This is a Validated Antibody Database (VAD) review about human ICBP90, based on 18 published articles (read how Labome selects the articles), using ICBP90 antibody in all methods. It is aimed to help Labome visitors find the most suited ICBP90 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ICBP90 synonym: ICBP90; Np95; RNF106; TDRD22; hNP95; hUHRF1; huNp95

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (H-8)
  • western blot knockout validation; human; loading ...; fig s4k
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • chromatin immunoprecipitation; human; loading ...; fig 4g
  • western blot; mouse; fig 1c
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in western blot knockout validation on human samples (fig s4k), in immunohistochemistry - paraffin section on human samples (fig 1a), in chromatin immunoprecipitation on human samples (fig 4g) and in western blot on mouse samples (fig 1c). Theranostics (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-8)
  • immunocytochemistry knockout validation; mouse; 1:100; loading ...; fig s1f
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1e
  • western blot knockout validation; mouse; 1:100; loading ...; fig s1d
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in immunocytochemistry knockout validation on mouse samples at 1:100 (fig s1f), in immunohistochemistry knockout validation on mouse samples at 1:100 (fig s1e) and in western blot knockout validation on mouse samples at 1:100 (fig s1d). Front Cell Dev Biol (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-8)
  • western blot knockout validation; human; loading ...; fig s4k
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • chromatin immunoprecipitation; human; loading ...; fig 4g
  • western blot; mouse; fig 1c
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in western blot knockout validation on human samples (fig s4k), in immunohistochemistry - paraffin section on human samples (fig 1a), in chromatin immunoprecipitation on human samples (fig 4g) and in western blot on mouse samples (fig 1c). Theranostics (2022) ncbi
mouse monoclonal (H-8)
  • western blot; mouse; 1:500; loading ...; fig 2c
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in western blot on mouse samples at 1:500 (fig 2c). iScience (2022) ncbi
mouse monoclonal (H-8)
  • western blot; human; 1:100; loading ...; fig 3m
Santa Cruz Biotechnology ICBP90 antibody (SantaCruz, sc-373750) was used in western blot on human samples at 1:100 (fig 3m). Int J Biol Sci (2021) ncbi
mouse monoclonal (H-8)
  • immunocytochemistry knockout validation; mouse; 1:100; loading ...; fig s1f
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1e
  • western blot knockout validation; mouse; 1:100; loading ...; fig s1d
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in immunocytochemistry knockout validation on mouse samples at 1:100 (fig s1f), in immunohistochemistry knockout validation on mouse samples at 1:100 (fig s1e) and in western blot knockout validation on mouse samples at 1:100 (fig s1d). Front Cell Dev Biol (2020) ncbi
mouse monoclonal (H-8)
  • western blot; human; 1:1000; loading ...; fig s2a
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, Sc-373750) was used in western blot on human samples at 1:1000 (fig s2a). Cell Rep (2019) ncbi
mouse monoclonal (H-8)
  • western blot; mouse; loading ...; fig 1c
Santa Cruz Biotechnology ICBP90 antibody (Santa cruz, Sc373750) was used in western blot on mouse samples (fig 1c). Epigenetics (2017) ncbi
mouse monoclonal (H-8)
  • western blot; human; 1:1000; fig s5
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
mouse monoclonal (H-8)
  • western blot; human; loading ...; fig 6b
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in western blot on human samples (fig 6b). J Biol Chem (2016) ncbi
mouse monoclonal (28)
  • western blot; human; 1:1000; loading ...; fig 1e
Santa Cruz Biotechnology ICBP90 antibody (Santa, sc-136264) was used in western blot on human samples at 1:1000 (fig 1e). J Pathol (2016) ncbi
mouse monoclonal (H-8)
  • immunohistochemistry - paraffin section; human; 1:100
Santa Cruz Biotechnology ICBP90 antibody (Santa Cruz, sc-373750) was used in immunohistochemistry - paraffin section on human samples at 1:100. Nucleic Acids Res (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:500; loading ...; fig 6d
  • western blot; human; 1:1000; loading ...; fig 5b
In order to propose that miR-101- mediated UHRF1 pathways are altered by sunitinib treatment, Invitrogen ICBP90 antibody (Pierce, PA5-29884) was used in immunohistochemistry on human samples at 1:500 (fig 6d) and in western blot on human samples at 1:1000 (fig 5b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:300; loading ...; fig 9c
  • western blot; human; 1:500; loading ...; fig 5b
In order to determine the functional significance of miR-145-3p and bladder cancer oncogenic pathways, Invitrogen ICBP90 antibody (ThermoFisher Scientific, PA5-29884) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig 9c) and in western blot on human samples at 1:500 (fig 5b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human
