This is a Validated Antibody Database (VAD) review about human IDH1, based on 32 published articles (read how Labome selects the articles), using IDH1 antibody in all methods. It is aimed to help Labome visitors find the most suited IDH1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
IDH1 synonym: HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD

Dianova
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; tbl 4
Dianova IDH1 antibody (Dianova, DIA-H09) was used in immunohistochemistry - paraffin section on human samples at 1:20 (tbl 4). Front Oncol (2020) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 1
Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Front Neurosci (2020) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a
Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2a). Front Oncol (2019) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 1
Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Neurol Med Chir (Tokyo) (2020) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; loading ...; fig s2h
Dianova IDH1 antibody (Dianova, DIA-H09) was used in immunohistochemistry - paraffin section on human samples (fig s2h). Redox Biol (2020) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry - paraffin section on human samples (fig 2a). Neurosurgery (2018) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; 1:50; loading ...; fig 2o
In order to suggest that CASP9 germline mutations may promote the development of brain tumors, Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry on human samples at 1:50 (fig 2o). Brain Pathol (2018) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; 1:40; loading ...; tbl 1
In order to use mass spectroscopy to classify anaplastic glioma by integration of clinical data, Dianova IDH1 antibody (Diavona, H09) was used in immunohistochemistry - paraffin section on human samples at 1:40 (tbl 1). Biochim Biophys Acta Proteins Proteom (2017) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; loading ...; fig 1a
In order to correlate 1p/19q codeletion, IDH1 mutation and p53 protein overexpression with prognosis in Turkish anaplastic oligodendroglioma patients treated with adjuvant radiotherapy and temozolomide chemotherapy, Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry on human samples (fig 1a). Turk Neurosurg (2017) ncbi
mouse monoclonal (H09)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 1
Dianova IDH1 antibody (Dianova, DIA-H09) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 1). Brain Pathol (2017) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; loading ...; fig 3c
In order to describe the mechanism behind the association between single nucleotide polymorphism rs55705857 and glioma development., Dianova IDH1 antibody (Dianova, DIA-H09) was used in immunohistochemistry on human samples (fig 3c). Sci Rep (2016) ncbi
mouse monoclonal (H09)
  • immunocytochemistry; human; 1:50; fig 2
  • western blot; human; 1:500; fig 9
Dianova IDH1 antibody (Dianova, DIA-H09) was used in immunocytochemistry on human samples at 1:50 (fig 2) and in western blot on human samples at 1:500 (fig 9). PLoS ONE (2016) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; 1:20; loading ...; fig 1c
In order to determine if the isocitrate dehydrogenase R132H mutation is present in pituitary adenomas, Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry on human samples at 1:20 (fig 1c). Pituitary (2016) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; 1:40; tbl 2
In order to characterize eleven cases of primary glial and neuronal tumors of the ovary or peritoneum, Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry on human samples at 1:40 (tbl 2). Am J Surg Pathol (2016) ncbi
mouse monoclonal (H09)
  • western blot; human; 1:500; fig 6
In order to examine the contribution of 5-hydroxymethylation of cellular and viral genes to nasopharyngeal carcinoma, Dianova IDH1 antibody (Dianova, DIA-H09) was used in western blot on human samples at 1:500 (fig 6). Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (H09)
  • immunohistochemistry; human; 1:50; loading ...; tbl 1
Dianova IDH1 antibody (Dianova, H09) was used in immunohistochemistry on human samples at 1:50 (tbl 1). Pathol Int (2016) ncbi
mouse monoclonal (H09)
  • western blot; human
Dianova IDH1 antibody (Dianova, DIA-H09) was used in western blot on human samples . Acta Neuropathol (2014) ncbi
OriGene
mouse monoclonal (OTI24A2)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 1
