This is a Validated Antibody Database (VAD) review about human IFITM3, based on 8 published articles (read how Labome selects the articles), using IFITM3 antibody in all methods. It is aimed to help Labome visitors find the most suited IFITM3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IFITM3 synonym: 1-8U; DSPA2b; IP15; interferon-induced transmembrane protein 3; dispanin subfamily A member 2b; interferon-inducible protein 1-8U

Knockout validation
Abcam
rabbit monoclonal (EPR5242)
  • western blot knockout validation; human; loading ...; fig s4c, s4d
  • flow cytometry; human; loading ...; fig 1a, s1a, 3a
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot knockout validation; mouse; loading ...; fig 5e
Abcam IFITM3 antibody (Abcam, ab109429) was used in western blot knockout validation on human samples (fig s4c, s4d), in flow cytometry on human samples (fig 1a, s1a, 3a), in immunocytochemistry on human samples (fig 2a) and in western blot knockout validation on mouse samples (fig 5e). Proc Natl Acad Sci U S A (2018) ncbi
Proteintech Group
mouse monoclonal (2E8D12)
  • western blot knockout validation; human; loading ...; fig s4c
  • immunocytochemistry; human; loading ...; fig s3c, 3c
Proteintech Group IFITM3 antibody (Proteintech, 66081-1-Ig) was used in western blot knockout validation on human samples (fig s4c) and in immunocytochemistry on human samples (fig s3c, 3c). Proc Natl Acad Sci U S A (2018) ncbi
GeneTex
rabbit polyclonal
  • western blot knockout validation; human; fig 5a
GeneTex IFITM3 antibody (GeneTex, GTX115407) was used in western blot knockout validation on human samples (fig 5a). Cell (2018) ncbi
Proteintech Group
mouse monoclonal (2E8D12)
  • western blot knockout validation; human; loading ...; fig s4c
  • immunocytochemistry; human; loading ...; fig s3c, 3c
Proteintech Group IFITM3 antibody (Proteintech, 66081-1-Ig) was used in western blot knockout validation on human samples (fig s4c) and in immunocytochemistry on human samples (fig s3c, 3c). Proc Natl Acad Sci U S A (2018) ncbi
rabbit polyclonal
  • flow cytometry; human; loading ...; fig 1b
  • immunocytochemistry; human; loading ...
Proteintech Group IFITM3 antibody (Proteintech, 11714-1-AP) was used in flow cytometry on human samples (fig 1b) and in immunocytochemistry on human samples . EMBO J (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; human; 1:1000; fig 4
  • western blot; human; 1:1000; fig 7
In order to examine the relationship between NEDD4 and IFITM3, Proteintech Group IFITM3 antibody (Proteintech Group, 11714-1-AP) was used in immunoprecipitation on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:1000 (fig 7). PLoS Pathog (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse
Proteintech Group IFITM3 antibody (PROTEINTECH GROUP INC, 11714-1-AP) was used in immunohistochemistry on mouse samples . Med Microbiol Immunol (2015) ncbi
Abcam
rabbit monoclonal (EPR5242)
  • western blot knockout validation; human; loading ...; fig s4c, s4d
  • flow cytometry; human; loading ...; fig 1a, s1a, 3a
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot knockout validation; mouse; loading ...; fig 5e
Abcam IFITM3 antibody (Abcam, ab109429) was used in western blot knockout validation on human samples (fig s4c, s4d), in flow cytometry on human samples (fig 1a, s1a, 3a), in immunocytochemistry on human samples (fig 2a) and in western blot knockout validation on mouse samples (fig 5e). Proc Natl Acad Sci U S A (2018) ncbi
rabbit monoclonal (EPR5242)
  • flow cytometry; human; loading ...; fig ev1a
  • western blot; human; loading ...; fig 1a
Abcam IFITM3 antibody (Abcam, EPR5242/ab109429) was used in flow cytometry on human samples (fig ev1a) and in western blot on human samples (fig 1a). EMBO J (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-41)
  • western blot; human; fig 3a
Santa Cruz Biotechnology IFITM3 antibody (Santa Cruz, sc-100768) was used in western blot on human samples (fig 3a). J Virol (2018) ncbi
Abnova
mouse monoclonal (4C8-1B10)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 5d
  • western blot; mouse; fig 5c
  • immunohistochemistry - paraffin section; human; 1:1000; fig 1a
  • immunocytochemistry; human; fig 6a
  • western blot; human; fig 3b
Abnova IFITM3 antibody (Abnova, H00010410-M01) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 5d), in western blot on mouse samples (fig 5c), in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1a), in immunocytochemistry on human samples (fig 6a) and in western blot on human samples (fig 3b). Clin Cancer Res (2011) ncbi
GeneTex
rabbit polyclonal
  • western blot knockout validation; human; fig 5a
GeneTex IFITM3 antibody (GeneTex, GTX115407) was used in western blot knockout validation on human samples (fig 5a). Cell (2018) ncbi
R&D Systems
goat polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig s4a
  • western blot; human; 1 ug/ml; loading ...; fig 1e
R&D Systems IFITM3 antibody (R&D Systems, AF4834) was used in immunocytochemistry on human samples at 1:100 (fig s4a) and in western blot on human samples at 1 ug/ml (fig 1e). Proc Natl Acad Sci U S A (2017) ncbi
Articles Reviewed
  1. Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  2. Feng J, Wickenhagen A, Turnbull M, Rezelj V, Kreher F, Tilston Lunel N, et al. Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20. J Virol. 2018;92: pubmed publisher
  3. Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
  4. Wu W, Grotefend C, Tsai M, Wang Y, Radic V, Eoh H, et al. ?20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc Natl Acad Sci U S A. 2017;114:7112-7117 pubmed publisher
  5. Monel B, Compton A, Bruel T, Amraoui S, Burlaud Gaillard J, Roy N, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. EMBO J. 2017;36:1653-1668 pubmed publisher
  6. Chesarino N, McMichael T, Yount J. E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3. PLoS Pathog. 2015;11:e1005095 pubmed publisher
  7. Yu M, Qi W, Huang Z, Zhang K, Ye J, Liu R, et al. Expression profile and histological distribution of IFITM1 and IFITM3 during H9N2 avian influenza virus infection in BALB/c mice. Med Microbiol Immunol. 2015;204:505-14 pubmed publisher
  8. Li D, Peng Z, Tang H, Wei P, Kong X, Yan D, et al. KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis. Clin Cancer Res. 2011;17:3558-68 pubmed publisher