This is a Validated Antibody Database (VAD) review about human IRF6, based on 4 published articles (read how Labome selects the articles), using IRF6 antibody in all methods. It is aimed to help Labome visitors find the most suited IRF6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IRF6 synonym: LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1; interferon regulatory factor 6

BioLegend
mouse monoclonal (14B2C16)
  • immunocytochemistry; human; loading ...; fig 7b
BioLegend IRF6 antibody (BioLegend, 14B2C16) was used in immunocytochemistry on human samples (fig 7b). Front Physiol (2018) ncbi
LifeSpan Biosciences
goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...
In order to characterize conditional knockout mice in which Irf6 is ablated only in the late embryonic oral epithelium, LifeSpan Biosciences IRF6 antibody (Lifespan Biosciences, LS-B3231) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. J Dent Res (2017) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2m
Sigma-Aldrich IRF6 antibody (Sigma-Aldrich, SAB2102995) was used in immunohistochemistry on mouse samples (fig 2m). J Dent Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100
In order to demonstrate that enhanced BMP signaling through constitutively active ACVR1 in palatal epithelium causes submucous cleft palate in mice, Sigma-Aldrich IRF6 antibody (Sigma-Aldrich, SAB2102995) was used in immunohistochemistry - frozen section on mouse samples at 1:100. Dev Biol (2016) ncbi
Articles Reviewed
  1. Degen M, Wiederkehr A, La Scala G, Carmann C, Schnyder I, Katsaros C. Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro. Front Physiol. 2018;9:1703 pubmed publisher
  2. Kousa Y, Roushangar R, Patel N, Walter A, Marangoni P, Krumlauf R, et al. IRF6 and SPRY4 Signaling Interact in Periderm Development. J Dent Res. 2017;96:1306-1313 pubmed publisher
  3. Tamasas B, Cox T. Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model. J Dent Res. 2017;96:315-322 pubmed publisher
  4. Noda K, Mishina Y, Komatsu Y. Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice. Dev Biol. 2016;415:306-313 pubmed publisher