam IRS-2 antibody (Abcam, ab134101) was used in western blot on human samples at 1:2000 (fig s5c). Genome Biol (2020) ncbi
domestic rabbit monoclonal (EPR904(2))
  • immunohistochemistry - paraffin section; human; loading ...; fig 1d
Abcam IRS-2 antibody (Abcam, EPR904(2)) was used in immunohistochemistry - paraffin section on human samples (fig 1d). Mol Ther Oncolytics (2020) ncbi
domestic rabbit monoclonal (EPR904(2))
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1a
  • western blot; mouse; 1:1000; loading ...; fig 1e
In order to assess the causal relationship between chronic cold exposure and insulin resistance and the mechanisms of how DNA methylation and histone deacetylation regulate cold-reduced insulin resistance, Abcam IRS-2 antibody (Abcam, ABl34101) was used in immunohistochemistry on mouse samples at 1:200 (fig 1a) and in western blot on mouse samples at 1:1000 (fig 1e). Cryobiology (2017) ncbi
domestic rabbit monoclonal (EPR904(2))
  • western blot; mouse; fig 10e
Abcam IRS-2 antibody (Abcam, ab134101) was used in western blot on mouse samples (fig 10e). Front Endocrinol (Lausanne) (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology IRS-2 antibody (Cell Signaling, 3089S) was used in western blot on human samples (fig 4a). Mol Ther Oncolytics (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:25; loading ...; fig 4g
Cell Signaling Technology IRS-2 antibody (Cell Signaling, 4502) was used in western blot on rat samples at 1:25 (fig 4g). Am J Physiol Regul Integr Comp Physiol (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology IRS-2 antibody (Cell Signaling Technology, 4502) was used in western blot on mouse samples at 1:1000 (fig 1a). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology IRS-2 antibody (Cell Signaling Technology, 4502) was used in western blot on human samples (fig 4a). Eur J Obstet Gynecol Reprod Biol (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology IRS-2 antibody (Cell Signaling, 4502) was used in western blot on mouse samples at 1:1000 (fig 6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 6
Cell Signaling Technology IRS-2 antibody (Cell signaling, 3089) was used in western blot on rat samples (fig 6). Mol Metab (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology IRS-2 antibody (Cell signaling, 4502) was used in western blot on mouse samples (fig 4). Nat Immunol (2016) ncbi
Articles Reviewed
  1. Bruce J, Sánchez Alvarez R, Sans M, Sugden S, Qi N, James A, et al. Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps. Nat Commun. 2021;12:4386 pubmed publisher
  2. Meng L, Coleman V, Zhao Y, Ost M, Voigt A, Bunschoten A, et al. Pseudo-Starvation Driven Energy Expenditure Negatively Affects Ovarian Follicle Development. Int J Mol Sci. 2021;22: pubmed publisher
  3. Eyler C, Matsunaga H, Hovestadt V, Vantine S, van Galen P, Bernstein B. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol. 2020;21:174 pubmed publisher
  4. Lee M, Jung K, Song J, Sung M, Ahn S, Lee B, et al. IRS2 Amplification as a Predictive Biomarker in Response to Ceritinib in Small Cell Lung Cancer. Mol Ther Oncolytics. 2020;16:188-196 pubmed publisher
  5. Presby D, Checkley L, Jackman M, Higgins J, Jones K, Giles E, et al. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019;317:R684-R695 pubmed publisher
  6. Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed publisher
  7. He T, Liu Y, Zhao S, Liu H, Wang Z, Shi Y. Comprehensive assessment the expression of core elements related to IGFIR/PI3K pathway in granulosa cells of women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2019;233:134-140 pubmed publisher
  8. Wang X, Wang L, Sun Y, Li R, Deng J, Deng J. DNA methylation and histone deacetylation regulating insulin sensitivity due to chronic cold exposure. Cryobiology. 2017;74:36-42 pubmed publisher
  9. Wang K, Cao P, Wang H, Tang Z, Wang N, Wang J, et al. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep. 2016;6:26229 pubmed publisher
  10. de Castro Barbosa T, Ingerslev L, Alm P, Versteyhe S, Massart J, Rasmussen M, et al. High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring. Mol Metab. 2016;5:184-197 pubmed publisher
  11. Martin B, Chadwick W, Janssens J, Premont R, Schmalzigaug R, Becker K, et al. GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. Front Endocrinol (Lausanne). 2015;6:191 pubmed publisher
  12. Hukelmann J, Anderson K, Sinclair L, Grzes K, Murillo A, Hawkins P, et al. The cytotoxic T cell proteome and its shaping by the kinase mTOR. Nat Immunol. 2016;17:104-12 pubmed publisher