OriGene IDH1 antibody (Origene Technologies, OTI24A2) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 1). BMC Cancer (2019) ncbi
mouse monoclonal (OTI2H9)
  • western blot; human
OriGene IDH1 antibody (Origene, TA500610) was used in western blot on human samples . Cancer Discov (2014) ncbi
Proteintech Group
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5g
Proteintech Group IDH1 antibody (Proteintech, 12332-1-AP) was used in western blot on human samples (fig 5g). Cell Stem Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 5i
Proteintech Group IDH1 antibody (Proteintech, 12332-1-AP) was used in western blot on mouse samples at 1:2000 (fig 5i). Nat Chem Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; tbl 1
Proteintech Group IDH1 antibody (ProteinTech, 12332-1-AP) was used in western blot on human samples (tbl 1). elife (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR12296)
  • western blot; human; fig s8
In order to characterize D-2-hydroxyglutarate in its oncogenic property of mutant IDH-containing cancer cells but is dispensable for cell growth, Abcam IDH1 antibody (Epitomics, 8057-1) was used in western blot on human samples (fig s8). Oncotarget (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D2H1)
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology IDH1 antibody (CST, 8137) was used in western blot on human samples (fig 2d). Genes Dev (2017) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology IDH1 antibody (CST, 8137) was used in western blot on human samples (fig 5a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology IDH1 antibody (Cell Signaling, 8137) was used in western blot on human samples at 1:1000 (fig 4a). JCI Insight (2016) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology IDH1 antibody (Cell Signaling, 8137) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D2H1)
  • immunocytochemistry; human; 1:400; fig 2
  • western blot; human; 1:1000; fig 9
Cell Signaling Technology IDH1 antibody (Cell Signaling Tech, 8137) was used in immunocytochemistry on human samples at 1:400 (fig 2) and in western blot on human samples at 1:1000 (fig 9). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; 1:1000; fig s11
Cell Signaling Technology IDH1 antibody (cell Signaling Tech, 8137S) was used in western blot on human samples at 1:1000 (fig s11). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; 1:1000
Cell Signaling Technology IDH1 antibody (Cell Signaling Technology, 8137) was used in western blot on human samples at 1:1000. Nat Commun (2015) ncbi
domestic rabbit monoclonal (D2H1)
  • western blot; human; 1:500; fig 2
Cell Signaling Technology IDH1 antibody (Cell Signaling Tech, 8137) was used in western blot on human samples at 1:500 (fig 2). Nat Cell Biol (2015) ncbi
MBL International
  • immunohistochemistry; human; 1:200
In order to determine the mechanisms of bevacizumab resistance, MBL International IDH1 antibody (Medical & Biological Laboratories, D299-3) was used in immunohistochemistry on human samples at 1:200. Brain Tumor Pathol (2016) ncbi
  • immunohistochemistry; human
MBL International IDH1 antibody (MBL, D299?C3) was used in immunohistochemistry on human samples . J Neurosurg (2014) ncbi
Articles Reviewed
  1. Gihr G, Horvath Rizea D, Hekeler E, Ganslandt O, Henkes H, Hoffmann K, et al. Histogram Analysis of Diffusion Weighted Imaging in Low-Grade Gliomas: in vivo Characterization of Tumor Architecture and Corresponding Neuropathology. Front Oncol. 2020;10:206 pubmed publisher
  2. Han Y, Wang W, Yang Y, Sun Y, Xiao G, Tian Q, et al. Amide Proton Transfer Imaging in Predicting Isocitrate Dehydrogenase 1 Mutation Status of Grade II/III Gliomas Based on Support Vector Machine. Front Neurosci. 2020;14:144 pubmed publisher
  3. Lee S, Kambhampati M, Almira Suarez M, Ho C, Panditharatna E, Berger S, et al. Somatic Mosaicism of IDH1 R132H Predisposes to Anaplastic Astrocytoma: A Case of Two Siblings. Front Oncol. 2019;9:1507 pubmed publisher
  4. Suzuki H, Mikuni N, Sugita S, Aoyama T, Yokoyama R, Suzuki Y, et al. Molecular Aberrations Associated with Seizure Control in Diffuse Astrocytic and Oligodendroglial Tumors. Neurol Med Chir (Tokyo). 2020;60:147-155 pubmed publisher
  5. Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  6. Bi C, Liu M, Rong W, Wu F, Zhang Y, Lin S, et al. High Beclin-1 and ARID1A expression corelates with poor survival and high recurrence in intrahepatic cholangiocarcinoma: a histopathological retrospective study. BMC Cancer. 2019;19:213 pubmed publisher
