This is a Validated Antibody Database (VAD) review about human IRF7, based on 13 published articles (read how Labome selects the articles), using IRF7 antibody in all methods. It is aimed to help Labome visitors find the most suited IRF7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IRF7 synonym: IMD39; IRF-7H; IRF7A; IRF7B; IRF7C; IRF7H; interferon regulatory factor 7; IRF-7; interferon regulatory factor 7G isoform; interferon regulatory factor-7H

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; human; fig 3a
Cell Signaling Technology IRF7 antibody (Cell Signaling, 4920) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-8)
  • chromatin immunoprecipitation; human; loading ...; fig 8b
In order to show that NFATC3 promotes IRF7-mediated IFN production, Santa Cruz Biotechnology IRF7 antibody (Santa Cruz, sc-74472) was used in chromatin immunoprecipitation on human samples (fig 8b). J Exp Med (2016) ncbi
mouse monoclonal (F-1)
  • EMSA; mouse; loading ...; fig 4a
In order to elucidate how interferon regulatory factors 3 and 7 contribute to immunity to bacterial infections, Santa Cruz Biotechnology IRF7 antibody (Santa Cruz, sc-74471) was used in EMSA on mouse samples (fig 4a). Sci Transl Med (2016) ncbi
BioLegend
mouse monoclonal (12G9A36)
  • flow cytometry; human; loading ...; fig 2d
BioLegend IRF7 antibody (BioLegend, 656008) was used in flow cytometry on human samples (fig 2d). J Clin Invest (2017) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig 8c
Proteintech Group IRF7 antibody (Proteintech, 22392-1-AP) was used in western blot on human samples (fig 8c). J Immunol (2017) ncbi
LifeSpan Biosciences
mouse monoclonal (3D9)
  • immunohistochemistry; human
LifeSpan Biosciences IRF7 antibody (Lifespan Biosciences, LS-B2945) was used in immunohistochemistry on human samples . EMBO J (2011) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; human; fig 3a
Cell Signaling Technology IRF7 antibody (Cell Signaling, 4920) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology IRF7 antibody (Cell Signaling Technology, 4920) was used in western blot on human samples (fig 3e). J Clin Invest (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s4h
Cell Signaling Technology IRF7 antibody (Cell Signaling Technology, 5184) was used in western blot on human samples (fig s4h). Nat Med (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to examine the response and resistance to endocrine therapy in mice, Cell Signaling Technology IRF7 antibody (Cell Signaling Technology, 4920) was used in western blot on mouse samples at 1:1000. Carcinogenesis (2015) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology IRF7 antibody (CST, 5184) was used in western blot on human samples (fig 2a). J Transl Med (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology IRF7 antibody (Cell Signaling Technology, 4920) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500
Cell Signaling Technology IRF7 antibody (Cell Signaling, 4920S) was used in western blot on mouse samples at 1:500. Neurobiol Aging (2014) ncbi
BD Biosciences
mouse monoclonal (K40-321)
  • flow cytometry; human; 1:50
BD Biosciences IRF7 antibody (Becton Dickenson, K40-321) was used in flow cytometry on human samples at 1:50. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, et al. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome. MBio. 2019;10: pubmed publisher
  2. Bi E, Li R, Bover L, Li H, Su P, Ma X, et al. E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. J Clin Invest. 2018;128:4821-4831 pubmed publisher
  3. Mathew N, Baumgartner F, Braun L, O Sullivan D, Thomas S, Waterhouse M, et al. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 2018;24:282-291 pubmed publisher
  4. Veenhuis R, Freeman Z, Korleski J, Cohen L, Massaccesi G, Tomasi A, et al. HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells. J Clin Invest. 2017;127:4352-4364 pubmed publisher
  5. Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, et al. Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex. J Immunol. 2017;198:3690-3704 pubmed publisher
  6. Bao M, Wang Y, Liu Y, Shi P, Lu H, Sha W, et al. NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells. J Exp Med. 2016;213:2383-2398 pubmed
  7. Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, et al. IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections. Sci Transl Med. 2016;8:336ra59 pubmed publisher
  8. Dabydeen S, Kang K, Díaz Cruz E, Alamri A, Axelrod M, Bouker K, et al. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 2015;36:122-32 pubmed publisher
  9. Su Y, Cheng T, Chen C, Chang W, Tsai N, Kung C, et al. Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic Lupus erythematosus. J Transl Med. 2014;12:303 pubmed publisher
  10. Pritchard A, White O, Burel J, Carroll M, Phipps S, Upham J. Asthma is associated with multiple alterations in anti-viral innate signalling pathways. PLoS ONE. 2014;9:e106501 pubmed publisher
  11. Zahoor M, Xue G, Sato H, Murakami T, Takeshima S, Aida Y. HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages. PLoS ONE. 2014;9:e106418 pubmed publisher
  12. Taylor J, Minter M, Newman A, Zhang M, Adlard P, Crack P. Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol Aging. 2014;35:1012-23 pubmed publisher
  13. Restivo G, Nguyen B, Dziunycz P, Ristorcelli E, Ryan R, Özuysal Ö, et al. IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011;30:4571-85 pubmed publisher