This is a Validated Antibody Database (VAD) review about human IL1A, based on 25 published articles (read how Labome selects the articles), using IL1A antibody in all methods. It is aimed to help Labome visitors find the most suited IL1A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IL1A synonym: IL-1 alpha; IL-1A; IL1; IL1-ALPHA; IL1F1

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4d
Abcam IL1A antibody (Abcam, ab7632) was used in western blot on mouse samples (fig 4d). Aging Cell (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 4f
Abcam IL1A antibody (Abcam, ab9614) was used in immunohistochemistry - paraffin section on human samples (fig 4f). Aging Cell (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4a
Abcam IL1A antibody (Abcam, ab7632) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4a). Oncotarget (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1d
In order to explore the contribution of epithelial cells to systemic sclerosis pathogenesis, Abcam IL1A antibody (Abcam, ab9614) was used in western blot on human samples (fig 1d). J Exp Med (2017) ncbi
domestic rabbit polyclonal
  • blocking or activating experiments; rat; loading ...; fig s3d
In order to identify an astrocyte subtype induced by activated microglia, Abcam IL1A antibody (Abcam, ab9614) was used in blocking or activating experiments on rat samples (fig s3d). Nature (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; fig s1e
  • western blot; mouse; 1:1000; fig s1h
Abcam IL1A antibody (Abcam, 9614) was used in immunohistochemistry on mouse samples at 1:500 (fig s1e) and in western blot on mouse samples at 1:1000 (fig s1h). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; fig 3c
  • western blot; human; fig 1d
Abcam IL1A antibody (Abcam, ab9614) was used in immunohistochemistry on human samples (fig 3c) and in western blot on human samples (fig 1d). Genes Dev (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000
Abcam IL1A antibody (Abcam, ab7632) was used in western blot on rat samples at 1:1000. Mol Neurobiol (2016) ncbi
R&D Systems
mouse monoclonal (4414)
  • immunocytochemistry; human; loading ...; fig s5f
R&D Systems IL1A antibody (R&D, MAB200) was used in immunocytochemistry on human samples (fig s5f). Cell Death Differ (2022) ncbi
mouse monoclonal (4414)
  • western blot; human; loading ...
R&D Systems IL1A antibody (R&D Systems, MAB200) was used in western blot on human samples . Cell Rep (2021) ncbi
Invitrogen
domestic rabbit polyclonal
In order to investigate the effects of cell death and its products on intestinal epithelial cells with a focus on inflammatory bowel disease, Invitrogen IL1A antibody (Thermo Scientific, PA5-25921) was used . Am J Pathol (2015) ncbi
mouse monoclonal (624B3F2)
  • flow cytometry; human
In order to study the influence of cyclodextrin polysulphate on the extracellular matrix metabolism of human articular cartilage chondrocytes, Invitrogen IL1A antibody (Biosource, 624B3F2) was used in flow cytometry on human samples . Osteoarthritis Cartilage (2005) ncbi
mouse monoclonal (624B3F2)
In order to discuss the use of flow cytometry to study the phenotype and function of human articular cartilage cells, Invitrogen IL1A antibody (Biosource, 624B3F2) was used . Methods Mol Med (2004) ncbi
mouse monoclonal (624B3F2)
  • flow cytometry; human
In order to examine the effects of hydrocortisone on synthesis and turnover of cell associated matrix by human chondrocytes, Invitrogen IL1A antibody (Biosource, 624B3F2) was used in flow cytometry on human samples . Ann Rheum Dis (2004) ncbi
mouse monoclonal (624B3F2)
  • flow cytometry; human
In order to study IGF-1/IGFR1 and IL-1/IL-1R pathways in osteoarthritic articular cartilage, Invitrogen IL1A antibody (Biosource, 624B3F2) was used in flow cytometry on human samples . Osteoarthritis Cartilage (2003) ncbi
mouse monoclonal (624B3F2)
  • flow cytometry; human
In order to examine the effect of insulin-like growth factor 1 on human chondrocytes, Invitrogen IL1A antibody (BioSource, 624B3F2) was used in flow cytometry on human samples . Arthritis Rheum (2003) ncbi
BioLegend
mouse monoclonal (364-3B3-14)
  • flow cytometry; African green monkey; loading ...; fig 1i
In order to discuss the use of flow cytometry to examine common marmosets, BioLegend IL1A antibody (BioLegend, 364-3B3-14) was used in flow cytometry on African green monkey samples (fig 1i). J Med Primatol (2016) ncbi
mouse monoclonal (364-3B3-14)
  • dot blot; human; tbl s1
In order to use polydimethylsiloxane microchambers to co-detect 42 immune effector proteins secreted from a single LPS-stimulation macrophage, BioLegend IL1A antibody (Biolegend, 500104) was used in dot blot on human samples (tbl s1). Proc Natl Acad Sci U S A (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3564/3B3-14)
  • western blot; human; fig s1
Santa Cruz Biotechnology IL1A antibody (santa Cruz, sc-73494) was used in western blot on human samples (fig s1). Sci Rep (2015) ncbi
hamsters monoclonal (ALF-161)
  • western blot; mouse; fig 3
Santa Cruz Biotechnology IL1A antibody (santa Cruz, ALF-161) was used in western blot on mouse samples (fig 3). Sci Rep (2015) ncbi
BD Biosciences
mouse monoclonal (364-3B3-14)
  • flow cytometry; human; loading ...; fig 2b
In order to study the effect off HIV 1 vaccination in HIV carriers, BD Biosciences IL1A antibody (BD Biosciences, 364-3B3-14) was used in flow cytometry on human samples (fig 2b). Front Immunol (2017) ncbi
mouse monoclonal (364-3B3-14)
  • other; human; loading ...; fig s1
In order to investigate the mechanisms of toxicity by the negative allosteric modulators of metabotropic glutamate receptor 5, BD Biosciences IL1A antibody (BD/Pharm, 551223) was used in other on human samples (fig s1). Cell Chem Biol (2017) ncbi
mouse monoclonal (AS10)
  • flow cytometry; human; loading ...
