This is a Validated Antibody Database (VAD) review about human IRAK2, based on 6 published articles (read how Labome selects the articles), using IRAK2 antibody in all methods. It is aimed to help Labome visitors find the most suited IRAK2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IRAK2 synonym: IRAK-2

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
Abcam IRAK2 antibody (Abcam, ab62419) was used in western blot on mouse samples (fig 3a). Nat Immunol (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 8
  • western blot; human; fig 8
In order to identify species-specific preferences in signaling protein use by comprehensive RNAi-based screening of human and mouse TLR pathways, Abcam IRAK2 antibody (Abcam, ab62419) was used in western blot on mouse samples (fig 8) and in western blot on human samples (fig 8). Sci Signal (2016) ncbi
Abnova
mouse monoclonal (1A6)
  • western blot; human
Abnova IRAK2 antibody (Abnova, H00003656-M04) was used in western blot on human samples . Mol Biol Cell (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology IRAK2 antibody (Cell Signaling Technology, 4367) was used in western blot on mouse samples at 1:1000 (fig 3a). J Clin Invest (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s6
Cell Signaling Technology IRAK2 antibody (Cell Signaling Tech, 4367) was used in western blot on human samples at 1:1000 (fig s6). Nat Commun (2016) ncbi
ProSci
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2b, s2g
ProSci IRAK2 antibody (Prosci, 3595) was used in western blot on mouse samples (fig 2b, s2g). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 8
  • western blot; human; fig 8
In order to identify species-specific preferences in signaling protein use by comprehensive RNAi-based screening of human and mouse TLR pathways, ProSci IRAK2 antibody (ProSci, 3595) was used in western blot on mouse samples (fig 8) and in western blot on human samples (fig 8). Sci Signal (2016) ncbi
Articles Reviewed
  1. Zhou H, Wang H, Yu M, Schugar R, Qian W, Tang F, et al. IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nat Immunol. 2020;21:1219-1231 pubmed publisher
  2. Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed publisher
  3. Zhang C, Jiang M, Zhou H, Liu W, Wang C, Kang Z, et al. TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation. J Clin Invest. 2018;128:5399-5412 pubmed publisher
  4. Rasmussen M, Lyskjær I, Jersie Christensen R, Tarpgaard L, Primdal Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed publisher
  5. Sun J, Li N, Oh K, Dutta B, Vayttaden S, Lin B, et al. Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use. Sci Signal. 2016;9:ra3 pubmed publisher
  6. Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed publisher