  7. Pratt D, Dominah G, Lobel G, Obungu A, Lynes J, Sanchez V, et al. Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma. Neurosurgery. 2018;: pubmed publisher
  8. Morgan M, Rickels R, Collings C, He X, Cao K, Herz H, et al. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev. 2017;31:2003-2014 pubmed publisher
  9. Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget. 2017;8:28922-28938 pubmed publisher
  10. Zhu Z, Li C, Zeng Y, Ding J, Qu Z, Gu J, et al. PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs. Cell Stem Cell. 2017;20:274-289.e7 pubmed publisher
  11. Ronellenfitsch M, Oh J, Satomi K, Sumi K, Harter P, Steinbach J, et al. CASP9 germline mutation in a family with multiple brain tumors. Brain Pathol. 2018;28:94-102 pubmed publisher
  12. Le Rhun E, Duhamel M, Wisztorski M, Gimeno J, Zairi F, Escande F, et al. Evaluation of non-supervised MALDI mass spectrometry imaging combined with microproteomics for glioma grade III classification. Biochim Biophys Acta Proteins Proteom. 2017;1865:875-890 pubmed publisher
  13. Rahman S, Ji X, Zimmerman L, Li M, Harris B, Hoeksema M, et al. The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer. JCI Insight. 2016;1:e88814 pubmed publisher
  14. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  15. Hacisalihoglu P, Kucukodaci Z, Gundogdu G, Bilgic B. The Correlation Between 1p/19q Codeletion, IDH1 Mutation, p53 Overexpression and Their Prognostic Roles in 41 Turkish Anaplastic Oligodendroglioma Patients. Turk Neurosurg. 2017;27:682-689 pubmed publisher
  16. Bielle F, Ducray F, Mokhtari K, Dehais C, Adle Biassette H, Carpentier C, et al. Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas. Brain Pathol. 2017;27:567-579 pubmed publisher
  17. Oktay Y, Ãœlgen E, Can Ã, Akyerli C, Yüksel Å, Erdemgil Y, et al. IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. Sci Rep. 2016;6:27569 pubmed publisher
  18. Rosiak K, Smolarz M, Stec W, Peciak J, Grzela D, Winiecka Klimek M, et al. IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis. PLoS ONE. 2016;11:e0154726 pubmed publisher
  19. Casar Borota O, Øystese K, Sundstrom M, Melchior L, Popovic V. A high-throughput analysis of the IDH1(R132H) protein expression in pituitary adenomas. Pituitary. 2016;19:407-14 pubmed publisher
  20. Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12:345-52 pubmed publisher
  21. Liang L, Olar A, Niu N, Jiang Y, Cheng W, Bian X, et al. Primary Glial and Neuronal Tumors of the Ovary or Peritoneum: A Clinicopathologic Study of 11 Cases. Am J Surg Pathol. 2016;40:847-56 pubmed publisher
  22. Richarson A, Scott D, Zagnitko O, Aza Blanc P, Chang C, Russler Germain D. Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation. elife. 2016;5:e10860 pubmed publisher
  23. Okamoto S, Nitta M, Maruyama T, Sawada T, Komori T, Okada Y, et al. Bevacizumab changes vascular structure and modulates the expression of angiogenic factors in recurrent malignant gliomas. Brain Tumor Pathol. 2016;33:129-36 pubmed publisher
  24. Wille C, Nawandar D, Henning A, Ma S, Oetting K, Lee D, et al. 5-hydroxymethylation of the EBV genome regulates the latent to lytic switch. Proc Natl Acad Sci U S A. 2015;112:E7257-65 pubmed publisher
  25. Yamaguchi M, Komori T, Nakata Y, Yagishita A, Morino M, Isozaki E. Multinodular and vacuolating neuronal tumor affecting amygdala and hippocampus: A quasi-tumor?. Pathol Int. 2016;66:34-41 pubmed publisher
  26. Aviner R, Shenoy A, Elroy Stein O, Geiger T. Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis. PLoS Genet. 2015;11:e1005554 pubmed publisher
  27. Lin A, Abbas S, Kim S, Ortega M, Bouamar H, Escobedo Y, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nat Commun. 2015;6:7768 pubmed publisher
  28. Ma S, Jiang B, Deng W, Gu Z, Wu F, Li T, et al. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. Oncotarget. 2015;6:8606-20 pubmed
  29. Fong M, Zhou W, Liu L, Alontaga A, Chandra M, Ashby J, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17:183-94 pubmed publisher
  30. Liu Y, Gilbert M, Kyprianou N, Rangnekar V, Horbinski C. The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells. Acta Neuropathol. 2014;128:723-32 pubmed publisher
  31. Ishikawa E, Muragaki Y, Yamamoto T, Maruyama T, Tsuboi K, Ikuta S, et al. Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. J Neurosurg. 2014;121:543-53 pubmed publisher
  32. Elhammali A, Ippolito J, Collins L, Crowley J, Marasa J, Piwnica Worms D. A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor. Cancer Discov. 2014;4:828-39 pubmed publisher