This is a Validated Antibody Database (VAD) review about human ICOSLG, based on 15 published articles (read how Labome selects the articles), using ICOSLG antibody in all methods. It is aimed to help Labome visitors find the most suited ICOSLG antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ICOSLG synonym: B7-H2; B7H2; B7RP-1; B7RP1; B7h; CD275; GL50; ICOS-L; ICOSL; LICOS

BioLegend
mouse monoclonal (2D3)
  • flow cytometry; mouse; 1:100; fig 1k
BioLegend ICOSLG antibody (Biolegend, 309403) was used in flow cytometry on mouse samples at 1:100 (fig 1k). Nat Commun (2021) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; loading ...; fig 2c
BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples (fig 2c). Rheumatology (Oxford) (2020) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; fig 4i
In order to investigate the role of dopamine in B cell maturation in germinal centres, BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples (fig 4i). Nature (2017) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; fig 1b
In order to investigate the role of Vgamma9/Vdelta2 T cells in intestinal IL-22 production, BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples (fig 1b). J Immunol (2017) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; fig 3e
BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples (fig 3e). JCI Insight (2017) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; loading ...; fig 1a
In order to establish the T Cell receptor-inducible costimulator as a promising target for direct T regulatory cell-targeting therapeutic agents for gastric cancer, BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples (fig 1a). Int J Cancer (2017) ncbi
mouse monoclonal (2D3)
  • flow cytometry; human; loading ...
BioLegend ICOSLG antibody (BioLegend, 2D3) was used in flow cytometry on human samples . J Exp Med (2016) ncbi
mouse monoclonal (9F.8A4)
  • flow cytometry; human; loading ...; tbl 1
BioLegend ICOSLG antibody (BioLegend, 9F.8A4) was used in flow cytometry on human samples (tbl 1). J Immunol (2016) ncbi
mouse monoclonal (2D3)
  • other; human; fig 4
  • flow cytometry; human; fig 1a
In order to develop and characterize a mouse anti-human CD275 monoclonal antibody, BioLegend ICOSLG antibody (Biolegend, 2D3) was used in other on human samples (fig 4) and in flow cytometry on human samples (fig 1a). Monoclon Antib Immunodiagn Immunother (2016) ncbi
Invitrogen
mouse monoclonal (MIH12)
  • blocking or activating experiments; human; 10 ug/ml; fig 6
Invitrogen ICOSLG antibody (eBioscience, 16-5889) was used in blocking or activating experiments on human samples at 10 ug/ml (fig 6). Oncoimmunology (2016) ncbi
mouse monoclonal (MIH12)
  • other; human; fig 4
In order to develop and characterize a mouse anti-human CD275 monoclonal antibody, Invitrogen ICOSLG antibody (eBioscience, MIH12) was used in other on human samples (fig 4). Monoclon Antib Immunodiagn Immunother (2016) ncbi
mouse monoclonal (MIH12)
  • flow cytometry; human
Invitrogen ICOSLG antibody (e-Bioscience, MIH12) was used in flow cytometry on human samples . Nat Commun (2014) ncbi
mouse monoclonal (MIH12)
  • flow cytometry; human; 5 ug/ml
Invitrogen ICOSLG antibody (eBioscience, MIH12) was used in flow cytometry on human samples at 5 ug/ml. J Immunol (2006) ncbi
Sino Biological
mouse monoclonal (4H2B1)
  • blocking or activating experiments; human
Sino Biological ICOSLG antibody (Sino Biological, 11559-MM07) was used in blocking or activating experiments on human samples . J Immunol Methods (2015) ncbi
BD Biosciences
mouse monoclonal (2D3/B7-H2)
  • flow cytometry; human; loading ...; fig 1a
BD Biosciences ICOSLG antibody (BD Biosciences, 2D3/B7-H2) was used in flow cytometry on human samples (fig 1a). J Immunol (2016) ncbi
mouse monoclonal (2D3/B7-H2)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences ICOSLG antibody (BD, 552502) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
Articles Reviewed
  1. Arenas E, Martínez Sabadell A, Rius Ruiz I, Román Alonso M, Escorihuela M, Luque A, et al. Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nat Commun. 2021;12:1237 pubmed publisher
  2. Kim J, Jeong J, Jung J, Jeon H, Lee S, Lim J, et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis. Rheumatology (Oxford). 2020;: pubmed publisher
  3. Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
  4. Tyler C, McCarthy N, Lindsay J, Stagg A, Moser B, Eberl M. Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin. J Immunol. 2017;198:3417-3425 pubmed publisher
  5. Martin Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb K, et al. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017;2:e89574 pubmed publisher
  6. Nagase H, Takeoka T, Urakawa S, Morimoto Okazawa A, Kawashima A, Iwahori K, et al. ICOS+ Foxp3+ TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori. Int J Cancer. 2017;140:686-695 pubmed publisher
  7. Tagawa T, Albanese M, Bouvet M, Moosmann A, Mautner J, Heissmeyer V, et al. Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing. J Exp Med. 2016;213:2065-80 pubmed publisher
  8. Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed publisher
  9. Loyon R, Picard E, Mauvais O, Queiroz L, Mougey V, Pallandre J, et al. IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner. J Immunol. 2016;197:85-96 pubmed publisher
  10. Li H, Borrego F, Nagata S, Tolnay M. Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells. J Immunol. 2016;196:4064-74 pubmed publisher
  11. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  12. Hu X, Liu C, An J, Shen Y, Hu Y, Jiang J, et al. Development of a Novel Functional Monoclonal Antibody to Human CD275: Characterization and Biological Activity. Monoclon Antib Immunodiagn Immunother. 2016;35:18-24 pubmed publisher
  13. Vettermann C, Victor H, Sun Y, Plewa C, Gupta S. A signaling-enhanced chimeric receptor to activate the ICOS pathway in T cells. J Immunol Methods. 2015;424:14-9 pubmed publisher
  14. Willmann K, Klaver S, DoÄŸu F, Santos Valente E, Garncarz W, Bilic I, et al. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun. 2014;5:5360 pubmed publisher
  15. Quiroga M, Pasquinelli V, Martinez G, Jurado J, Zorrilla L, Musella R, et al. Inducible costimulator: a modulator of IFN-gamma production in human tuberculosis. J Immunol. 2006;176:5965-74 pubmed