In order to study the relationship between nuclear LASP-1 and the epigenetic machinery in breast cancer, Invitrogen ICBP90 antibody (Thermo, PA5-27969) was used in western blot on human samples . Oncogene (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR18803-11)
  • western blot; rat; 1:1000; loading ...; fig 1c
Abcam ICBP90 antibody (Abcam, ab213223) was used in western blot on rat samples at 1:1000 (fig 1c). Biosci Rep (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6G8E)
  • chromatin immunoprecipitation; mouse; loading ...; fig 4e
Cell Signaling Technology ICBP90 antibody (Cell Signaling, 12387) was used in chromatin immunoprecipitation on mouse samples (fig 4e). iScience (2022) ncbi
domestic rabbit monoclonal (D6G8E)
  • western blot; human; 1:200; loading ...; fig 6a
Cell Signaling Technology ICBP90 antibody (Cell Signaling, 12387) was used in western blot on human samples at 1:200 (fig 6a). PLoS ONE (2016) ncbi
BD Biosciences
mouse monoclonal (28/ICBP90)
  • western blot; human; loading ...; fig s3f
In order to study long noncoding RNA UPAT, colon tumorigenesis, and UHRF1, BD Biosciences ICBP90 antibody (BD Biosciences, 612264) was used in western blot on human samples (fig s3f). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (28/ICBP90)
  • western blot; human; 1:1000; fig 1
BD Biosciences ICBP90 antibody (BD Science, 612264) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (28/ICBP90)
  • immunocytochemistry; human; 1:200
In order to evaluate diagnostic markers for lung cancer with bronchial brushing specimens, BD Biosciences ICBP90 antibody (BD Bioscience, 612264) was used in immunocytochemistry on human samples at 1:200. Cancer Cytopathol (2014) ncbi
Articles Reviewed
  1. Zhang J, Zhang H, Ding X, Hu J, Li Y, Zhang J, et al. Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression. Theranostics. 2022;12:3776-3793 pubmed publisher
  2. Aibara D, Takahashi S, Yagai T, Kim D, Brocker C, Levi M, et al. Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation. iScience. 2022;25:104196 pubmed publisher
  3. Zheng T, Liu X, Li X, Wang Q, Zhao Y, Li X, et al. Dickkopf-1 promotes Vascular Smooth Muscle Cell proliferation and migration through upregulating UHRF1 during Cyclic Stretch application. Int J Biol Sci. 2021;17:1234-1249 pubmed publisher
  4. Wu Y, Dong J, Feng S, Zhao Q, Duan P, Xiong M, et al. Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition. Front Cell Dev Biol. 2020;8:610773 pubmed publisher
  5. Lopez Martinez D, Kupculak M, Yang D, Yoshikawa Y, Liang C, Wu R, et al. Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage. Cell Rep. 2019;27:2990-3005.e5 pubmed publisher
  6. Chen X, Zhou Y, Liang S, Shi Y, Lin S, Shu M. Overexpression of UHRF1 promoted the proliferation of vascular smooth cells via the regulation of Geminin protein levels. Biosci Rep. 2019;39: pubmed publisher
  7. Liu Y, Zhang B, Meng X, Korn M, Parent J, Lu L, et al. UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures. Epigenetics. 2017;12:551-560 pubmed publisher
  8. Goto Y, Kurozumi A, Nohata N, Kojima S, Matsushita R, Yoshino H, et al. The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma. Oncotarget. 2016;7:59070-59086 pubmed publisher
  9. Liang C, Li Z, Lopez Martinez D, Nicholson W, Venien Bryan C, Cohn M. The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2. Nat Commun. 2016;7:12124 pubmed publisher
  10. Liu Y, Zhang B, Kuang H, Korakavi G, Lu L, Yu X. Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader. J Biol Chem. 2016;291:13679-88 pubmed publisher
  11. Matsushita R, Yoshino H, Enokida H, Goto Y, Miyamoto K, Yonemori M, et al. Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): Inhibition of bladder cancer cell aggressiveness. Oncotarget. 2016;7:28460-87 pubmed publisher
  12. Wotschofsky Z, Gummlich L, Liep J, Stephan C, Kilic E, Jung K, et al. Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p. PLoS ONE. 2016;11:e0148746 pubmed publisher
  13. Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, et al. Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proc Natl Acad Sci U S A. 2016;113:1273-8 pubmed publisher
  14. Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nat Commun. 2016;7:10201 pubmed publisher
  15. Abu Alainin W, Gana T, Liloglou T, Olayanju A, Barrera L, Ferguson R, et al. UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. J Pathol. 2016;238:423-33 pubmed publisher
  16. Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  17. Kim K, Son H, Choi S, Hahm J, Jung H, Baek H, et al. H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation. Nucleic Acids Res. 2015;43:3509-23 pubmed publisher
  18. Liu Y, Jiang Y, Wang B, Hao J, Shang L, Zhang T, et al. A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens. Cancer Cytopathol. 2014;122:833-41 pubmed publisher