In order to report that IgA-producing plasma cells are a major source of inducible NO synthase in Helicobacter pylori-infected patients, BD Biosciences IL1A antibody (BD, AS10) was used in flow cytometry on human samples . J Immunol (2016) ncbi
mouse monoclonal (364-3B3-14)
  • flow cytometry; human; loading ...; tbl 2
In order to assess the protective immunological events induced by vaccination with Leishmune in dogs, BD Biosciences IL1A antibody (BD Biosciences, 554561) was used in flow cytometry on human samples (tbl 2). Vet Parasitol (2016) ncbi
mouse monoclonal (364-3B3-14)
  • flow cytometry; dogs; fig 2
  • flow cytometry; human; fig 2
BD Biosciences IL1A antibody (BD, 554561) was used in flow cytometry on dogs samples (fig 2) and in flow cytometry on human samples (fig 2). Acta Vet Scand (2015) ncbi
mouse monoclonal (AS10)
  • flow cytometry; human; fig 6
BD Biosciences IL1A antibody (BD, 340515) was used in flow cytometry on human samples (fig 6). J Exp Med (2015) ncbi
Articles Reviewed
  1. Fernández Duran I, Quintanilla A, Tarrats N, Birch J, Hari P, Millar F, et al. Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence. Cell Death Differ. 2022;29:1267-1282 pubmed publisher
  2. Lee H, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, et al. Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury. Aging Cell. 2021;20:e13407 pubmed publisher
  3. Goncalves S, Yin K, Ito Y, Chan A, Olan I, Gough S, et al. COX2 regulates senescence secretome composition and senescence surveillance through PGE2. Cell Rep. 2021;34:108860 pubmed publisher
  4. Moreno Valladares M, Moreno Cugnon L, Silva T, Garcés J, Sáenz Antoñanzas A, Álvarez Satta M, et al. CD8+ T cells are increased in the subventricular zone with physiological and pathological aging. Aging Cell. 2020;:e13198 pubmed publisher
  5. Dosh R, Jordan Mahy N, Sammon C, Le Maitre C. Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model. Oncotarget. 2019;10:3559-3575 pubmed publisher
  6. Vitallé J, Zenarruzabeitia O, Terrén I, Plana M, Guardo A, Leal L, et al. Monocytes Phenotype and Cytokine Production in Human Immunodeficiency Virus-1 Infected Patients Receiving a Modified Vaccinia Ankara-Based HIV-1 Vaccine: Relationship to CD300 Molecules Expression. Front Immunol. 2017;8:836 pubmed publisher
  7. Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
  8. Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
  9. Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed publisher
  10. Neumann L, Mueller M, Moos V, Heller F, Meyer T, Loddenkemper C, et al. Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients. J Immunol. 2016;197:1801-8 pubmed publisher
  11. Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
  12. Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed publisher
  13. Moreira M, Costa Pereira C, Alves M, Marteleto B, Ribeiro V, Peruhype Magalhães V, et al. Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes. Vet Parasitol. 2016;220:33-45 pubmed publisher
  14. Capell B, Drake A, Zhu J, Shah P, Dou Z, Dorsey J, et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev. 2016;30:321-36 pubmed publisher
  15. Cohen I, Idan C, Rider P, Peleg R, Vornov E, Elena V, et al. IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity. Sci Rep. 2015;5:14756 pubmed publisher
  16. Moreira M, Dorneles E, Soares R, Magalhães C, Costa Pereira C, Lage A, et al. Cross-reactivity of commercially available anti-human monoclonal antibodies with canine cytokines: establishment of a reliable panel to detect the functional profile of peripheral blood lymphocytes by intracytoplasmic staining. Acta Vet Scand. 2015;57:51 pubmed publisher
  17. Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, et al. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia. J Exp Med. 2015;212:939-51 pubmed publisher
  18. Scarpa M, Kessler S, Sadler T, West G, Homer C, McDonald C, et al. The epithelial danger signal IL-1α is a potent activator of fibroblasts and reactivator of intestinal inflammation. Am J Pathol. 2015;185:1624-37 pubmed publisher
  19. Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed publisher
  20. Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed publisher
  21. Verdonk P, Wang J, Groeneboer S, Broddelez C, Elewaut D, Veys E, et al. Cyclodextrin polysulphates repress IL-1 and promote the accumulation of chondrocyte extracellular matrix. Osteoarthritis Cartilage. 2005;13:887-95 pubmed
  22. Verbruggen G, Wang J, Wang L, Elewaut D, Veys E. Analysis of chondrocyte functional markers and pericellular matrix components by flow cytometry. Methods Mol Med. 2004;100:183-208 pubmed
  23. Wang J, Elewaut D, Hoffman I, Veys E, Verbruggen G. Physiological levels of hydrocortisone maintain an optimal chondrocyte extracellular matrix metabolism. Ann Rheum Dis. 2004;63:61-6 pubmed
  24. Wang J, Verdonk P, Elewaut D, Veys E, Verbruggen G. Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro. Osteoarthritis Cartilage. 2003;11:801-9 pubmed
  25. Wang J, Elewaut D, Veys E, Verbruggen G. Insulin-like growth factor 1-induced interleukin-1 receptor II overrides the activity of interleukin-1 and controls the homeostasis of the extracellular matrix of cartilage. Arthritis Rheum. 2003;48:1281-91 pubmed