This is a Validated Antibody Database (VAD) review about human IL 21, based on 11 published articles (read how Labome selects the articles), using IL 21 antibody in all methods. It is aimed to help Labome visitors find the most suited IL 21 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IL 21 synonym: CVID11; IL-21; Za11; interleukin-21; interleukin-21 isoform

Invitrogen
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human; loading ...
In order to find that oral administration of a selective Rho-associated kinase 2 inhibitor, KD025, reduces psoriasis area in 46% of patients with psoriasis vulgaris, Invitrogen IL 21 antibody (eBioscience, 50-7219) was used in flow cytometry on human samples . J Immunol (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2c
In order to measure interleukin-21 and phosphorylated extracellular signal regulated kinase 1/2 and correlate the findings with clinical and prognostic variables of Kimura disease, Invitrogen IL 21 antibody (Thermo Fisher, PA5-34801) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2c). J Clin Pathol (2017) ncbi
mouse monoclonal (eBio2B2-G20 (2B2-G20))
  • flow cytometry; human; loading ...; fig 1d
In order to explore the role of IL-21-producing T cells in rheumatoid arthritis, Invitrogen IL 21 antibody (eBioscience, eBio2B2-G20) was used in flow cytometry on human samples (fig 1d). J Leukoc Biol (2017) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human; loading ...; fig 2b
Invitrogen IL 21 antibody (eBiosciences, 3A3-N2) was used in flow cytometry on human samples (fig 2b). PLoS ONE (2016) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human; loading ...; fig 5e
In order to demonstrate that TGF-beta induces the differentiation of human CXCL13-producing CD4 positive T cells from naive CD4 positive T cells, Invitrogen IL 21 antibody (eBioscience, 3A3-N2) was used in flow cytometry on human samples (fig 5e). Eur J Immunol (2016) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human; loading ...; fig 1a
In order to investigate the effect of miRNA-155 in IL-21 signaling in white cells and it role in systemic lupues erythematosus., Invitrogen IL 21 antibody (eBioscience, 3A3-N2) was used in flow cytometry on human samples (fig 1a). Arthritis Res Ther (2015) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human
Invitrogen IL 21 antibody (eBioscience, 3A3-N2) was used in flow cytometry on human samples . J Immunol (2014) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; human
In order to use semantic connectivity maps to find biomarkers for multiple sclerosis, Invitrogen IL 21 antibody (eBioscience, 3A3-N2) was used in flow cytometry on human samples . Immun Ageing (2013) ncbi
mouse monoclonal (eBio3A3-N2 (3A3-N2))
  • flow cytometry; mouse
Invitrogen IL 21 antibody (eBioscience, 3A3-N2) was used in flow cytometry on mouse samples . J Exp Med (2010) ncbi
BioLegend
mouse monoclonal (3A3-N2)
  • flow cytometry; African green monkey; loading ...; fig 1f
In order to discuss the use of flow cytometry to examine common marmosets, BioLegend IL 21 antibody (BioLegend, 3A3-N2) was used in flow cytometry on African green monkey samples (fig 1f). J Med Primatol (2016) ncbi
mouse monoclonal (3A3-N2)
  • flow cytometry; Rhesus monkey; loading ...; fig 1b
In order to use lymph node fine-needle aspiration to examine the dynamics of T-follicular helper cells during SIV infection, BioLegend IL 21 antibody (BioLegend, 3A3-N2) was used in flow cytometry on Rhesus monkey samples (fig 1b). J Med Primatol (2015) ncbi
Articles Reviewed
  1. Zanin Zhorov A, Weiss J, Trzeciak A, Chen W, Zhang J, Nyuydzefe M, et al. Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10. J Immunol. 2017;198:3809-3814 pubmed publisher
  2. Chen Q, Li C, Shao B, Gong Z, Liu H, Ling B, et al. Expression of the interleukin-21 and phosphorylated extracellular signal regulated kinase 1/2 in Kimura disease. J Clin Pathol. 2017;70:684-689 pubmed publisher
  3. Lebre M, Vieira P, Tang M, Aarrass S, Helder B, Newsom Davis T, et al. Synovial IL-21/TNF-producing CD4+ T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes. J Leukoc Biol. 2017;101:775-783 pubmed publisher
  4. Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
  5. Li L, Jiang Y, Lao S, Yang B, Yu S, Zhang Y, et al. Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12. PLoS ONE. 2016;11:e0147356 pubmed publisher
  6. Kobayashi S, Watanabe T, Suzuki R, Furu M, Ito H, Ito J, et al. TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells. Eur J Immunol. 2016;46:360-71 pubmed publisher
  7. Klippert A, Stolte Leeb N, Neumann B, Sauermann U, Daskalaki M, Gawanbacht A, et al. Frequencies of lymphoid T-follicular helper cells obtained longitudinally by lymph node fine-needle aspiration correlate significantly with viral load in SIV-infected rhesus monkeys. J Med Primatol. 2015;44:253-62 pubmed publisher
  8. Rasmussen T, Andersen T, Bak R, Yiu G, Sørensen C, Stengaard Pedersen K, et al. Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus. Arthritis Res Ther. 2015;17:154 pubmed publisher
  9. Herati R, Reuter M, Dolfi D, Mansfield K, Aung H, Badwan O, et al. Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults. J Immunol. 2014;193:3528-37 pubmed publisher
  10. Gironi M, Saresella M, Rovaris M, Vaghi M, Nemni R, Clerici M, et al. A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. Immun Ageing. 2013;10:1 pubmed publisher
  11. Batten M, Ramamoorthi N, Kljavin N, Ma C, Cox J, Dengler H, et al. IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells. J Exp Med. 2010;207:2895-906 pubmed publisher