This is a Validated Antibody Database (VAD) review about human IL21R, based on 9 published articles (read how Labome selects the articles), using IL21R antibody in all methods. It is aimed to help Labome visitors find the most suited IL21R antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IL21R synonym: CD360; IMD56; NILR; interleukin-21 receptor; IL-21 receptor; novel interleukin receptor

BioLegend
mouse monoclonal (2G1-K12)
  • flow cytometry; human; 1:50; loading ...; fig 7m
BioLegend IL21R antibody (Biolegend, 347807) was used in flow cytometry on human samples at 1:50 (fig 7m). elife (2019) ncbi
mouse monoclonal (2G1-K12)
  • flow cytometry; human; 1:100; loading ...; fig 3b
BioLegend IL21R antibody (Biolegend, 2G1-K12) was used in flow cytometry on human samples at 1:100 (fig 3b). elife (2019) ncbi
mouse monoclonal (17A12)
  • flow cytometry; human; loading ...; fig s2b
BioLegend IL21R antibody (Biolegend, 17A12) was used in flow cytometry on human samples (fig s2b). Front Immunol (2018) ncbi
mouse monoclonal (17A12)
  • flow cytometry; human; fig 4a
In order to investigate the role of dopamine in B cell maturation in germinal centres, BioLegend IL21R antibody (BioLegend, 17A12) was used in flow cytometry on human samples (fig 4a). Nature (2017) ncbi
mouse monoclonal (2G1-K12)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BioLegend IL21R antibody (BioLegen d, 347806) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
R&D Systems
R&D Systems IL21R antibody (R&D, 991-R2-100) was used . Nat Immunol (2014) ncbi
BD Biosciences
mouse monoclonal (17A12)
  • flow cytometry; human; loading ...; fig 3c
BD Biosciences IL21R antibody (BD Bioscience, 17A12) was used in flow cytometry on human samples (fig 3c). Haematologica (2017) ncbi
mouse monoclonal (17A12)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences IL21R antibody (BD, 560264) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (17A12)
  • flow cytometry; human; tbl s1
BD Biosciences IL21R antibody (BD Biosciences, 17A12) was used in flow cytometry on human samples (tbl s1). PLoS ONE (2015) ncbi
mouse monoclonal (17A12)
  • flow cytometry; human
BD Biosciences IL21R antibody (BD, 17A12) was used in flow cytometry on human samples . Nat Commun (2014) ncbi
Articles Reviewed
  1. Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
  2. Spolski R, West E, Li P, Veenbergen S, Yung S, Kazemian M, et al. IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus. elife. 2019;8: pubmed publisher
  3. Dam E, Maier A, Hocking A, Carlin J, Buckner J. Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol. 2018;9:1978 pubmed publisher
  4. Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
  5. Bolzoni M, Ronchetti D, Storti P, Donofrio G, Marchica V, Costa F, et al. IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts. Haematologica. 2017;102:773-784 pubmed publisher
  6. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  7. Weinberg A, Muresan P, Richardson K, Fenton T, Domínguez T, Bloom A, et al. Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine. PLoS ONE. 2015;10:e0122431 pubmed publisher
  8. Willmann K, Klaver S, DoÄŸu F, Santos Valente E, Garncarz W, Bilic I, et al. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun. 2014;5:5360 pubmed publisher
  9. Vegran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, et al. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat Immunol. 2014;15:758-66 pubmed publisher