This is a Validated Antibody Database (VAD) review about human IDH2, based on 9 published articles (read how Labome selects the articles), using IDH2 antibody in all methods. It is aimed to help Labome visitors find the most suited IDH2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IDH2 synonym: D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH; isocitrate dehydrogenase [NADP], mitochondrial; NADP(+)-specific ICDH; isocitrate dehydrogenase 2 (NADP+), mitochondrial; oxalosuccinate decarboxylase

Abcam
rabbit monoclonal (EPR7577)
  • western blot; human; loading ...; fig 5g
Abcam IDH2 antibody (Abcam, ab131263) was used in western blot on human samples (fig 5g). Cell Stem Cell (2017) ncbi
mouse monoclonal
  • western blot; human; 1:50; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Abcam IDH2 antibody (abcam, ab55271) was used in western blot on human samples at 1:50 (fig st1). Nat Commun (2016) ncbi
mouse monoclonal
  • western blot; human; fig 3
In order to study the support of redox homeostasis during anchorage-independent growth by reductive carboxylation, Abcam IDH2 antibody (Abcam, ab55271) was used in western blot on human samples (fig 3). Nature (2016) ncbi
mouse monoclonal
  • western blot; human; tbl 1
Abcam IDH2 antibody (Abcam, Ab55271) was used in western blot on human samples (tbl 1). elife (2016) ncbi
mouse monoclonal
  • western blot; human; tbl 1
Abcam IDH2 antibody (Abcam, ab55271) was used in western blot on human samples (tbl 1). elife (2016) ncbi
mouse monoclonal
  • western blot; human; 1:1000
Abcam IDH2 antibody (Abcam, ab55271) was used in western blot on human samples at 1:1000. Nat Commun (2015) ncbi
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig s4
Novus Biologicals IDH2 antibody (Novus Biologicals, NBP2-22166) was used in immunocytochemistry on human samples at 1:100 (fig s4). Nature (2014) ncbi
Sigma-Aldrich
mouse monoclonal (5F11)
  • western blot; human; fig 2a
Sigma-Aldrich IDH2 antibody (Sigma, 5F11) was used in western blot on human samples (fig 2a). Sci Rep (2017) ncbi
goat polyclonal
  • western blot; human; 0.3 ug/ml; fig s2d
Sigma-Aldrich IDH2 antibody (Sigma, SAB2501533) was used in western blot on human samples at 0.3 ug/ml (fig s2d). Cell Death Dis (2015) ncbi
Articles Reviewed
  1. Li X, Tan J, Xiao Z, Zhao Y, Han S, Liu D, et al. Transplantation of hUC-MSCs seeded collagen scaffolds reduces scar formation and promotes functional recovery in canines with chronic spinal cord injury. Sci Rep. 2017;7:43559 pubmed publisher
  2. Zhu Z, Li C, Zeng Y, Ding J, Qu Z, Gu J, et al. PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs. Cell Stem Cell. 2017;20:274-289.e7 pubmed publisher
  3. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  4. Jiang L, Shestov A, Swain P, Yang C, Parker S, Wang Q, et al. Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. 2016;532:255-8 pubmed publisher
  5. Richarson A, Scott D, Zagnitko O, Aza Blanc P, Chang C, Russler Germain D. Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation. elife. 2016;5:e10860 pubmed publisher
  6. Fiehn O, Showalter M, Schaner Tooley C. Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. elife. 2016;5: pubmed publisher
  7. Carpentieri A, Cozzoli E, Scimeca M, Bonanno E, Sardanelli A, Gambacurta A. Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor. Cell Death Dis. 2015;6:e1974 pubmed publisher
  8. Lin A, Abbas S, Kim S, Ortega M, Bouamar H, Escobedo Y, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nat Commun. 2015;6:7768 pubmed publisher
  9. Saha S, Parachoniak C, Ghanta K, Fitamant J, Ross K, Najem M, et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature. 2014;513:110-4 pubmed publisher